Abstract: Embodiments of a method, a system, and non-transitory computer readable storage media evaluating electrochemical qualities for interphase products. The disclosed embodiments perform a selection of a plurality of chemical phases for a solid electrolyte and at least one of the anode and cathode to be received. Thermodynamic data is received for the plurality of chemical phases. The retrieved thermodynamic data is received to evaluate a respective electrochemical quality for at least one of an interface between the solid electrolyte and the anode, and an interface between the solid electrolyte and the cathode.

Abstract: An electrochemical cell includes a negative electrode comprising a first active metal, a positive electrode comprising a second active metal, and an electrolyte comprising salts of the two active metals, a salt of the cathodic metal and a salt of the anodic metal. In operation, the electrolyte composition varies such that in a charging mode the salt of the anodic salt decreases, while the salt of the cathodic salt increases, and in a discharging mode the salt of the anodic salt increases, while the salt of the cathodic salt decreases. The cell is operational for both storing electrical energy and as a source of electrical energy as part of an uninterruptible power system. The cell is particularly suited to store electrical energy produced by an intermittent renewable energy source.

Abstract: Digital compensators for use in outphasing-based power amplification systems (e.g., Linear Amplification using Nonlinear Components (LINC) amplifiers and Asymmetric Multilevel Outphasing (AMO) amplifiers) include a short memory nonlinear portion and a long memory linear time invariant (LTI) portion. In various embodiments, compensators are provided that are of relatively low complexity and that are capable of operation at throughputs exceeding a Gigasample per second.

Abstract: An encoder generates a compressed data sequence from an original data sequence using many-to-one mapping independently of a source model associated with the original data sequence and without extracting the source model. A decoder uses both the source model associated with the original data sequence and the mapping applied during compression that is devoid of, in substance, the source model, to regenerate, at least in part, the original uncompressed data sequence from the compressed data sequence that does not include a significant portion of the source model.

Abstract: In one aspect, a method to generate an attack graph includes determining if a potential node provides a first precondition equivalent to one of preconditions provided by a group of preexisting nodes on the attack graph. The group of preexisting nodes includes a first state node, a first vulnerability instance node, a first prerequisite node, and a second state node. The method also includes, if the first precondition is equivalent to one of the preconditions provided by the group of preexisting nodes, coupling a current node to a preexisting node providing the precondition equivalent to the first precondition using a first edge and if the first precondition is not equivalent to one of the preconditions provided by the group of preexisting nodes, generating the potential node as a new node on the attack graph and coupling the new node to the current node using a second edge.

Abstract: The systems and methods disclosed herein are generally related to a cell culture system. More particularly, the systems and methods enable the culturing and interconnecting of a plurality of tissue types in a biomimetic environment. By culturing organ specific tissue types within a biomimetic environment and interconnecting each of the organ systems in a physiologically meaningful way, experiments can be conducted on in vitro cells that substantially mimic the responses of in vivo cell populations. In some implementations, the organ systems are fluidically connected with a constant-volume pump.

Abstract: An optical material system for nanopatterning is provided that includes one or more material systems having spectrally selective reversible and irreversible transitions by saturating one of the spectrally selective reversible transitions with an optical node retaining a single molecule in a configuration and exposing the single molecule to its spectrally irreversible transitions to form a pattern.

Abstract: An adhesive article includes a biocompatible and at least partially biodegradable substrate having a surface; and a plurality of protrusions extending from the surface. The protrusions include a biocompatible and at least partially biodegradable material, and have an average height of less than approximately 1,000 micrometers.

Abstract: A method of making a metal oxide nanoparticle comprising contacting an aqueous solution of a metal salt with an oxidant. The method is safe, environmentally benign, and uses readily available precursors. The size of the nanoparticles, which can be as small as 1 nm or smaller, can be controlled by selecting appropriate conditions. The method is compatible with biologically derived scaffolds, such as virus particles chosen to bind a desired material. The resulting nanoparticles can be porous and provide advantageous properties as a catalyst.

Abstract: An apparatus for detecting electromagnetic radiation within a target frequency range is provided. The apparatus includes a substrate and one or more resonator structures disposed on the substrate. The substrate can be a dielectric or semiconductor material. Each of the one or more resonator structures has at least one dimension that is less than the wavelength of target electromagnetic radiation within the target frequency range, and each of the resonator structures includes at least two conductive structures separated by a spacing. Charge carriers are induced in the substrate near the spacing when the resonator structures are exposed to the target electromagnetic radiation. A measure of the change in conductivity of the substrate due to the induced charge carriers provides an indication of the presence of the target electromagnetic radiation.

Abstract: The disclosure is generally directed to fabrication steps, and operation principles for microelectromechanical (MEMS) transducers. In one embodiment, the disclosure relates to a texture morphing device. The texture morphing device includes: a plurality of supports arranged on a substrate to support a deformable mirror; an ITO layer; and a Distributed Bragg Reflector (DBR) layer. A pair of adjacent supports form a cavity with the ITO layer and the deformable mirror. When the height of the cavity changes responsive to an external pressure, the internal reflection within the cavity is changed. The change in the height of the cavity causes the exterior texture to morph. Similar principles are disclosed for constructing sensor and actuators.

Abstract: A control system for improving and stabilizing Fourier domain mode locking (FDML) operation. The control system may also provide regulation of FDML operational parameters such as filter tuning, laser gain, polarization, polarization chromaticity, elliptical polarization retardance, and/or dispersion. The control system may be located internal to or external from the FDML laser cavity.

Abstract: A method, apparatus and computer program product for using advertisements as keys for streaming protected content is presented. Protected content is received at a user computer system, wherein the protected content is not viewable by the user. Appended content, such as an advertisement, is also received at the user computer system. The user views the appended content, wherein the viewing of the appended content results in the protected content being viewable by the user. The user then views the protected content.

Abstract: Devices and methods for providing electrochemical actuation are described herein. In one embodiment, an actuator device includes an electrochemical cell including a negative electrode and a positive electrode At least a portion of the negative electrode is formed with a material formulated to at least one of intercalate, de-intercalate, alloy with, oxidize, reduce, or plate with a first portion of the positive electrode to an extent different than with a second portion of the positive electrode such that a differential strain is imparted between the first portion and the second portion of the positive electrode and such that at least a portion of the electrochemical cell is displaced. The electrochemical cell includes a portion that is pre-bent along an axis of the electrochemical cell to define a fold axis and the displacement of the at least a portion of the electrochemical cell is maximized along the fold axis.

Abstract: The invention relates to nucleic acid molecules and compositions for specific post-transcriptional inhibition of PKM2 expression. Methods for specific inhibition of PKM2 expression in a target cell, for example a cancer cell, are also provided.

Abstract: The present invention provides compositions and methods for noninvasive delivery of therapeutic agents across an intact tympanic membrane. For example, the compositions include a penetration enhancer which increases the flux of a therapeutic agent (e.g., antibiotic) across the tympanic membrane. Such compositions are particularly useful in the treatment of otitis media. Additionally, the composition may include a sustained release agents that, in some embodiments form sustained release reservoirs, in situ, once administered to a patient.

Abstract: The invention provides compositions and methods for treating cancer. Aspects of the invention relate to therapeutic compositions comprising tolperisone and related compounds. Aspects of the invention relate to methods and compositions for treating Ras-associated cancers.

Abstract: Two distinct scavenger receptor type proteins having high affinity for modified lipoproteins and other ligands have been isolated, characterized and cloned. HaSR-BI, an AcLDL and LDL binding scavenger receptor, which is distinct from the type I and type II macrophage scavenger receptors, has been isolated and characterized and DNA encoding the receptor cloned from a variant of Chinese Hamster Ovary Cells, designated Var-261. dSR-CI, a non-mammalian AcLDL binding scavenger receptor having high ligand affinity and broad specificity, was isolated from Drosophila melanogaster. The isolated receptors are useful in screening for drugs that inhibit uptake of cholesterol in endothelial or adipose cells or macrophages, respectively. They are also useful as probes for the isolation of other lipoprotein receptors and in research the roles of these receptors.

Abstract: One aspect of the present invention relates to magnetophoretic devices for cell clarification. In one embodiment, the magnetophoretic device is a counter-current device, comprising a plurality of pairs of magnets selected from the group consisting of permanent magnets and electromagnets; a chain rotated by a motor; tubing; a feed inlet; and a clarified feed outflow. In another embodiment, the magnetophoretic device is a quadrupole device, comprising four magnets selected from the group consisting of permanent magnets and electromagnets; and a cylindrical column. Another aspect of the invention relates generally to a method of separating non-magnetic particles from a magnetic fluid mixture, comprising the steps of combining a magnetic fluid with a sample comprising non-magnetic particles and non-magnetic fluid to form a mixture; subjecting said mixture to a degrading magnetic field; and isolating a portion of the non-magnetic particles from said mixture.

Abstract: An impact absorber using an energy-absorbing, fluid-impregnated material consisting of a porous interconnected network of solid material forming edges and faces of cells, preferably an open-cell reticulated or partially closed-cell foam, or formed from fibers or other cellular solids. The matrix is impregnated with a field responsive fluid such as a magneto- or electro-rheological fluid, or with a shear-rate responsive fluid such as a dilatant (shear-thickening) fluid. The material is placed under compression during impact, and may be housed within a cylinder and compressed by a piston. The stiffness of the composite material consisting of a matrix filled with a field responsive fluid can be controlled by varying the field intensity and spatial gradients of the applied field to vary the rheological properties of the fluid.