Patents Assigned to Max-Planck Gesellschaft zur Forderung der Wissenschaften, C.V.
  • Catalysis of the cis/trans-isomerisation of secondary amide peptide compounds
    Patent number: 7589065
    Abstract: The present invention is based on the finding that the cis/trans isomerisation of secondary amide peptide bonds in oligo- and polypeptides can be catalytically promoted. This catalysis is effected by enzymes which are hereinafter called “secondary amide peptide bond cis/trans isomerases (APIases). It can be assumed that the APIase activity plays a central role in a number of pathophysiological processes. Thus, the invention relates to pharmaceutical compositions comprising substances which inhibit APIase activity.
    Type: Grant
    Filed: August 20, 2002
    Date of Patent: September 15, 2009
    Assignee: Max-Planck Gesellschaft zur Forderung der Wissenschaften, C.V.
    Inventors: Cordelia Schiene-Fischer, Gunter Fischer, Judith Maria Habazettl, Gerhard Küllertz
  • Process for producing proteins using gram negative host cells
    Patent number: 5268270
    Abstract: For the gene-technological production of proteins, a vector is introduced to gram-negative host cells which contains at least one gene coding translated. For the extracellular obtaining of the proteins its coding gene is so inserted into a vector which contains the IgA-protease precursor gene from micro-organisms of the genus Neisseria that the coding gene is positioned within the sequence of the IgA-protease precursor gene. A plasmid especially suitable for this purpose is the plasmid pIP100 contained in E. coli DSM 3775.
    Type: Grant
    Filed: February 29, 1988
    Date of Patent: December 7, 1993
    Assignee: Max-Planck-Gesellschaft zur Forderung der Wissenschaften c.V.
    Inventors: Thomas F. Meyer, Roman Halter, Johannes Pohlner