Patents Assigned to Max-Delbrueck-Centrum fur Molekulare Medizin Berlin-Buch
  • Polynucleotides for medical use
    Patent number: 9115404
    Abstract: The invention pertains to a RNA molecule transcribed form a long terminal repeat (LTR) sequence, comprising a sequence encoding a gene, such as CSF1R, and a sequence that is at least in part found in the LTR, in particular for detecting cancer in a subject.
    Type: Grant
    Filed: June 21, 2010
    Date of Patent: August 25, 2015
    Assignee: MAX-DELBRÜCK-CENTRUM FÜR MOLEKULARE MEDIZIN BERLIN-BUCH
    Inventors: Stephan Mathas, Björn Lamprecht, Bernd Dörken, Constanze Bonifer
  • Polynucleotides for use in medicine
    Patent number: 9040238
    Abstract: The invention refers to polynucleotides selected from the group consisting of a) polynucleotides encoding for the polypeptide RBM20 comprising a P638L mutation for a human polypeptide RBM20, or a P641L mutation for a rat polypeptide RBM20, b) polynucleotides with a reverse complementary sequence of the polynucleotide of a) above, and c) polynucleotides with an identity at least 50% to a polynucleotide of a) or b) above.
    Type: Grant
    Filed: June 22, 2010
    Date of Patent: May 26, 2015
    Assignee: MAX-DELBRÜCK-CENTRUM FÜR MOLEKULARE MEDIZIN BERLIN-BUCH
    Inventors: Michael Gotthardt, Norbert Hübner, Marion Lewis Greaser, Wei Guo
  • HIGH AFFINITY T CELL RECEPTOR AND USE THEREOF
    Publication number: 20140348805
    Abstract: The present invention is directed to a high affinity T cell receptor (TCR) against a tumor-associated antigen, an isolated nucleic acid molecule encoding same, a T cell expressing said TCR, and a pharmaceutical composition for use in the treatment of diseases involving malignant cells expressing said tumor-associated antigen.
    Type: Application
    Filed: March 25, 2014
    Publication date: November 27, 2014
    Applicant: Max-Delbrueck-Centrum fur Molekulare Medizin Berlin-Buch
    Inventors: Dolores Jean Schendel, Susanne Wilde, Bernhard Frankenberger, Wolfgang Uckert