Abstract: Disclosed embodiments include illustrative piezoelectric element array assemblies, methods of fabricating a piezoelectric element array assembly, and systems and methods for shearing cellular material. Given by way of non-limiting example, an illustrative piezoelectric element array assembly includes at least one piezoelectric element configured to produce ultrasound energy responsive to amplified driving pulses. A lens layer is bonded to the at least one piezoelectric element. The lens layer has a plurality of lenses formed therein that are configured to focus ultrasound energy created by single ones of the at least one piezoelectric element into a plurality of wells of a microplate disposable in ultrasonic communication with the lens layer, wherein more than one of the plurality of lenses overlie single ones of the at least one piezoelectric element.
Type:
Grant
Filed:
February 25, 2020
Date of Patent:
February 28, 2023
Assignees:
Matchstick Technologies, Inc., University of Washington
Inventors:
Karol Bomsztyk, Greg P. Darlington, Brian E. MacConaghy, Thomas J. Matula, Adam D. Maxwell
Abstract: Disclosed embodiments include illustrative piezoelectric element array assemblies, methods of fabricating a piezoelectric element array assembly, and systems and methods for shearing cellular material. Given by way of non-limiting example, an illustrative piezoelectric element array assembly includes at least one piezoelectric element configured to produce ultrasound energy responsive to amplified driving pulses. A lens layer is bonded to the at least one piezoelectric element. The lens layer has a plurality of lenses formed therein that are configured to focus ultrasound energy created by single ones of the at least one piezoelectric element into a plurality of wells of a microplate disposable in ultrasonic communication with the lens layer, wherein more than one of the plurality of lenses overlie single ones of the at least one piezoelectric element.
Type:
Grant
Filed:
January 17, 2018
Date of Patent:
October 20, 2020
Assignees:
Matchstick Technologies, Inc., University of Washington
Inventors:
Karol Bomsztyk, Greg P. Darlington, Brian E. MacConaghy, Thomas J. Matula, Adam D. Maxwell
Abstract: Disclosed embodiments include illustrative piezoelectric element array assemblies, methods of fabricating a piezoelectric element array assembly, and systems and methods for shearing cellular material. Given by way of non-limiting example, an illustrative piezoelectric element array assembly includes at least one piezoelectric element configured to produce ultrasound energy responsive to amplified driving pulses. A lens layer is bonded to the at least one piezoelectric element. The lens layer has a plurality of lenses formed therein that are configured to focus ultrasound energy created by single ones of the at least one piezoelectric element into a plurality of wells of a microplate disposable in ultrasonic communication with the lens layer, wherein more than one of the plurality of lenses overlie single ones of the at least one piezoelectric element.
Type:
Application
Filed:
February 25, 2020
Publication date:
July 2, 2020
Applicants:
Matchstick Technologies, Inc., University of Washington
Inventors:
Karol Bomsztyk, Greg P. Darlington, Brian E. MacConaghy, Thomas J. Matula, Adam D. Maxwell
Abstract: Disclosed embodiments include illustrative piezoelectric element array assemblies, methods of fabricating a piezoelectric element array assembly, and systems and methods for shearing cellular material. Given by way of non-limiting example, an illustrative piezoelectric element array assembly includes at least one piezoelectric element configured to produce ultrasound energy responsive to amplified driving pulses. A lens layer is bonded to the at least one piezoelectric element. The lens layer has a plurality of lenses formed therein that are configured to focus ultrasound energy created by single ones of the at least one piezoelectric element into a plurality of wells of a microplate disposable in ultrasonic communication with the lens layer, wherein more than one of the plurality of lenses overlie single ones of the at least one piezoelectric element.
Type:
Application
Filed:
January 17, 2018
Publication date:
July 26, 2018
Applicants:
Matchstick Technologies, Inc., University of Washington
Inventors:
Thomas J. Matula, Brian E. MacConaghy, Greg P. Darlington, Karol Bomsztyk, Adam D. Maxwell