Patents Assigned to Mattioli Engineering Ltd.
  • Patent number: 8647332
    Abstract: A system and method for treating a skin target area includes one or more RF electrodes adapted to provide RF energy for heating the skin target area. A quasi-fractional light unit is adapted to provide optical spots of energy having a wavelength not greater than 1200 nm for heating the skin target area. The RF electrodes and the quasi-fractional light unit are configured to provide energy essentially simultaneously to the skin target area to heat the entire target in non-uniform manner by way of a matrix of spots each having a predetermined diameter.
    Type: Grant
    Filed: October 27, 2009
    Date of Patent: February 11, 2014
    Assignee: Mattioli Engineering Ltd.
    Inventor: Gian Franco Bernabei
  • Patent number: 7945321
    Abstract: A system for enhancing absorption of a substance to be provided on a region of a patient's skin, includes a probe configured to provide the substance to the region of the patient's skin, the probe including a flexible tape with a plurality of cavities, and with an electrically conductive element, such as a conductive wire, provided at one end of each of the cavities. A substance holding material, such as gauze stripes, temporarily holds the substance to be provided on the region of the patient's skin, the substance holding material being provided in each of the cavities. A pulse generator generates a sequence of bursts of electrical pulses to the electrically conductive elements provided within the cavities, so as to provide the bursts of electrical pulses to the region of the patient's skin.
    Type: Grant
    Filed: April 20, 2009
    Date of Patent: May 17, 2011
    Assignee: Mattioli Engineering Ltd.
    Inventor: Gian Franco Bernabei
  • Patent number: 7532926
    Abstract: A removable component for a probe used to treat a patient's skin with a skin-treatment substance, include an attachment device having a plurality of holes for respectively accommodating a plurality of electrodes disposed on a head of the probe. It also includes at least one gauze pad disposed between the attachment device and the head of the probe. The attachment device is removably attached to the head of the probe.
    Type: Grant
    Filed: October 14, 2004
    Date of Patent: May 12, 2009
    Assignee: Mattioli Engineering Ltd.
    Inventor: Gian Franco Bernabei
  • Patent number: 7520875
    Abstract: A system for enhancing absorption of a substance to be provided on a region of a patient's skin, includes a probe configured to provide the substance to the region of the patient's skin, the probe including a flexible tape with a plurality of cavities, and with an electrically conductive element, such as a conductive wire, provided at one end of each of the cavities. A substance holding material, such as gauze stripes, temporarily holds the substance to be provided on the region of the patient's skin, the substance holding material being provided in each of the cavities. A pulse generator generates a sequence of bursts of electrical pulses to the electrically conductive elements provided within the cavities, so as to provide the bursts of electrical pulses to the region of the patient's skin.
    Type: Grant
    Filed: January 25, 2007
    Date of Patent: April 21, 2009
    Assignee: Mattioli Engineering Ltd.
    Inventor: Gian Franco Bernabei
  • Patent number: 7496401
    Abstract: A method and apparatus for transdermal drug delivery to be provided to a patient's skin, includes performing a dermabrasion treatment of the patient's skin so as to lower a skin impedance to below a first value. It also includes providing at least one burst of electrical pulses to the patient's skin that has been dermabrasion treated, wherein each pulses in the at least one burst of electrical pulses is stabilized with respect to a current amount.
    Type: Grant
    Filed: November 19, 2004
    Date of Patent: February 24, 2009
    Assignee: Mattioli Engineering Ltd
    Inventor: Gian Franco Bernabei
  • Patent number: 7471979
    Abstract: A system for enhancing absorption of a substance provided on a region of a patient's skin, includes a probe configured to provide the substance to the region of the patient's skin. The probe includes an array of electrodes provided on a head of the probe. The probe also includes a substance holding unit that temporarily holds the substance to be provided on the region of the patient's skin. The probe further includes a pulse generator that generates a sequence of bursts of electrical pulses to the array of electrodes that are disposed against the region of the patient's skin, so as to provide the bursts of electrical pulses to the region of the patient's skin. The probe also includes a substance applying unit that transfers the substance from the substance holding unit to the head of the probe. The pulse generator provides for pulses to be output in alternate polarities in each of the sequence of bursts.
    Type: Grant
    Filed: November 2, 2005
    Date of Patent: December 30, 2008
    Assignee: Mattioli Engineering Ltd.
    Inventor: Gian Franco Bernabei
  • Patent number: 7376460
    Abstract: A treatment method and apparatus for providing a substance to be absorbed onto a surface of a patient's skin, includes applying the substance onto the surface of the patient's skin by way of a probe head that provides, at the same time: i) bursts of electrical pulses to the skin surface, and ii) vibrations to the skin surface. The vibrations are applied to the skin surface at substantially a same frequency rate, a first harmonic of the same frequency rate, and/or a second harmonic of the same frequency rate, as a burst rate of electrical pulses being applied to the skin surface.
    Type: Grant
    Filed: July 28, 2006
    Date of Patent: May 20, 2008
    Assignee: Mattioli Engineering Ltd.
    Inventor: Gian Franco Bernabei
  • Patent number: 7083580
    Abstract: A treatment method and apparatus for providing a substance to be absorbed onto a surface of a patient's skin, includes applying the substance onto the surface of the patient's skin by way of a probe head that provides, at the same time: i) bursts of electrical pulses to the skin surface, and ii) vibrations to the skin surface. The vibrations are applied to the skin surface at substantially a same frequency rate, a first harmonic of the same frequency rate, and/or a second harmonic of the same frequency rate, as a burst rate of electrical pulses being applied to the skin surface.
    Type: Grant
    Filed: February 24, 2004
    Date of Patent: August 1, 2006
    Assignee: Mattioli Engineering Ltd.
    Inventor: Gian Franco Bernabei
  • Patent number: 7010343
    Abstract: A treatment system and method for enhancing absorption of substances provided on a surface of a patient's skin, includes applying a substance to the surface of the patient's skin by way of a probe that provides at least one of: i) electrical pulses to the skin surface, and ii) vibrational pulses to the skin surface, in order to cause absorption of the substance within the patient's skin. At the same that the substance is applied to the skin, a gauze pad is provided between the probe and the patient's skin. The gauze pad allows for the probe to be moved over the surface of the patient's skin with less friction than if no gauze pad is used, in order to obtain easier movement of the probe with respect to the skin, and to obtain a more even application of the substance to the skin.
    Type: Grant
    Filed: March 27, 2003
    Date of Patent: March 7, 2006
    Assignee: Mattioli Engineering Ltd.
    Inventor: Gian Franco Bernabei
  • Patent number: 6980854
    Abstract: A treatment method for delivery of lidocaine or other type of skin treatment drug to a patient's skin, includes applying electrical bursts of pulses onto the patient's skin by way of electrodes provided on a head of a probe that is placed against the patient's skin. The treatment method also includes applying mechanical vibrations of a same frequency and phase as the bursts of pulses onto the patient's skin by way of a vibrating element provided on the head of the probe. At the same time as the above two steps are being performed, the treatment method includes providing, between the electrodes and the patient's skin, at least two solution-absorbing pads electrically insulated from each other and each one of the two solution-absorbing pads being in electrical contact with one or more of the electrodes on the head of the probe.
    Type: Grant
    Filed: May 30, 2003
    Date of Patent: December 27, 2005
    Assignee: Mattioli Engineering Ltd.
    Inventor: Gian Franco Bernabei
  • Publication number: 20040220622
    Abstract: A treatment method and apparatus for providing a substance to be absorbed onto a surface of a patient's skin, includes applying the substance onto the surface of the patient's skin by way of a probe head that provides, at the same time: i) bursts of electrical pulses to the skin surface, and ii) vibrations to the skin surface. The vibrations are applied to the skin surface at substantially a same frequency rate, a first harmonic of the same frequency rate, and/or a second harmonic of the same frequency rate, as a burst rate of electrical pulses being applied to the skin surface.
    Type: Application
    Filed: February 24, 2004
    Publication date: November 4, 2004
    Applicant: MATTIOLI ENGINEERING LTD.
    Inventor: Gian Franco Bernabei
  • Patent number: 6748266
    Abstract: Application of electrical pulses is made in a controlled manner, in order to increase the absorption of substances applied previously on the skin. Optionally, mechanical vibrations may also be provided to the skin to increase the absorption effect. The electrical pulses are provided to the skin by way of an array of electrodes disposed on a vibrating head plate, and the mechanical vibrations are provided to the skin by way of the vibrating head plate being made to vibrate (if that option is utilized). Preferably, the electrical and mechanical vibrations are at the same frequency and phase with respect to each other, in order to increase the absorption effect.
    Type: Grant
    Filed: July 24, 2002
    Date of Patent: June 8, 2004
    Assignee: Mattioli Engineering Ltd.
    Inventor: Gian Franco Bernabei
  • Patent number: 6743215
    Abstract: Application of electrical pulses and mechanical vibrations to the skin is provided in a controlled manner, in order to increase the absorption of substances applied previously on the skin. A dermabrasion treatment is first performed on a region of the skin to be later given a skin absorption enhancement treatment. After the dermabrasion treatment, electrical pulses are provided to the skin by way of an array of electrodes disposed on a vibrating head, and the mechanical vibrations are provided to the skin by way of the vibrating head being made to vibrate. Preferably, the electrical and mechanical vibrations are at the same frequency and phase with respect to each other, in order to increase the absorption effect. Also, a suction may be applied to the skin, in order to provide for a substantially uniform absorption of the substance that was applied previously on the skin.
    Type: Grant
    Filed: February 14, 2002
    Date of Patent: June 1, 2004
    Assignee: Mattioli Engineering Ltd.
    Inventor: Gian Franco Bernabei
  • Patent number: 6687537
    Abstract: Application of electrical pulses and mechanical vibrations to the skin is provided in a controlled manner, in order to increase the absorption of substances applied previously on the skin. Electrical pulses are provided to the skin by way of an array of electrodes disposed on a vibrating head, and the mechanical vibrations are provided to the skin by way of the vibrating head being made to vibrate. Preferably, the electrical and mechanical vibrations are at the same frequency and phase with respect to each other, in order to increase the absorption effect. Also, a suction is applied to the skin, in order to provide for a substantially uniform absorption of the substance that was applied previously on the skin.
    Type: Grant
    Filed: August 30, 2001
    Date of Patent: February 3, 2004
    Assignee: Mattioli Engineering Ltd.
    Inventor: Gian Franco Bernabei
  • Publication number: 20040015190
    Abstract: A treatment method for delivery of lidocaine or other type of skin treatment drug to a patient's skin, includes applying electrical bursts of pulses onto the patient's skin by way of electrodes provided on a head of a probe that is placed against the patient's skin. The treatment method also includes applying mechanical vibrations of a same frequency and phase as the bursts of pulses onto the patient's skin by way of a vibrating element provided on the head of the probe. At the same time as the above two steps are being performed, the treatment method includes providing, between the electrodes and the patient's skin, at least two solution-absorbing pads electrically insulated from each other and each one of the two solution-absorbing pads being in electrical contact with one or more of the electrodes on the head of the probe.
    Type: Application
    Filed: May 30, 2003
    Publication date: January 22, 2004
    Applicant: MATTIOLI ENGINEERING LTD.
    Inventor: Gian Franco Bernabei
  • Publication number: 20030187478
    Abstract: A treatment system and method for enhancing absorption of substances provided on a surface of a patient's skin, includes applying a substance to the surface of the patient's skin by way of a probe that provides at least one of: i) electrical pulses to the skin surface, and ii) vibrational pulses to the skin surface, in order to cause absorption of the substance within the patient's skin. At the same that the substance is applied to the skin, a gauze pad is provided between the probe and the patient's skin. The gauze pad allows for the probe to be moved over the surface of the patient's skin with less friction than if no gauze pad is used, in order to obtain easier movement of the probe with respect to the skin, and to obtain a more even application of the substance to the skin.
    Type: Application
    Filed: March 27, 2003
    Publication date: October 2, 2003
    Applicant: MATTIOLI ENGINEERING LTD.
    Inventor: Gian Franco Bernabei
  • Patent number: 6587730
    Abstract: Radio frequency current pulses are applied to the skin in a controlled manner in order to heat selected volumes of skin, thereby inducing the removal of unwanted pigments from the skin and also enhancement of collagen formation on the skin. A probe provides the radio frequency current pulses to the skin, where the probe includes first and second metallic stripes, and where the probe is connected to two coaxial cables that are respectively connected to the first and second metallic stripes. The two coaxial cables are connected to a balanced/unbalanced transformer, which in turn is connected to a radio frequency generator that provides radio frequency pulses.
    Type: Grant
    Filed: April 2, 2001
    Date of Patent: July 1, 2003
    Assignee: Mattioli Engineering Ltd.
    Inventor: Gian Franco Bernabei
  • Patent number: 6535761
    Abstract: Application of electrical pulses and mechanical vibrations to the skin is provided in a controlled manner, in order to increase the absorption of substances applied previously on the skin. Electrical pulses are provided to the skin by way of an array of electrodes disposed on a vibrating head, and the mechanical vibrations are provided to the skin by way of the vibrating head being made to vibrate. Preferably, the electrical and mechanical vibrations are at the same frequency and phase with respect to each other, in order to increase the absorption effect.
    Type: Grant
    Filed: August 7, 2001
    Date of Patent: March 18, 2003
    Assignee: Mattioli Engineering Ltd.
    Inventor: Gian Franco Bernabei
  • Patent number: 6518538
    Abstract: A radio frequency generated plasma is provided to a skin surface in a controlled manner, in order to heat and selectively damage a thin superficial layer, thereby inducing a renewal process of the epidermis. The plasma is generated by providing a vacuum to the probe, and also providing an rf pulse to an electrode within the probe, thereby creating a glow discharge that includes gas ions that contact the skin and cause the skin to heat up.
    Type: Grant
    Filed: October 12, 2001
    Date of Patent: February 11, 2003
    Assignee: Mattioli Engineering Ltd.
    Inventor: Gian Franco Bernabei
  • Patent number: 6514262
    Abstract: A dermabrasion apparatus operating by a flow of air and reducing substances conveyed by a pneumatic system through a handpiece. The apparatus comprises a housing, a vacuum pump, and an external tray inside of which a mixing bottle and a collecting bottle are provided. The apparatus further comprises at least one external source of pressurized sterilized air, or other suitable gas. The handpiece and the bottles are disposable sterilized components. Two or more of the components can be color-coded and sold in a kit.
    Type: Grant
    Filed: July 12, 2000
    Date of Patent: February 4, 2003
    Assignee: Mattioli Engineering Ltd.
    Inventors: Dario Di Fiore, Carlo Stanisci