Patents Assigned to Maruzen Pharmaceutical Co., Ltd.
  • Patent number: 10111920
    Abstract: Provided are: a production method for salt-free miso, in which steamed soy beans and koji are pressurized, heated, and fermented; salt-free miso obtained by said production method; and a hepatic function improvement agent and a hypertension improvement agent that contain said salt-free miso as an effective component thereof.
    Type: Grant
    Filed: January 6, 2015
    Date of Patent: October 30, 2018
    Assignees: MARUZEN PHARMACEUTICALS CO., LTD., MASUYAMISO CO., LTD.
    Inventors: Tatsuo Nakahara, Takashi Kawano
  • Publication number: 20170100444
    Abstract: Provided are: a production method for salt-free miso, in which steamed soy beans and koji are pressurized, heated, and fermented; salt-free miso obtained by said production method; and a hepatic function improvement agent and a hypertension improvement agent that contain said salt-free miso as an effective component thereof.
    Type: Application
    Filed: January 6, 2015
    Publication date: April 13, 2017
    Applicants: MARUZEN PHARMACEUTICALS CO., LTD., MASUYAMISO CO., LTD.
    Inventors: Tatsuo NAKAHARA, Takashi KAWANO
  • Patent number: 8828955
    Abstract: The invention aims at finding a highly-safe natural product having glutathione production-enhancing activity, and providing a glutathione production enhancer and a prophylactic/therapeutic agent for diseases caused by glutathione deficiency using that natural product as an active ingredient. The glutathione production enhancer or the prophylactic/therapeutic agent for diseases caused by glutathione deficiency contains, as an active ingredient, a licorice extract composition that contains liquiritin, liquiritigenin, isoliquiritin and isoliquiritigenin but contains substantially no glycyrrhizic acid.
    Type: Grant
    Filed: May 1, 2009
    Date of Patent: September 9, 2014
    Assignee: Maruzen Pharmaceuticals Co., Ltd.
    Inventors: Nobuaki Ohto, Toshiyuki Murakami, Hirokazu Ohno
  • Patent number: 8563054
    Abstract: An anti-inflammatory agent which includes an oil-soluble licorice extract, prepared by subjecting at least one of a leguminous plant of the genus Glycyrrhiza and a water extraction residue of a leguminous plant of the genus Glycyrrhiza to an extraction treatment with an organic solvent and which has at least one effect selected from an inhibitory effect on hyaluronidase activity, an inhibitory effect on hexosaminidase release (i.e., inhibitory effect on histamine release), an inhibitory effect on platelet aggregation, and an inhibitory effect on phospholipase A2 activity.
    Type: Grant
    Filed: January 15, 2010
    Date of Patent: October 22, 2013
    Assignee: Maruzen Pharmaceuticals Co., Ltd.
    Inventors: Yasuo Miyake, Ito Yoko
  • Patent number: 7910557
    Abstract: A substance having a testosterone 5?-reductase inhibiting action, a hair papilla cell growth promoting action, a fibroblast growth factor-7 production promoting action, a vascular endothelial growth factor production promoting action or a bone morphogenetic protein-2 production promoting action, and a hair care product having this substance blended therein. A hair growth tonic, a testosterone 5?-reductase inhibitor, a hair papilla cell growth promoter, a fibroblast growth factor-7 production promoter, a vascular endothelial growth factor production promoter and a bone morphogenetic protein-2 production promoter each having this substance, such as corosolic acid, as an active ingredient thereof.
    Type: Grant
    Filed: September 22, 2009
    Date of Patent: March 22, 2011
    Assignee: Maruzen Pharmaceuticals Co., Ltd.
    Inventors: Jun Nojima, Yasuo Miyake, Nobuaki Ohto
  • Publication number: 20100048703
    Abstract: A substance having a testosterone 5?-reductase inhibiting action, a hair papilla cell growth promoting action, a fibroblast growth factor-7 production promoting action, a vascular endothelial growth factor production promoting action or a bone morphogenetic protein-2 production promoting action, and a hair care product having this substance blended therein. A hair growth tonic, a testosterone 5?-reductase inhibitor, a hair papilla cell growth promoter, a fibroblast growth factor-7 production promoter, a vascular endothelial growth factor production promoter and a bone morphogenetic protein-2 production promoter each having this substance, such as corosolic acid, as an active ingredient thereof.
    Type: Application
    Filed: September 22, 2009
    Publication date: February 25, 2010
    Applicant: MARUZEN PHARMACEUTICALS CO., LTD
    Inventors: Jun Nojima, Yasuo Miyake, Nobuaki Ohto
  • Publication number: 20090054522
    Abstract: With an object of discovering a substance having a testosterone 5?-reductase inhibiting action, a hair papilla cell growth promoting action, a fibroblast growth factor-7 production promoting action, a vascular endothelial growth factor production promoting action or a bone morphogenetic protein-2 production promoting action, and of providing a hair care product having this substance blended therein, and a hair growth tonic, a testosterone 5?-reductase inhibitor, a hair papilla cell growth promoter, a fibroblast growth factor-7 production promoter, a vascular endothelial growth factor production promoter and a bone morphogenetic protein-2 production promoter each having this substance as an active ingredient thereof, a hair care product of the present invention is made to contain corosolic acid therein, and each of a hair growth tonic, a testosterone 5?-reductase inhibitor, a hair papilla cell growth promoter, a fibroblast growth factor-7 production promoter, a vascular endothelial growth factor production pro
    Type: Application
    Filed: February 14, 2006
    Publication date: February 26, 2009
    Applicant: MARUZEN PHARMACEUTICALS CO., LTD.
    Inventors: Jun Nojima, Yasuo Miyake, Nobuaki Ohto
  • Patent number: 6022718
    Abstract: A method of producing a capsaicin analogue, comprising reacting a fatty acid having 12 or more carbon atoms or an ester thereof (inclusive of fats and oils) with capsaicin in the presence of lipase to produce an N-vanillyl fatty acid amide having an acyl group containing 12 or more carbon atoms, and a method of producing fats and oils containing capsaicin analogues, comprising reacting edible fats and oils with capsaicin in the presence of lipase to produce N-vanillyl fatty acid amides from a portion of the edible fats and oils are provided. It is possible to produce non-pungent capsaicin analogues and other capsaicin analogues, which facilitates utilization of non-pungent capsaicin analogues in the food industry.
    Type: Grant
    Filed: December 21, 1998
    Date of Patent: February 8, 2000
    Assignee: Maruzen Pharmaceuticals Co., Ltd.
    Inventors: Kazuo Iwai, Tatsuo Watanabe, Yukiyoshi Tamura, Susumu Ogawa
  • Patent number: 4448788
    Abstract: 11-Deoxoglycyrrhetinic acid hydrogen maleate of the following formula ##STR1## and its salts, and this compound is prepared by reacting 11-deoxoglycyrrhetinic acid with maleic anhydride, and if desired, converting the resulting 11-deoxoglycyrrhetinic acid hydrogen maleate to its salt. The compound is useful as medicament for treating an ulcer or inflammation in man or another animal or activating the cellular immunity of man or the animal.
    Type: Grant
    Filed: July 1, 1982
    Date of Patent: May 15, 1984
    Assignee: Maruzen Pharmaceutical Co., Ltd.
    Inventors: Shigeshi Toyoshima, Hajime Fujimura, Shunsuke Ito, Yasuji Kondo