Abstract: 2-(4-pyridylaminomethyl)benzimidazole derivatives of the following general formula: ##STR1## and processes for preparing them are described. The potent in vitro and in vivo antipicornavirus activities of the compounds are demonstrated.
Abstract: Provided herein is an antiviral 2-(4-pyridylaminomethyl)-benzimidazole of the formula: ##STR1## wherein R is a radical selected from the groups consisting of hydrogen, short-chain alkyl, short-chain alkoxy, benzoyl, halogenomethyl, halogen, nitro and amino groups; the preparation of these compounds and antiviral composition containing such compounds.