Abstract: The present invention relates to methods, compositions and kits for determining the prognosis of a clinical response in a human patient to a medicament which acts in the central nervous system and which is a substrate of the ABCB1 protein. Further, the invention relates to a combination of medicaments for the treatment of human patients having specific polymorphisms in the ABCB1 gene.
Type:
Application
Filed:
May 12, 2005
Publication date:
March 13, 2008
Applicant:
Max-Planck-Gesellschft Zur Foerderung Der Wissenschaften e.V.
Inventors:
Manfred Uhr, Florian Holsboer, Elisabeth Binder, Bertram Mueller-Myhsok