Abstract: A method and an apparatus are disclosed for using quasielastic light scattering to determine the degree of cataractogenesis of a lens in vivo. By collecting and analyzing light scattered from the lens, it is possible, using the temporal autocorrelation function, to produce a signature of cataractogenesis, accounting for scattering due to substantially immobile scatterers. The component of the temporal autocorrelation function representing the effect of the substantially immobile scatterers is expressed as a function of the measurement delay time. The components of the cataractogenesis can also be detected by comparing the values of the components of the signature of cataractogenesis to frequency distribution of the components taken from populations or by detecting changes in the values of the components of the signature of cataractogenesis as a function of time.
Type:
Grant
Filed:
November 9, 1993
Date of Patent:
June 27, 1995
Assignee:
Massachusetts Institute of Technology Oculon Corporation
Inventors:
George M. Thurston, Douglas L. Hayden, George B. Benedek