Patents Assigned to Maruzen Pharmaceuticals Co., Ltd.
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Patent number: 10111920Abstract: Provided are: a production method for salt-free miso, in which steamed soy beans and koji are pressurized, heated, and fermented; salt-free miso obtained by said production method; and a hepatic function improvement agent and a hypertension improvement agent that contain said salt-free miso as an effective component thereof.Type: GrantFiled: January 6, 2015Date of Patent: October 30, 2018Assignees: MARUZEN PHARMACEUTICALS CO., LTD., MASUYAMISO CO., LTD.Inventors: Tatsuo Nakahara, Takashi Kawano
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Publication number: 20170100444Abstract: Provided are: a production method for salt-free miso, in which steamed soy beans and koji are pressurized, heated, and fermented; salt-free miso obtained by said production method; and a hepatic function improvement agent and a hypertension improvement agent that contain said salt-free miso as an effective component thereof.Type: ApplicationFiled: January 6, 2015Publication date: April 13, 2017Applicants: MARUZEN PHARMACEUTICALS CO., LTD., MASUYAMISO CO., LTD.Inventors: Tatsuo NAKAHARA, Takashi KAWANO
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Patent number: 8828955Abstract: The invention aims at finding a highly-safe natural product having glutathione production-enhancing activity, and providing a glutathione production enhancer and a prophylactic/therapeutic agent for diseases caused by glutathione deficiency using that natural product as an active ingredient. The glutathione production enhancer or the prophylactic/therapeutic agent for diseases caused by glutathione deficiency contains, as an active ingredient, a licorice extract composition that contains liquiritin, liquiritigenin, isoliquiritin and isoliquiritigenin but contains substantially no glycyrrhizic acid.Type: GrantFiled: May 1, 2009Date of Patent: September 9, 2014Assignee: Maruzen Pharmaceuticals Co., Ltd.Inventors: Nobuaki Ohto, Toshiyuki Murakami, Hirokazu Ohno
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Patent number: 8563054Abstract: An anti-inflammatory agent which includes an oil-soluble licorice extract, prepared by subjecting at least one of a leguminous plant of the genus Glycyrrhiza and a water extraction residue of a leguminous plant of the genus Glycyrrhiza to an extraction treatment with an organic solvent and which has at least one effect selected from an inhibitory effect on hyaluronidase activity, an inhibitory effect on hexosaminidase release (i.e., inhibitory effect on histamine release), an inhibitory effect on platelet aggregation, and an inhibitory effect on phospholipase A2 activity.Type: GrantFiled: January 15, 2010Date of Patent: October 22, 2013Assignee: Maruzen Pharmaceuticals Co., Ltd.Inventors: Yasuo Miyake, Ito Yoko
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Patent number: 7910557Abstract: A substance having a testosterone 5?-reductase inhibiting action, a hair papilla cell growth promoting action, a fibroblast growth factor-7 production promoting action, a vascular endothelial growth factor production promoting action or a bone morphogenetic protein-2 production promoting action, and a hair care product having this substance blended therein. A hair growth tonic, a testosterone 5?-reductase inhibitor, a hair papilla cell growth promoter, a fibroblast growth factor-7 production promoter, a vascular endothelial growth factor production promoter and a bone morphogenetic protein-2 production promoter each having this substance, such as corosolic acid, as an active ingredient thereof.Type: GrantFiled: September 22, 2009Date of Patent: March 22, 2011Assignee: Maruzen Pharmaceuticals Co., Ltd.Inventors: Jun Nojima, Yasuo Miyake, Nobuaki Ohto
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Publication number: 20100048703Abstract: A substance having a testosterone 5?-reductase inhibiting action, a hair papilla cell growth promoting action, a fibroblast growth factor-7 production promoting action, a vascular endothelial growth factor production promoting action or a bone morphogenetic protein-2 production promoting action, and a hair care product having this substance blended therein. A hair growth tonic, a testosterone 5?-reductase inhibitor, a hair papilla cell growth promoter, a fibroblast growth factor-7 production promoter, a vascular endothelial growth factor production promoter and a bone morphogenetic protein-2 production promoter each having this substance, such as corosolic acid, as an active ingredient thereof.Type: ApplicationFiled: September 22, 2009Publication date: February 25, 2010Applicant: MARUZEN PHARMACEUTICALS CO., LTDInventors: Jun Nojima, Yasuo Miyake, Nobuaki Ohto
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Publication number: 20090054522Abstract: With an object of discovering a substance having a testosterone 5?-reductase inhibiting action, a hair papilla cell growth promoting action, a fibroblast growth factor-7 production promoting action, a vascular endothelial growth factor production promoting action or a bone morphogenetic protein-2 production promoting action, and of providing a hair care product having this substance blended therein, and a hair growth tonic, a testosterone 5?-reductase inhibitor, a hair papilla cell growth promoter, a fibroblast growth factor-7 production promoter, a vascular endothelial growth factor production promoter and a bone morphogenetic protein-2 production promoter each having this substance as an active ingredient thereof, a hair care product of the present invention is made to contain corosolic acid therein, and each of a hair growth tonic, a testosterone 5?-reductase inhibitor, a hair papilla cell growth promoter, a fibroblast growth factor-7 production promoter, a vascular endothelial growth factor production proType: ApplicationFiled: February 14, 2006Publication date: February 26, 2009Applicant: MARUZEN PHARMACEUTICALS CO., LTD.Inventors: Jun Nojima, Yasuo Miyake, Nobuaki Ohto
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Patent number: 6022718Abstract: A method of producing a capsaicin analogue, comprising reacting a fatty acid having 12 or more carbon atoms or an ester thereof (inclusive of fats and oils) with capsaicin in the presence of lipase to produce an N-vanillyl fatty acid amide having an acyl group containing 12 or more carbon atoms, and a method of producing fats and oils containing capsaicin analogues, comprising reacting edible fats and oils with capsaicin in the presence of lipase to produce N-vanillyl fatty acid amides from a portion of the edible fats and oils are provided. It is possible to produce non-pungent capsaicin analogues and other capsaicin analogues, which facilitates utilization of non-pungent capsaicin analogues in the food industry.Type: GrantFiled: December 21, 1998Date of Patent: February 8, 2000Assignee: Maruzen Pharmaceuticals Co., Ltd.Inventors: Kazuo Iwai, Tatsuo Watanabe, Yukiyoshi Tamura, Susumu Ogawa
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Patent number: 4448788Abstract: 11-Deoxoglycyrrhetinic acid hydrogen maleate of the following formula ##STR1## and its salts, and this compound is prepared by reacting 11-deoxoglycyrrhetinic acid with maleic anhydride, and if desired, converting the resulting 11-deoxoglycyrrhetinic acid hydrogen maleate to its salt. The compound is useful as medicament for treating an ulcer or inflammation in man or another animal or activating the cellular immunity of man or the animal.Type: GrantFiled: July 1, 1982Date of Patent: May 15, 1984Assignee: Maruzen Pharmaceutical Co., Ltd.Inventors: Shigeshi Toyoshima, Hajime Fujimura, Shunsuke Ito, Yasuji Kondo