Patents Assigned to MAST BIOSURGERY
  • Publication number: 20130052236
    Abstract: The present disclosure provides a medical assembly comprising a surgical barrier aspect comprising polylactic acid, and a hydrophilic mucoadhesive aspect, wherein the surgical barrier aspect is provided on a first side of the assembly and the mucoadhesive aspect is provided on a second side of the assembly. The disclosure also relates to a medical assembly comprising a surgical barrier aspect, a short term mucoadhesive aspect, an intermediate term protein polymerization adhesive aspect, and a long term tissue ingrowth implant localization aspect. The aforementioned medical assemblies may be provided as layered sheet structures. Also provided are methods for preparing a medical assembly.
    Type: Application
    Filed: August 29, 2012
    Publication date: February 28, 2013
    Applicant: MAST BIOSURGERY
    Inventors: Joerg Tessmar, Eva Esser, Lukas Bluecher, Michael Milbocker
  • Patent number: 8349795
    Abstract: Resorbable lactide polymer thin membranes are disclosed. The thin membranes are constructed of polylactide resorbable polymers, which are engineered to be absorbed into the body relatively slowly over time in order to reduce potential negative side effects. The membranes are formed to have very thin thicknesses, for example, thicknesses between about 0.010 mm and about 0.30 mm. The membranes can be extruded from polylactide polymers having a relatively high viscosity property, can be preshaped with relatively thick portions, and can be stored in sterile packages.
    Type: Grant
    Filed: July 28, 2011
    Date of Patent: January 8, 2013
    Assignee: MAST Biosurgery AG
    Inventors: Christopher J. Calhoun, Ralph E. Holmes, Kenneth K. Kleinhenz
  • Patent number: 8048444
    Abstract: An anti-adhesion membrane is placed onto an implant introduced into a surgical site of a patient to prevent post-surgical adhesions between the implant and surrounding tissue. The implant may comprise either biological material, such as a transplanted organ, or non-biological material such as a medical device. The membrane may be applied in a variety of ways. In one example, a membrane according to the present invention is shrink-wrapped around a pace-maker. In another example, a breast implant is spray-coated or dipped with the membrane material.
    Type: Grant
    Filed: January 11, 2007
    Date of Patent: November 1, 2011
    Assignee: MAST Biosurgery AG
    Inventors: Christopher J. Calhoun, Ralph E. Holmes, G. Bryan Cornwall
  • Patent number: 8012502
    Abstract: Resorbable lactide polymer thin membranes are disclosed. The thin membranes are constructed of polylactide resorbable polymers, which are engineered to be absorbed into the body relatively slowly over time in order to reduce potential negative side effects. The membranes are formed to have very thin thicknesses, for example, thicknesses between about 0.010 mm and about 0.300 mm. The membranes can be extruded from polylactide polymers having a relatively high viscosity property, can be preshaped with relatively thick portions, and can be stored in sterile packages.
    Type: Grant
    Filed: November 9, 2007
    Date of Patent: September 6, 2011
    Assignee: MAST Biosurgery AG
    Inventors: Christopher J. Calhoun, Ralph E. Holmes, Kenneth K. Kleinhenz
  • Patent number: 7947300
    Abstract: Resorbable lactide polymer thin membranes are disclosed. The thin membranes are constructed of polylactide resorbable polymers, which are engineered to be absorbed into the body relatively slowly over time in order to reduce potential negative side effects. The membranes are formed to have very thin thicknesses, for example, thicknesses between about 0.010 mm and about 0.300 mm. The membranes can be extruded from polylactide polymers having a relatively high viscosity property, can be preshaped with relatively thick portions, and can be stored in sterile packages.
    Type: Grant
    Filed: January 16, 2007
    Date of Patent: May 24, 2011
    Assignee: MAST Biosurgery AG
    Inventors: Christopher J. Calhoun, Ralph E. Holmes, Kenneth K. Kleinhenz
  • Publication number: 20100310628
    Abstract: Precut, user-shapeable, resorbable polymer micro-membranes are disclosed. The micro-membranes are constructed of resorbable polymers, which are engineered to attenuate adhesions and to be absorbed into the body relatively slowly over time. The membranes can formed to have very thin thicknesses, for example, thicknesses between about 0.010 mm and about 0.300 mm, while maintaining adequate strength. The membranes can be extruded from polylactide polymers having a relatively high viscosity property, can be stored in sterile packages, and can be preshaped with relatively high reproducibility during implantation procedures.
    Type: Application
    Filed: June 9, 2009
    Publication date: December 9, 2010
    Applicant: MAST BIOSURGERY AG
    Inventor: Erich Graf Von Waldburg-Zeil
  • Patent number: 7767222
    Abstract: An anti-adhesion membrane is placed onto an implant introduced into a surgical site of a patient to prevent post-surgical adhesions between the implant and surrounding tissue. The implant may comprise either biological material, whcu as a transplanted organ, or non-biological material such as a medical device. The membrane may be applied in a variety of ways. In one example, a membrane according to the present invention is shrink-wrapped around a pace-maker. In another example, a breast implant is spray-coated or dipped with the membrane material.
    Type: Grant
    Filed: July 31, 2003
    Date of Patent: August 3, 2010
    Assignee: MAST Biosurgery AG
    Inventors: Christopher J. Calhoun, Ralph E. Holmes, G. Bryan Cornwall
  • Patent number: 7744915
    Abstract: An anti-adhesion membrane is placed onto an implant introduced into a surgical site of a patient to prevent post-surgical adhesions between the implant and surrounding tissue. The implant may comprise either biological material, such as a transplanted organ, or non-biological material such as a medical device. The membrane may be applied in a variety of ways. In one example, a membrane according to the present invention is shrink-wrapped around a pace-maker. In another example, a breast implant is spray-coated or dipped with the membrane material.
    Type: Grant
    Filed: January 12, 2007
    Date of Patent: June 29, 2010
    Assignee: MAST Biosurgery AG
    Inventors: Christopher J. Calhoun, Ralph E. Holmes, G. Bryan Cornwall
  • Patent number: 7704520
    Abstract: Resorbable polylactide polymer healing membranes and methods of their applications are disclosed. In a broad embodiment, the invention features methods for inducing proper tissue healing after an open heart surgery. In one embodiment, the methods includes a step of forming a patch with a healing membrane over the open pericardium to induce proper tissue healing and placement in other open heart surgery procedures to facilitate re-entry by the surgeon.
    Type: Grant
    Filed: September 10, 2003
    Date of Patent: April 27, 2010
    Assignee: MAST Biosurgery AG
    Inventor: Christopher J. Calhoun
  • Publication number: 20100003306
    Abstract: Precut, user-shapeable, resorbable polymer micro-membranes are disclosed. The micro-membranes are constructed of resorbable polymers, which are engineered to attenuate adhesions and to be absorbed into the body relatively slowly over time. The membranes can formed to have very thin thicknesses, for example, thicknesses between about 0.010 mm and about 0.300 mm, while maintaining adequate strength. The membranes can be extruded from polylactide polymers having a relatively high viscosity property, can be stored in sterile packages, and can be preshaped with relatively high reproducibility during implantation procedures.
    Type: Application
    Filed: June 8, 2009
    Publication date: January 7, 2010
    Applicant: MAST BIOSURGERY AG
    Inventor: Erich Graf Von Waldburg-Zeil
  • Publication number: 20090291106
    Abstract: A block copolymer containing a) a hydrophobic biodegradable polymer, b) a hydrophilic polymer and c) at least one reactive group for covalent binding of a surface-modifying substance d) to the hydrophilic polymer b) is disclosed. Shaped bodies are formed to consist of the block copolymer and are utilized as carriers for tissue culture and active substances and for controlled release and targeted administration of active substances.
    Type: Application
    Filed: July 17, 2009
    Publication date: November 26, 2009
    Applicant: MAST BIOSURGERY AG
    Inventors: Achim Göpferich, Jörg Tessmar, Michaela Schulz, Torsten Blunk, Antonios Mikos
  • Patent number: 7592017
    Abstract: Resorbable lactide polymer thin membranes are disclosed. The thin membranes are constructed of polylactide resorbable polymers, which are engineered to be absorbed into the body relatively slowly over time in order to reduce potential negative side effects. The membranes are formed to have very thin thicknesses, for example, thicknesses between about 0.010 mm and about 0.300 mm. The membranes can be extruded from polylactide polymers having a relatively high viscosity property, can be preshaped with relatively thick portions, and can be stored in sterile packages.
    Type: Grant
    Filed: July 31, 2003
    Date of Patent: September 22, 2009
    Assignee: MAST Biosurgery AG
    Inventors: Christopher J. Calhoun, Ralph E. Holmes, Kenneth K. Kleinhenz