Patents Assigned to Masarykova Univerzita V Brne
  • Method of production of optically active halohydrocarbons and alcohols using hydrolytic dehalogenation catalysed by haloalkane dehalogenases
    Patent number: 7632666
    Abstract: A method of production of optically active compounds, particularly halohydrocarbons, haloalcohols, alcohols, halopolyols and polyols using hydrolytic dehalogenation of racemic or prochiral halegenhydrocarbons by dehalohenation catalysed by haloalkane dehalogenases (the enzyme code number EC 3.8.1.5) where at least one wild type or modified haloalkane dehalogenase is applied to at least one racemic or prochiral chlorinated, brominated or iodinated compound at the temperature ranged between +10 and +70° C. and pH value between 4.0 and 12.0, in aqueous system or in a monophasic organic solution or in a monophasic organic/aqueous solution or in organic/aqueous biphasic systems.
    Type: Grant
    Filed: August 24, 2007
    Date of Patent: December 15, 2009
    Assignee: Masarykova Univerzita V Brne
    Inventors: Zbynek Prokop, Jiri Damborsky, Dick B. Janssen, Yuji Nagata
  • Method of Production of Optically Active Halohydrocarbons and Alcohols Using Hydrolytic Dehalogenation Catalysed by Haloalkanedehalogenases
    Publication number: 20090155868
    Abstract: A method of production of optically active compounds, particularly halohydrocarbons, haloalcohols, alcohols, halopolyols and polyols using hydrolytic dehalogenation of racemic or prochiral halegenhydrocarbons by dehalohenation catalysed by haloalkane dehalogenases (EC 3.8.1.5) where at least one wild type or modified haloalkane dehalogenase is affected by at least one racemic or prochiral chlorinated, brominated or iodinated compound at the temperature ranged between +10 and +70° C. and pH value between 4.0 and 12.0, in aqueous system or in a monophasic organic solution or in a monophasic organic/aqueous solution or in organic/aqueous biphasic systems.
    Type: Application
    Filed: December 23, 2005
    Publication date: June 18, 2009
    Applicant: MASARYKOVA UNIVERZITA V BRNE
    Inventors: Zbynek Prokop, Jiri Damborsky, Dick B. Janssen, Yuji Nagata
  • METHOD OF PRODUCTION OF OPTICALLY ACTIVE HALOHYDROCARBONS AND ALCOHOLS USING HYDROLYTIC DEHALOGENATION CATALYSED BY HALOALKANE DEHALOGENASES
    Publication number: 20080102501
    Abstract: A method of production of optically active compounds, particularly halohydrocarbons, haloalcohols, alcohols, halopolyols and polyols using hydrolytic dehalogenation of racemic or prochiral halegenhydrocarbons by dehalohenation catalysed by haloalkane dehalogenases (the enzyme code number EC 3.8.1.5) where at least one wild type or modified haloalkane dehalogenase is applied to at least one racemic or prochiral chlorinated, brominated or iodinated compound at the temperature ranged between +10 and +70° C. and pH value between 4.0 and 12.0, in aqueous system or in a monophasic organic solution or in a monophasic organic/aqueous solution or in organic/aqueous biphasic systems.
    Type: Application
    Filed: August 24, 2007
    Publication date: May 1, 2008
    Applicant: MASARYKOVA UNIVERZITA V BRNE
    Inventors: Zbynek PROKOP, Jiri DAMBORSKY, Dick JANSSEN, Yuji NAGATA