Patents Assigned to Masaryk Memorial Cancer Institute
  • Therapeutic applications of p53 isoforms in regenerative medicine, aging and cancer
    Patent number: 9944927
    Abstract: The present invention provides methods and compositions for modulating cell senescence and cell proliferation using isoforms of the p53 tumor suppressor protein. The methods and compositions of the invention find use in inhibiting cancer cell growth or in generating populations of cells for tissue regeneration through the modulation of cell senescence and proliferation.
    Type: Grant
    Filed: June 29, 2015
    Date of Patent: April 17, 2018
    Assignees: The United States of America, as represented by the Secretary, Department of Health and Human Services, The University of Dundee, Masaryk Memorial Cancer Institute
    Inventors: Curtis C. Harris, Kaori Fujita, Izumi Horikawa, Borivoj Vojtesek, Jean-Christophe Bourdon, David P. Lane
  • Therapeutic applications of P53 isoforms in regenerative medicine, aging and cancer
    Patent number: 9068165
    Abstract: The present invention provides methods and compositions for modulating cell senescence and cell proliferation using isoforms of the p53 tumor suppressor protein. The methods and compositions of the invention find use in inhibiting cancer cell growth or in generating populations of cells for tissue regeneration through the modulation of cell senescence and proliferation.
    Type: Grant
    Filed: July 26, 2013
    Date of Patent: June 30, 2015
    Assignees: The United States of America as represented by the Secretary of the Department of Health and Human Services, The University of Dundee, Masaryk Memorial Cancer Institute
    Inventors: Curtis C. Harris, Kaori Fujita, Izumi Horikawa, Borivoj Vojtesek, Jean-Christophe Bourdon, David P. Lane
  • THERAPEUTIC APPLICATIONS OF P53 ISOFORMS IN REGENERATIVE MEDICINE, AGING AND CANCER
    Publication number: 20130302892
    Abstract: The present invention provides methods and compositions for modulating cell senescence and cell proliferation using isoforms of the p53 tumor suppressor protein. The methods and compositions of the invention find use in inhibiting cancer cell growth or in generating populations of cells for tissue regeneration through the modulation of cell senescence and proliferation.
    Type: Application
    Filed: July 26, 2013
    Publication date: November 14, 2013
    Applicants: The Government of the USA as represented by the Sec. of the Dept. of Health and Human Services, Masaryk Memorial Cancer Institute, The University of Dundee
    Inventors: Curtis C. Harris, Kaori Fujita, Izumi Horikawa, Barivoj Vojtesek, Jean-Christophe Bourdon, David P. Lane
  • Therapeutic applications of p53 isoforms in regenerative medicine, aging and cancer
    Patent number: 8575121
    Abstract: The present invention provides methods and compositions for modulating cell senescence and cell proliferation using isoforms of the p53 tumor suppressor protein. The methods and compositions of the invention find use in inhibiting cancer cell growth or in generating populations of cells for tissue regeneration through the modulation of cell senescence and proliferation.
    Type: Grant
    Filed: October 21, 2008
    Date of Patent: November 5, 2013
    Assignees: The United States of America as represented by the Secetary of the Department of Health and Human Services, The University of Dundee, Masaryk Memorial Cancer Institute
    Inventors: Curtis C. Harris, Kaori Fujita, Izumi Horikawa, Borivoj Vojtesek, Jean-Christophe Bourdon, David P. Lane