Patents Assigned to Matregenix, Inc.
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Publication number: 20260110120Abstract: The present disclosure describes non-PFAS nanofiber barrier layers for protective clothing, including chemical and biological protective suits (CBPS). The barrier layers offer both excellent protection against various hazards and reduced physiological, psychological, and thermal stress.Type: ApplicationFiled: October 23, 2025Publication date: April 23, 2026Applicant: Matregenix, Inc.Inventors: Feng Guo, Sherif Soliman
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Publication number: 20260028753Abstract: The present disclosure describes electrospinning systems and apparatuses suitable for use in high throughput industrial settings. The disclosed systems and apparatuses may include a high voltage power supply having positive and negative electrodes; one or more spinnerets that include one or more convergent-divergent nozzles, one or more turbo canals, or a combination thereof; and a collector. The systems and apparatuses may further include one or more peristaltic pumps. In some implementations, the systems and apparatuses may be designed to produce nanofibers from multiple polymer solutions simultaneously. The collector may be an adjustable collector that is composed of multiple metal sheets. The collector may alternately be a conveyor belt collector.Type: ApplicationFiled: September 26, 2025Publication date: January 29, 2026Applicant: Matregenix, Inc.Inventor: Sherif Soliman
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Publication number: 20250161530Abstract: The present disclosure describes membranes suitable for use in soft tissue repair applications that are composed of fibrous and highly porous biodegradable materials fabricated using electrospinning and that may be surface-modified with plasma treatment or other suitable methods of surface modification. The disclosed membranes have a high surface area to volume ratio. In some implementations, use of the disclosed membranes provides a barrier that prevents the migration of soft tissue cells but is permeable to small molecules such as nutritional substances and medications. In other implementations, use of the disclosed membranes provides a scaffold to facilitate soft tissue repair by providing a suitable environment for cellular infiltration and interaction to promote tissue regeneration. Methods of fabricating the disclosed resorbable membranes for soft tissue repair applications using electrospinning are also disclosed.Type: ApplicationFiled: January 18, 2025Publication date: May 22, 2025Applicant: Matregenix, Inc.Inventor: Sherif Soliman
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Publication number: 20250032996Abstract: Electrospun poly(acrylic) acid (PAA)/poly(vinyl) alcohol PVA nanofibers and integrated filtration membranes generated therefrom are disclosed herein. The membranes are suitable for use in selectively removing heavy metals such as lead and cadmium from water. The surface of the nanofibers is preferably functionalized with one or more chelating agents. The membranes have a high removal efficiency and adsorption capacity with well-distributed high-density heavy metal adsorption sites with strong binding affinities for targeted heavy metals.Type: ApplicationFiled: September 16, 2024Publication date: January 30, 2025Applicant: Matregenix, Inc.Inventors: Sherif Soliman, Feng Guo
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Publication number: 20240278183Abstract: Electrospun poly(acrylic) acid (PAA)/poly(vinyl) alcohol PVA nanofibers and integrated filtration membranes generated therefrom are disclosed herein. The membranes are suitable for use in selectively removing heavy metals such as lead and cadmium from water. The surface of the nanofibers is preferably functionalized with one or more chelating agents. The membranes have a high removal efficiency and adsorption capacity with well-distributed high-density heavy metal adsorption sites with strong binding affinities for targeted heavy metals.Type: ApplicationFiled: April 26, 2024Publication date: August 22, 2024Applicant: Matregenix, Inc.Inventors: Sherif Soliman, Feng Guo
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Publication number: 20230219829Abstract: A novel solar-powered desalination and water purification system is disclosed herein. The system includes a nanofiber-impregnated graphene aerogel, an untreated water source, a water collection surface, and a purified water storage container. A novel photocatalytic nanofiber-impregnated graphene aerogel for desalination and photodegradation of contaminants for use in the disclosed system is also disclosed herein. The nanofiber-impregnated graphene aerogel exhibits excellent hydrophilicity, thermal insulation, and photodegradation capability, and allows for efficient solar-powered evaporation of water. The introduction of photocatalytic nanofibers into the graphene aerogel allows effective interfacial evaporation and in situ photodegradation of contaminants. The rate of water evaporation is preferably greater than 1.3 gal/ft2 per day, and the contaminant removal is preferably greater than 90%. A method of desalinating and purifying water using the disclosed system is also disclosed herein.Type: ApplicationFiled: May 24, 2021Publication date: July 13, 2023Applicant: Matregenix, Inc.Inventors: Sherif Soliman, Feng Guo
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Publication number: 20230167591Abstract: An electrospun polymer nanofibrous membrane that provides high filtering efficiency and excellent porosity is disclosed herein. The membrane may be treated with one or more antimicrobial or antiviral agents. The treatment may preferably be a coating of one or more antiviral agents on the surface of the membrane. Alternatively, one or more antiviral agents may be impregnated into the membrane. The membrane may additionally or alternatively be impregnated with one or more metal-organic frameworks (MOFs). The membrane has a high filtering efficiency and sufficient porosity to provide breathability characteristics. In some embodiments, the membrane is suitable for use in making facemasks and respirators that are highly resistant to infectious pathogens and/or other small particulates. In some embodiments, the membrane is suitable for use in HVAC applications. In some embodiments, the membrane is suitable for use in removal of VOCs and CO2 in conjunction with a carbon nanofiber membrane.Type: ApplicationFiled: September 30, 2022Publication date: June 1, 2023Applicant: Matregenix, Inc.Inventors: Sherif Soliman, Feng Guo
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Publication number: 20220378568Abstract: A tubular construct that includes a braided tube embedded therein is disclosed herein. The braided tube may be embedded between layers of the tubular construct or may alternatively be positioned flush with the inside of the tubular construct. The tubular construct is resistant to kinking and has enhanced radial strength. The braided tube reinforces the wall of the tubular construct by improving burst pressure resistance, tube strength, and torque transmission. When radial pressure is applied to the braided tube that is embedded in the construct, the braided tube cannot expand lengthwise. Thus, the compression strength of the construct is increased in the radial direction. This feature takes advantage of the same principle used in the children's toy colloquially known as a Chinese finger trap. The increased radial strength of the tubular construct prevents the construct from collapsing and thereby enhances its structural integrity.Type: ApplicationFiled: May 27, 2022Publication date: December 1, 2022Applicant: Matregenix, Inc.Inventor: Sherif Soliman
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Publication number: 20220161201Abstract: Electrospun poly(acrylic) acid (PAA)/poly(vinyl) alcohol PVA nanofibers and integrated filtration membranes generated therefrom are disclosed herein. The membranes are suitable for use in selectively removing heavy metals such as lead and cadmium from water. The surface of the nanofibers is preferably functionalized with one or more chelating agents. The membranes have a high removal efficiency and adsorption capacity with well-distributed hid-density heavy metal adsorption sites with strong binding affinities for targeted heavy metals.Type: ApplicationFiled: November 22, 2021Publication date: May 26, 2022Applicant: Matregenix, Inc.Inventors: Sherif Soliman, Feng Guo
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Publication number: 20210008505Abstract: The present disclosure describes membranes suitable for use as guided tissue regeneration (GTR) barrier membranes and guided bone regeneration (GBR) barrier membranes in dental applications that are composed of fibrous and highly porous biodegradable materials fabricated using electrospinning and that may be surface-modified with plasma treatment or other suitable methods of surface-modification. The disclosed membranes have a high surface area to volume ratio. The use of the disclosed GTR barrier membranes or GBR barrier membranes provides a barrier that prevents the migration of soft tissue cells but is permeable to small molecules such as nutritional substances and medications. Methods of fabricating the disclosed resorbable barrier dental membranes for GTR and GBR applications using electrospinning are also disclosed. The disclosed membranes may have precisely tuned physical, chemical, and mechanical properties optimized for various GTR and GBR applications.Type: ApplicationFiled: June 23, 2020Publication date: January 14, 2021Applicant: Matregenix, Inc.Inventors: Sherif Soliman, Mohamad Ayad Kamel