Patents Assigned to Matrix Pharmaceutical, Inc./Project Hear
  • Surgical adhesive material
    Patent number: 5290552
    Abstract: The present invention provides a surgical adhesive comprising, in an aqueous composition, fibrinogen, FXIII, collagen, thrombin, Ca.sup.2+ and optionally, an antifibrinolytic agent. The present adhesive may be formed from the patient's plasma without the use of any added reagents for concentration or isolation of the fibrinogen. Conveniently, the adhesive is formulated as a two-part composition which is mixed together just prior to use.
    Type: Grant
    Filed: March 23, 1992
    Date of Patent: March 1, 1994
    Assignee: Matrix Pharmaceutical, Inc./Project Hear
    Inventors: David H. Sierra, Edward E. Luck, Dennis M. Brown