Patents Assigned to Massachusetts Institute Technology
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Publication number: 20240014577Abstract: Described is an in-band full-duplex (IBFD) antenna having direction finding capability. The IBFD antenna includes a transmit antenna having an omnidirectional radiation pattern and a receive antenna configured to provide a plurality of difference beams. The IBFD antenna may be disposed on a moving platform to cover all angles around the moving platform.Type: ApplicationFiled: July 11, 2023Publication date: January 11, 2024Applicant: Massachusetts Institute of TechnologyInventors: Kenneth E. KOLODZIEJ, David M. BRAGDON, Pierre A. DUFILIE, William F. MOULDER, Bradley Thomas PERRY
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Publication number: 20240011002Abstract: The invention relates, in part, to methods of preparing male organisms of a species that include engineering the male organisms in a manner that eliminates post-embryonic viability of the female offspring and female descendants of the engineered male organisms. Certain aspects of the invention include use of such prepared engineered male organisms in methods of controlling population levels of organisms of the species.Type: ApplicationFiled: October 8, 2020Publication date: January 11, 2024Applicant: Massachusetts Institute of TechnologyInventor: Kevin Michael ESVELT
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Publication number: 20240013960Abstract: A magnet system and method of operating may be used in connection with operating a superconducting electromagnet, for example in a tokamak. The magnet system includes a coil having windings retained within a non-insulated structure, so that current can pass both along the windings to generate a magnetic field, and between the windings. The amount of current passing through the coil is trimmed using a bypass circuit, coupled in parallel to the coil terminals. The bypass circuit is controlled on the basis of measurements of the field components to divert current from passing through the field coil. In this way, the magnetic fields of each of multiple field coils can be brought into mutual uniformity.Type: ApplicationFiled: March 1, 2021Publication date: January 11, 2024Applicants: Massachusetts Institute of Technology, Commonwealth Fusion Systems LLCInventors: Alexey RADOVINSKY, Robert MUMGAARD, Theodore GOLFINOPOULOS
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Publication number: 20240013933Abstract: Described are concepts, structures and techniques for passive mitigation of relativistic electrons produced in a tokamak plasma. These electrons may be referred to herein as “runaway” electrons (REs). In embodiments, a passive runaway electron mitigation coil (REMC) comprises an electrical conductor having a non-axisymmetric loop shape comprising a plurality of portions arranged along paths defined by the surface of a torus along a toroidal direction. In operation, the REMC is energized by a disruption-induced voltage, and the resulting magnetic field stochasticity causes electrons to be lost more rapidly than a RE beam can form. The REMC is configured for outboard side mounting within a vacuum vessel.Type: ApplicationFiled: June 10, 2021Publication date: January 11, 2024Applicant: Massachusetts Institute of TechnologyInventors: Darren T. GARNIER, Robert S. GRANETZ, Ryan M. SWEENEY
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Publication number: 20240013084Abstract: A scalable point defect qubit control system may include a diamond waveguide array comprising one or more diamond waveguides and a microwave line disposed proximally to the diamond waveguide array. Each diamond waveguide in the diamond waveguide array may include one or more qubits encoded in point defect sites. The microwave line may be configured to receive a direct current (DC) signal configured to shift an energy level of each point defect qubit of the one or more point defect qubits based on a position of the point defect in the diamond waveguide array, and receive an alternating current (AC) signal configured to control a quantum state of a point defect qubit of the one or more point defect qubits, wherein one or more properties of the AC signal are based on the shift in the energy level induced by the DC signal.Type: ApplicationFiled: April 26, 2023Publication date: January 11, 2024Applicants: The MITRE Corporation, National Technology & Engineering Solution of Sandia, LLC, MIT - Massachusetts Institute of TechnologyInventors: Andrew GOLTER, Genevieve CLARK, Tareq EL DANDACHI, Stefan KRASTANOV, Matthew ZIMMERMANN, Andrew GREENSPON, Noel WAN, Hamza RANIWALA, Kevin CHEN, Linsen LI, Andrew LEENHEER, Mark DONG, Gerald GILBERT, Matthew EICHENFIELD, Dirk ENGLUND
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Patent number: 11866697Abstract: The invention provides for systems, methods, and compositions for targeting and editing nucleic acids. In particular, the invention provides non-naturally occurring or engineered DNA-targeting systems comprising a DNA-targeting Cpf1 protein, at least one guide molecule, and at least one adenosine deaminase protein or catalytic domain thereof.Type: GrantFiled: May 18, 2018Date of Patent: January 9, 2024Assignees: THE BROAD INSTITUTE, INC., MASSACHUSETTS INSTITUTE OF TECHNOLOGY, PRESIDENT AND FELLOWS OF HARVARD COLLEGEInventors: Feng Zhang, David Benjamin Turitz Cox, Jonathan Gootenberg, Omar O. Abudayyeh, Bernd Zetsche, Jonathan Strecker
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Patent number: 11868051Abstract: Conventional optical lithography uses masks with static patterns that are expensive and labor intensive to produce. The present disclosure is directed to a programmable optical lithography mask with an array of cells that use a hydrogen-mediated mechanism to tune their optical properties (e.g., transmission, absorption, refractive index, and/or reflectivity) dynamically and reversibly. Each cell in the programmable mask may be individually addressable to produce a large variety of patterns. The programmable mask may be configured for ultra-fine spatial resolution or coarse spatial resolution, facilitating a wide range of applications. The programmable mask may be stable against short wavelength light, such as broadband ultraviolet (UV) light, and can thus act as a light valve for short wavelength light.Type: GrantFiled: April 2, 2021Date of Patent: January 9, 2024Assignee: Massachusetts Institute of TechnologyInventors: Aik Jun Tan, Mantao Huang, Geoffrey S. D. Beach
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Patent number: 11866670Abstract: Systems and methods associated with biomass decomposition are generally described. Certain embodiments are related to adjusting a flow rate of a fluid comprising oxygen into a reactor in which biomass is decomposed. The adjustment may be made, at least in part, based upon a measurement of a characteristic of the reactor and/or a characteristic of the biomass. Certain embodiments are related to cooling at least partially decomposed biomass. The biomass may be cooled by flowing a gas over an outlet conduit in which the biomass is cooled, and then directing the gas to a reactor after it has flowed over the outlet conduit. Certain embodiments are related to systems comprising a reactor and an outlet conduit configured such that greater than or equal to 75% of its axially projected cross-sectional area is occupied by a conveyor.Type: GrantFiled: April 28, 2022Date of Patent: January 9, 2024Assignee: Massachusetts Institute of TechnologyInventors: Kevin S. Kung, Alexander H. Slocum, Santosh Janardhan Shanbhogue, Ahmed Fouad Ghoniem, Robert James Stoner
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Patent number: 11866629Abstract: A semiconductor nanocrystal can be made by an in situ redox reaction between an M donor and an E donor.Type: GrantFiled: January 12, 2021Date of Patent: January 9, 2024Assignee: Massachusetts Institute of TechnologyInventors: Moungi Bawendi, Daniel Franke, Matthias Ginterseder
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Patent number: 11865168Abstract: Provided herein are compositions and methods for therapeutic and/or prophylactic treatment of an intracellular bacterial infection in a subject in need thereof, comprising one or more modulating agents, wherein the one or more modulating agents increase expression of IFN?, IL-2, TNF, and/or IL-17 in systemic and/or lung T cells. In some embodiments, the increase of expression of IFN?, IL-2, TNF, and/or IL-17 occurs in lung T cells. The lung T cells can be lung resident T cells or systemic T cells that are recruited to the lung. In some embodiments, the T cells are CD4+ and/or CD8+ T cells. In some embodiments, the intracellular bacterial infection is a Mycobacterium tuberculosis (MTB) infection.Type: GrantFiled: December 30, 2020Date of Patent: January 9, 2024Assignees: Massachusetts Institute of Technology, The United States of America, as represented by The Secretary, Department of Health & Human Services, University of Pittsburgh—Of The Commonwealth System of Higher EducationInventors: Alexander K. Shalek, Travis Hughes, Marc H. Wadsworth, Robert Seder, Mario Roederer, Joanne L. Flynn, Patricia Darrah
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Patent number: 11870459Abstract: Described is a decoder suitable for use with any communication or storage system. The described decoder has a modular decoder hardware architecture capable of implementing a noise guessing process and due to its dependency only on noise, the decoder design is independent of any encoder, thus making it a universal decoder. Hence, the decoder architecture described herein is agnostic to any coding scheme.Type: GrantFiled: April 8, 2021Date of Patent: January 9, 2024Assignees: Massachusetts Institute of Technology, National University of Ireland Maynooth, Trustees of Boston UniversityInventors: Amit Solomon, Muriel Medard, Kenneth R. Duffy, Rabia Tugce Yazicigil Kirby, Vaibhav Bansal, Wei An
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Publication number: 20240005627Abstract: A method of conditional neural ground planes for static-dynamic disentanglement is described. The method includes extracting, using a convolutional neural network (CNN), CNN image features from an image to form a feature tensor. The method also includes resampling unprojected 2D features of the feature tensor to form feature pillars. The method further includes aggregating the feature pillars to form an entangled neural ground plane. The method also includes decomposing the entangled neural ground plane into a static neural ground plane and a dynamic neural ground plane.Type: ApplicationFiled: April 18, 2023Publication date: January 4, 2024Applicants: TOYOTA RESEARCH INSTITUTE, INC., TOYOTA JIDOSHA KABUSHIKI KAISHA, MASSACHUSETTS INSTITUTE OF TECHNOLOGYInventors: Prafull SHARMA, Ayush TEWARI, Yilun DU, Sergey ZAKHAROV, Rares Andrei AMBRUS, Adrien David GAIDON, William Tafel FREEMAN, Frederic Pierre DURAND, Joshua B. TENENBAUM, Vincent SITZMANN
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Publication number: 20240002986Abstract: Iron-containing alloys, and associated systems and methods, are generally described. The iron-containing alloys are, according to certain embodiments, nanocrystalline. According to certain embodiments, the iron-containing alloys have high relative densities. The iron-containing alloys can be relatively stable, according to certain embodiments. Inventive methods for making iron-containing alloys are also described herein. The inventive methods for making iron-containing alloys can involve, according to certain embodiments, sintering nanocrystalline particulates comprising iron and at least one other element (e.g., at least one other metal or a metalloid) to form an iron-containing nanocrystalline alloy.Type: ApplicationFiled: May 12, 2023Publication date: January 4, 2024Applicant: Massachusetts Institute of TechnologyInventors: Dor Amram, Christopher A. Schuh
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Patent number: 11860458Abstract: A spatial light modulator (SLM) comprised of a 2D array of optically-controlled semiconductor nanocavities can have a fast modulation rate, small pixel pitch, low pixel tuning energy, and millions of pixels. Incoherent pump light from a control projector tunes each PhC cavity via the free-carrier dispersion effect, thereby modulating the coherent probe field emitted from the cavity array. The use of high-Q/V semiconductor cavities enables energy-efficient all-optical control and eliminates the need for individual tuning elements, which degrade the performance and limit the size of the optical surface. Using this technique, an SLM with 106 pixels, micron-order pixel pitch, and GHz-order refresh rates could be realized with less than 1 W of pump power.Type: GrantFiled: March 29, 2021Date of Patent: January 2, 2024Assignee: Massachusetts Institute of TechnologyInventors: Christopher Louis Panuski, Dirk Robert Englund
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Patent number: 11861437Abstract: A method of detecting a stimulus can include detecting an output from a radio frequency identification tag including a sensor. A smartphone-based sensing strategy can use chemiresponsive nanomaterials integrated into the circuitry of commercial Near Field Communication tags to achieve non-line-of-sight, portable, and inexpensive detection and discrimination of gas phase chemicals (e.g., ammonia, hydrogen peroxide, cyclohexanone, and water) at part-per-thousand and part-per-million concentrations.Type: GrantFiled: December 17, 2018Date of Patent: January 2, 2024Assignee: Massachusetts Institute of TechnologyInventors: Timothy Manning Swager, Joseph Michael Azzarelli, Jens Bomholdt Ravnsbæk, Katherine Andrea Mirica
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Patent number: 11858993Abstract: Described herein are multi-specific binding agents that bind A33 and 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid. Also provided herein are methods of using multi-specific binding agents or compositions thereof for the detection, prevention, and/or therapeutic treatment of diseases characterized by expression of the A33 glycoprotein antigen, in particular, colorectal cancer.Type: GrantFiled: April 13, 2021Date of Patent: January 2, 2024Assignees: Memorial Sloan Kettering Cancer Center, Massachusetts Institute of TechnologyInventors: Sarah Cheal, Hong Xu, Steven Larson, Nai-Kong Cheung, Karl Dane Wittrup, Alice Tzeng
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Patent number: 11857919Abstract: Methods, apparatuses, and systems related to electrochemical capture of Lewis acid gases from fluid mixtures are generally described. Certain embodiments are related to electrochemical methods involving selectively removing a first Lewis acid gas from a fluid mixture containing multiple types of Lewis acid gases (e.g., a first Lewis acid gas and a second Lewis acid gas). Certain embodiments are related to electrochemical systems comprising certain types of electroactive species having certain redox states in which the species is capable of binding a first Lewis acid gas but for which binding with a second Lewis acid gas is thermodynamically and/or kinetically unfavorable. The methods, apparatuses, and systems described herein may be useful in carbon capture and pollution mitigation applications.Type: GrantFiled: October 22, 2021Date of Patent: January 2, 2024Assignee: Massachusetts Institute of TechnologyInventors: Sahag Voskian, Trevor Alan Hatton, Cameron G. Halliday
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Publication number: 20230416122Abstract: A device for purifying and/or concentrating a first water stream containing ionic impurities includes a first and second ion exchange membrane and a first porous membrane. The ion exchange membranes have the same charge, and a channel into which the first water stream can be directed is defined between the first and second ion exchange membranes. The channel has an inlet end and a return flow end and comprises a first and second outlet. The inlet and at least the first outlet are located on the inlet end of the channel and are separated by the first porous membrane that traverses the length of the channel between the ion exchange membranes and terminates at a return flow zone that is at least partially closed. At least part of the first water stream flows through the first porous membrane, joining a first return flow stream.Type: ApplicationFiled: September 1, 2023Publication date: December 28, 2023Applicant: Massachusetts Institute of TechnologyInventors: Jongyoon Han, Junghyo Yoon
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Publication number: 20230416303Abstract: Crystal nucleation, and associated articles, systems, and methods, are generally described.Type: ApplicationFiled: May 26, 2023Publication date: December 28, 2023Applicant: Massachusetts Institute of TechnologyInventors: Kripa K. Varanasi, Henri-Louis Girard, Caroline McCue
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Publication number: 20230419038Abstract: Described is a system and technique for identifying passages of legal precedent and assembling arguments that use this precedent. In embodiments, passages of judicial precedent are identified by taking advantage of a network of judicial citations. In embodiments, identified passages and relevant context from legal opinions are assembled into a synthetic argument that can be used to identify and/or predict relevant legal precedent. In embodiments, the system and technique may be used identify and/or predict precedent relevant to new arguments. The described the system and technique uses state-of-the-art natural language processing techniques, in particular transformer-based language models trained on a legal corpus, to identify and/or predict precedent relevant to a legal argument.Type: ApplicationFiled: June 28, 2022Publication date: December 28, 2023Applicant: Massachusetts Institute of TechnologyInventors: Robert Zev MAHARI, Alex Paul PENTLAND
