Patents Assigned to Masami Tsuboshima
  • Prostaglandin derivatives
    Patent number: 4812457
    Abstract: Permeability characterized in that the carboxy group at 1-position of the prostaglandin is combined with a cell membrane permeable substance having hydroxy group or amino group through the intermediation of an ester bond to the hydroxy group or an amide bond to the amino group are novel and have improved cell membrane permeability.
    Type: Grant
    Filed: January 29, 1988
    Date of Patent: March 14, 1989
    Assignees: Research Development Corporation, Masami Tsuboshima
    Inventors: Shuh Narumiya, Osamu Hayaishi, Yoshiharu Kimura, Masami Tsuboshima