Patents Assigned to MAX INTERNATIONAL, LLC
  • Methods for reducing oxidative stress in a cell with a sulfhydryl protected glutathione prodrug
    Patent number: 9173917
    Abstract: The present invention relates to compositions and methods for reducing oxidative stress in a cell, increasing glutathione levels in a cell, increasing L-cysteine levels in a cell and reducing hepatocytotoxicity by contacting a cell with a sulfhydryl protected glutathione prodrug or a sulfhydryl protected cysteine prodrug.
    Type: Grant
    Filed: July 12, 2012
    Date of Patent: November 3, 2015
    Assignees: Max International, LLC, The United States of America as represented by the Department of Veteran Affairs
    Inventors: Herbert T. Nagasawa, Jonathan F. Cohen
  • Method to enhance delivery of glutathione and ATP levels in cells
    Patent number: 9144570
    Abstract: A therapeutic method is provided comprising treating a mammal subject to hypoxia with an amount of 2(R,S)-D-ribo-(1?,2?,3?,4?-tetrahydroxybutyl)thiazolidine-4(R)-carboxylic acid (RibCys) or a pharmaceutically acceptable salt thereof effective to both maintain, restore or increase both the ATP levels and the glutathione (GSH) levels in said tissue.
    Type: Grant
    Filed: August 2, 2013
    Date of Patent: September 29, 2015
    Assignee: Max International, LLC
    Inventor: Herbert T. Nagasawa
  • COMPOSITIONS COMPRISING SUGAR-CYSTEINE PRODUCTS
    Publication number: 20140348811
    Abstract: The present invention provides compositions comprising sugar, cysteine, and/or sugar-cysteine products, methods of preparing the same, and/or using the same.
    Type: Application
    Filed: July 27, 2012
    Publication date: November 27, 2014
    Applicant: MAX INTERNATIONAL, LLC
    Inventors: Herbert T. Nagasawa, David Bagley, Scott Momii, Scott Nagasawa
  • Compositions comprising sugar-cysteine products
    Patent number: 8853170
    Abstract: The present invention provides compositions comprising sugar, cysteine, and/or sugar-cysteine products.
    Type: Grant
    Filed: January 28, 2011
    Date of Patent: October 7, 2014
    Assignee: Max International, LLC
    Inventors: David Bagley, Scott Momii, Scott Nagasawa, Herbert T. Nagasawa
  • Method To Enhance Delivery Of Glutathione And ATP Levels In Cells
    Publication number: 20130317072
    Abstract: A therapeutic method is provided comprising treating a mammal subject to hypoxia with an amount of 2(R,S)-D-ribo-(1?,2?,3?,4?-tetrahydroxybutyl)thiazolidine-4(R)-carboxylic acid (RibCys) or a pharmaceutically acceptable salt thereof effective to both maintain, restore or increase both the ATP levels and the glutathione (GSH) levels in said tissue.
    Type: Application
    Filed: August 2, 2013
    Publication date: November 28, 2013
    Applicant: Max International LLC
    Inventor: Herbert T. Nagasawa
  • Method to enhance delivery of glutathione and ATP levels in cells
    Patent number: 8501700
    Abstract: A therapeutic method is provided comprising treating a mammal subject to hypoxia with an amount of 2(R,S)-D-ribo-(1?,2?,3?,4?-tetrahydroxybutyl)thiazolidine-4(R)-carboxylic acid (RibCys) or a pharmaceutically acceptable salt thereof effective to both maintain, restore or increase both the ATP levels and the glutathione (GSH) levels in said tissue.
    Type: Grant
    Filed: July 30, 2008
    Date of Patent: August 6, 2013
    Assignee: Max International LLC
    Inventor: Herbert T. Nagasawa
  • METHODS FOR REDUCING OXIDATIVE STRESS IN A CELL WITH A SULFHYDRYL PROTECTED GLUTATHIONE PRODRUG
    Publication number: 20120295855
    Abstract: The present invention relates to compositions and methods for reducing oxidative stress in a cell, increasing glutathione levels in a cell, increasing L-cysteine levels in a cell and reducing hepatocytotoxicity by contacting a cell with a sulfhydryl protected glutathione prodrug or a sulfhydryl protected cysteine prodrug.
    Type: Application
    Filed: July 12, 2012
    Publication date: November 22, 2012
    Applicants: Department of Veterans Affairs, Max International, LLC
    Inventors: Herbert T. Nagasawa, Jonathan F. Cohen
  • Compositions And Beverages Comprising Nutrients, Vitamins, Sugars, Cysteine, And/Or Sugar-Cysteine Products
    Publication number: 20110287109
    Abstract: The present invention provides compositions comprising vitamins, minerals, nutrients, sugar, cysteine, and/or sugar-cysteine products, methods of preparing the same, and/or using the same.
    Type: Application
    Filed: May 23, 2011
    Publication date: November 24, 2011
    Applicant: MAX INTERNATIONAL, LLC
    Inventors: David Bagley, Scott Momii, Scott Nagasawa, Herbert T. Nagasawa
  • Methods Of Preparing Thiazolidines
    Publication number: 20110184185
    Abstract: The present invention provides methods of preparing thiazolidines, and in particular methods of preparing ribose-cysteine.
    Type: Application
    Filed: January 28, 2011
    Publication date: July 28, 2011
    Applicant: MAX INTERNATIONAL, LLC
    Inventors: Herbert T. Nagasawa, Kurt Wachholder
  • Compositions Comprising Sugar-Cysteine Products
    Publication number: 20110183927
    Abstract: The present invention provides compositions comprising sugar, cysteine, and/or sugar-cysteine products, methods of preparing the same, and/or using the same.
    Type: Application
    Filed: January 28, 2011
    Publication date: July 28, 2011
    Applicant: MAX INTERNATIONAL, LLC
    Inventors: David Bagley, Scott Momii, Scott Nagasawa, Herbert T. Nagasawa