Patents Assigned to Max-Planck-Gesellschaft zur Forderung
  • Publication number: 20250041609
    Abstract: An apparatus for determining an arrhythmia of a living heart comprises a signal evaluation device receiving a signal representing a present electric activity of the heart, and determining a frequency spectrum of the signal. The apparatus further comprises a pulse generator generating a sequence of electric pulses to be applied to the heart at a pulse repetition frequency that depends on the frequency spectrum and decreases by at least 20% over the sequence.
    Type: Application
    Filed: October 25, 2024
    Publication date: February 6, 2025
    Applicant: Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V.
    Inventors: Stefan Luther, Ulrich Parlitz, Thomas Lilienkamp
  • Publication number: 20250035536
    Abstract: In order to map the surface of a macromolecule, at least one fluorescent probe is introduced into a medium in which the macromolecule is embedded or will be embedded. Then, a plurality of spatial positions of the at least one fluorescent probe with regard to the macromolecule are determined via localization of the at least one singularized fluorescent probe with a simple standard deviation of no more than 2 nm. For this purpose, fluorescence light photons emitted by the singularized fluorescent probe are recorded. In addition, a bounding surface bounding the determined spatial positions with regard to the macromolecule is determined; and a three-dimensional map of at least a part of the surface of the macromolecule is generated from the bounding surface.
    Type: Application
    Filed: October 11, 2024
    Publication date: January 30, 2025
    Applicant: Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V.
    Inventor: Stefan W. Hell
  • Publication number: 20250040443
    Abstract: According to a method of manufacturing a magnetic memory device, various types of magnetic memory devices can be manufactured at low cost by manufacturing a plurality of magnetic modules by using a delamination phenomenon of pattern segments and stacking the plurality of magnetic modules to complete a stacked memory device.
    Type: Application
    Filed: July 18, 2024
    Publication date: January 30, 2025
    Applicants: Samsung Electronics Co., Ltd., Max-Planck-Gesellschaft zur Forderung der Wissenschaften e.V.
    Inventors: Unghwan Pi, Stuart Papworth Parkin, Jaechun Jeon, Jaekeun Kim, Andrea Migliorini
  • Patent number: 12209260
    Abstract: The present invention relates to a fusion protein, comprising the structure N-PCSY-degSigN-M-PCSX-degSigC-C; wherein N represents the N-terminus; PCSY and PCSX each represent a protease cleavage site (PCS), which differ from each other in at least one amino acid residue: degSigN represents a degradation signal which promotes degradation of the fusion protein in a host cell if PCSY is cleaved by a protease such that the first amino acid of degSigN becomes the new N-terminus of the remaining fusion; M represents a cytoplasmic selection marker; and degSigC represents a second degradation signal which promotes degradation of the fusion protein in a host cell if PCSX is not cleaved by a protease; and C represents the C-terminus.
    Type: Grant
    Filed: June 13, 2019
    Date of Patent: January 28, 2025
    Assignee: MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V.
    Inventors: Arturo Vera Rodriguez, Dirk Görlich, Steffen Frey
  • Publication number: 20250029644
    Abstract: A magnetic memory device includes a lower magnetic track layer extending in a first direction and including a plurality of first magnetic domains, a spacer layer on the lower magnetic track layer and extending in the first direction, an upper magnetic track layer on the spacer layer and extending in the first direction, the upper magnetic track layer including a plurality of second magnetic domains, and a plurality of read units on the upper magnetic track layer and arranged apart from one another in the first direction, wherein the plurality of first magnetic domains and the plurality of second magnetic domains have magnetization directions parallel to each other at positions overlapping each other in a second direction perpendicular to the first direction.
    Type: Application
    Filed: July 16, 2024
    Publication date: January 23, 2025
    Applicant: Max-Planck-Gesellschaft zur Forderung der Wissenschaften e.V.
    Inventors: Unghwan Pi, Stuart Papworth Parkin, Jaechun Jeon, Jaekeun Kim, Andrea Migliorini
  • Publication number: 20250029670
    Abstract: A method of operating a magnetic memory device includes: (i) applying a first current to a free layer of a magnetic tunnel junction structure, which includes a magnetic translation unit (MTU) extending between a first magnetic pad and a second magnetic pad, and a tunnel barrier layer and a pinned layer stacked on the MTU, so that a multi-domain is established within the MTU, (ii) applying a magnetic field to the free layer so that the magnetization direction of the MTU switches to become anti-parallel to the magnetization directions of the first magnetic pad and the second magnetic pad, (iii) applying a second current to the free layer so that a portion of the multi-domain penetrates into the first magnetic pad, and (iv) applying another magnetic field to the free layer so that the magnetization direction of the first magnetic pad switches.
    Type: Application
    Filed: July 16, 2024
    Publication date: January 23, 2025
    Applicants: Samsung Electronics Co., Ltd., Max-Planck-Gesellschaft zur Forderung der Wissenschaften e.V.
    Inventors: Unghwan Pi, Stuart Papworth Parkin, Andrea Migliorini, Jaechun Jeon
  • Patent number: 12205967
    Abstract: An avalanche photodiode array for detecting electromagnetic radiation comprises: a semiconductor substrate (100) having a first main surface (101) and a second main surface (102), which are opposite one another, a plurality of n-doped anode regions (1) formed at the first main surface (101) and separated from one another by pixel isolation regions (7), a p-doped cathode region (3) arranged at the second main surface (102) opposite the anode regions, a drift region (4) between the plurality of anode regions (1) and the cathode region (3), and a p-doped multiplication layer (2) arranged below the plurality of anode regions (1) and below the pixel isolation regions (7), and is characterized by an n-doped field reduction layer (9) arranged below the plurality of anode regions (1) and the pixel isolation regions (7) and above the multiplication layer (2).
    Type: Grant
    Filed: March 30, 2020
    Date of Patent: January 21, 2025
    Assignee: Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V.
    Inventors: Rainer Richter, Florian Schopper, Jelena Ninkovic, Alexander Bähr
  • Patent number: 12205042
    Abstract: In one aspect the application relates to a computing system for providing data for modelling a human brain comprises a database including a plurality of datasets (or allow access to a plurality of datasets), each dataset including at least a dynamical model of the brain including at least one node and a neurodataset of a neuroimaging modality input. The at least one node include a representation of a local dynamic model and a parameter set of the local dynamic model.
    Type: Grant
    Filed: January 23, 2023
    Date of Patent: January 21, 2025
    Assignees: Max-Planck-Gesellschaft Zur Förderung Der Wissenschaften e.V., Baycrest Centre for Geriatric Care, Universite D'Aix Marseille, Centre National De La Recherche Scientifique, Institut National De La Sante Et De La Recherche Medicale, Codebox Computerdienste GmbH
    Inventors: Anthony Randal McIntosh, Jochen Mersmann, Viktor Jirsa, Petra Ritter
  • Publication number: 20250019422
    Abstract: The present invention pertains in the fields of antibody technology, protein engineering, medicine, pharmacology, infection biology, virology, and medical diagnostics. More specifically, the present disclosure provides VHH antibodies that prevent cell entry of and infection by SARS-CoV-2 and that have been selected for potent cross-reaction and cross-neutralization between the original Wuhan strain and the Alpha, Beta, Gamma, Delta, and Mu variants of concern.
    Type: Application
    Filed: November 22, 2022
    Publication date: January 16, 2025
    Applicant: MAX-PLANCK-GESELLSCHAFT ZUR FÖRDERUNG DER WISSENSCHAFTEN E.V.
    Inventors: Dirk GÖRLICH, Metin AKSU, Oleh RYMARENKO, Thomas GÜTTLER, Renate REES, Kathrin GREGOR, Waltraud TAXER, Jürgen SCHÜNEMANN, Matthias DOBBELSTEIN, Kim Maren STEGMANN, Antje DICKMANNS
  • Patent number: 12184030
    Abstract: A broadband light source device for creating broadband light pulses includes a hollow-core fiber and a pump laser source device. The hollow-core fiber is configured to create the broadband light pulses by an optical non-linear broadening of pump laser pulses. The hollow-core fiber includes a filling gas, an axial hollow light guiding fiber core configured to support core modes of a guided light field, and an inner fiber structure surrounding the fiber core and configured to support transverse wall modes of the guided light field. The pump laser source device is configured to create and provide the pump laser pulses at an input side of the hollow-core fiber. The transverse wall modes include a fundamental transverse wall mode and second and higher order transverse wall modes.
    Type: Grant
    Filed: April 12, 2023
    Date of Patent: December 31, 2024
    Assignee: MAX-PLANCK-GESELLSCHAFT ZUR FÖRDERUNG DER WISSENSCHAFTEN E. V.
    Inventors: Patrick Sebastian Uebel, Philip St. J. Russell, Sebastian Thomas Bauerschmidt
  • Patent number: 12173042
    Abstract: The current disclosure relates to methods for treating ovarian cancer based on specific antigen expression of the cancer. Furthermore, the expressed antigen may be used in immunotherapeutic methods for treatment of the ovarian cancer. Aspects of the disclosure relate to immunotherapies targeting CT45 polypeptides, methods for treating ovarian cancer based on CT45 expression, and kits for detecting CT45 polypeptides and nucleotides.
    Type: Grant
    Filed: January 28, 2022
    Date of Patent: December 24, 2024
    Assignees: Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E. V.
    Inventors: Ernst Lengyel, Matthias Mann, Marion Curtis, Fabian Coscia
  • Patent number: 12173309
    Abstract: The present invention relates to compounds, compositions and kits suitable to precise genome editing efficiency in a eukaryotic target cell or target organism.
    Type: Grant
    Filed: April 10, 2018
    Date of Patent: December 24, 2024
    Assignee: Max-Planck-Gesellschaft zur Forderung der Wissenschaften e.V.
    Inventors: Stephan Riesenberg, Tomislav Maricic
  • Patent number: 12165683
    Abstract: A magnetic memory device includes a conductive line that extends in a first direction, and a magnetic track line that extends in the first direction on a top surface of the conductive line. The conductive line may include a first region having a first width in a second direction, and a second region having a second width in the second direction. The first direction and the second direction are parallel to the top surface of the conductive line and are perpendicular to each other. The second width may be greater than the first width. The magnetic track line includes first domains arranged in the first direction on the first region of the conductive line, and second domains arranged in the first direction on the second region of the conductive line. A size of each of the second domains may be less than a size of each of the first domains.
    Type: Grant
    Filed: January 12, 2023
    Date of Patent: December 10, 2024
    Assignees: Samsung Electronics Co., Ltd., Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V.
    Inventors: Stuart Papworth Parkin, Jaechun Jeon, Andrea Migliorini, Ung Hwan Pi
  • Publication number: 20240407177
    Abstract: The present invention relates to racetrack memory array devices, and more specifically, to a manufacturing method of racetrack memory arrays with integrated magnetic tunnel junction for read/write.
    Type: Application
    Filed: September 14, 2022
    Publication date: December 5, 2024
    Applicant: MAX PLANCK GESELLSCHAFT ZUR FÖRDERUNG DER WISSENSCHAFTEN EV
    Inventors: Stuart S.P. PARKIN, See-Hun YANG, Ungh-wan PI, Jaewoo JEONG
  • Publication number: 20240381847
    Abstract: The present disclosure relates to an electronic tag for behavioural monitoring of animals, the electronic tag comprising a microprocessor and at least one sensor. The electronic tag is configured to obtain, via the at least one sensor, movement data of an animal to which the electronic tag is attached and to determine, based on the obtained movement data, a behaviour of the animal. The disclosure further encompasses a corresponding method as well as an ear tag.
    Type: Application
    Filed: May 16, 2024
    Publication date: November 21, 2024
    Applicants: MAX-PLANCK-GESELLSCHAFT ZUR FÖRDERUNG DER WISSENSCHAFTEN E.V., SOUTH AFRICAN NATIONAL PARKS, GEPE GEIMUPLAST GMBH
    Inventors: Georg HEINE, Bernd VORNEWEG, Martin Christoph WIKELSKI, Ursula Rosa MÜLLER, Jens KOBLITZ, Ockert Louis VAN SCHALKWYK, Pauli VILJOEN, Johann SCHÖPF, Josef HUTSTEINER, Timm WILD
  • Patent number: 12145951
    Abstract: The present invention relates to inorganic-organic hybrid compounds for use in medicine or for use as medication, consisting of an inorganic metal cation and an organic platinum-containing cytostatic anion, in particular also a cisplatin derivative.
    Type: Grant
    Filed: July 26, 2019
    Date of Patent: November 19, 2024
    Assignees: Karlsruher Institut fur Technologie, Max-Planck-Gesellschaft zur Forderung der Wissenschaften e.V.
    Inventors: Beatrice Lilli Neumeier, Claus Feldmann, Joanna Napp, Frauke Alves
  • Patent number: 12145386
    Abstract: A method for preparing a laser marking system to create a colored laser mark on a specimen by providing a laser marking system and a specimen comprising a surface layer, where the laser marking system has a preset number of laser parameters, and performing an exploration of a first gamut specified by the laser marking system and the specimen. The method further generally comprises creating a design space with a preset number of design points; performing a marking of a sample on the specimen for each design point; measuring the sample using at least one detection device and determining a performance point for each design point; evaluating the performance space with regard to preset performance criteria using an evaluation device; generating an offspring design space with offspring design points; and creating a first gamut using a subset of performance points.
    Type: Grant
    Filed: June 21, 2021
    Date of Patent: November 19, 2024
    Assignees: Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V, Università della Svizzera italiana (USI)
    Inventors: Hans-Peter Seidel, Vahid Babaei, Sebastian Cucerca, Piotr Didyk
  • Publication number: 20240366800
    Abstract: The present invention relates to improved methods for obtaining purified contrast agents that are suitable for magnetic resonance imaging. The contrast agents are prepared by a method such dynamic nuclear polarization (DNP), hydrogenative parahydrogen induced polarization (PHIP), or Signal Amplification By Reversible Exchange (SABRE). High degrees of purity are achieved by performing an evaporation step to separate a signal enhanced precursor or the contrast agent from a metal catalyst or a source of radicals.
    Type: Application
    Filed: August 26, 2022
    Publication date: November 7, 2024
    Applicant: MAX-PLANCK-GESELLSCHAFT ZUR FÖRDERUNG DER WISSENSCHAFTEN E. V.
    Inventors: Stefan GLÖGGLER, Sergey KORCHAK
  • Publication number: 20240371424
    Abstract: A method for switching magnetic moments in a magnetic material by: a) heating a system formed from a layer of magnetic material and a layer of a metal contacting and forming an interface with one surface of the magnetic material layer, the heating step increasing the temperature to at least 1 to 100 K above the blocking temperature of the magnetic material, b) applying current pulses having a fall time to the system at least at a point in time when the system is heated to at least 1 to 100 K above the blocking temperature of the magnetic material, thereby generating a spin texture in the magnetic material layer and c) then cooling the system to a temperature of below the blocking temperature at a cooling rate which is greater than the current pulses fall time, thereby setting the spin texture in the magnetic layer.
    Type: Application
    Filed: June 15, 2022
    Publication date: November 7, 2024
    Applicant: MAX PLANCK GESELLSCHAFT ZUR FÖRDERUNG DER WISSENSCHAFTEN EV
    Inventors: Stuart S.P. PARKIN, Banabir PAL, Binoy KRISHNA HAZRA, See-Hun YANG
  • Patent number: 12135405
    Abstract: An optical component comprising a planar metasurface arranged on a surface of a first substrate and a top layer arranged in a height direction Z above the metasurface, wherein the metasurface comprises a plurality of scattering structures, wherein a dielectric material is deposited on a subset of the plurality of scattering structures, wherein an active media is sandwiched between the metasurface and the top layer, wherein an incident electromagnetic radiation is transmitted or reflected by the optical component, wherein a phase profile modulation is induced on the incident electromagnetic radiation during the reflection or transmission.
    Type: Grant
    Filed: November 13, 2020
    Date of Patent: November 5, 2024
    Assignee: Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V.
    Inventors: Laura Na Liu, Jianxiong Li