Patents Assigned to Max Planck Institute
  • Publication number: 20220237905
    Abstract: A method and system for training a model for image generation. The model includes a hybrid variational auto-encoder (VAE)—generative adversarial network (GAN) framework. The method includes the steps of: multiple input of an input image into the VAE which outputs in response multiple distinct output image samples, determining the best of the multiple output image samples as a best-of-many sample, the best-of-many sample having the minimum reconstruction cost, and training the model based on a predefined training objective, the predefined training objective integrating the best-of-many sample reconstruction cost and a GAN-based synthetic likelihood term.
    Type: Application
    Filed: May 28, 2019
    Publication date: July 28, 2022
    Applicants: TOYOTA MOTOR EUROPE, MAX-PLANCK-INSTITUT FÜR INFORMATIK
    Inventors: Daniel OLMEDA REINO, Apratim BHATTACHARYYA, Mario FRITZ, Bernt SCHIELE
  • Patent number: 10851130
    Abstract: The present disclosure discloses the chemical synthesis method of the Plesiomonas shigelloides serotype O51 O-antigen oligosaccharide, belonging to the field of chemistry. Source-abundant D-glucose, L-fucose, D-glucosamine and the like are used as raw materials to prepare three glycosylation building blocks, the synthetic route composed of 11 reaction modules is designed, and through the optimization of protecting group and the optimization of the time of introducing functional group, the preparation of the target oligosaccharide chain is successfully achieved. The oligosaccharide chain prepared in the present disclosure has the advantages of cheap and easy-to-get raw materials, and simple and easy-to-repeat preparation method. The present disclosure will have good application prospects in the aspects of development of new drugs and vaccines of Plesiomonas shigelloides, and the like.
    Type: Grant
    Filed: December 10, 2018
    Date of Patent: December 1, 2020
    Assignees: Jiangnan University, Max Planck Institute of Colloids and Interfaces
    Inventors: Jian Yin, Jing Hu, Peter Seeberger, Chunjun Qin
  • Patent number: 10544481
    Abstract: The invention relates to a method for the recovery of precious metal from materials containing precious metal, said method comprises the following steps of: A) bringing the materials containing the precious metal into contact with an oxidizing agent, B) bringing the material containing the precious metal into contact with a reducing agent. Said method offers the possibility of recovering precious metal in a simple manner and in high purity from secondary materials.
    Type: Grant
    Filed: October 25, 2016
    Date of Patent: January 28, 2020
    Assignee: Max-Planck-Institut für Eisenforschung GmbH
    Inventors: Nejc Hodnik, Claudio Baldizzone, Karl Mayrhofer
  • Patent number: 10512605
    Abstract: The present disclosure discloses an integrated nano system for liver-targeting co-delivery of genes/drugs and a preparation method, belonging to the field of biomedicines. In the disclosure, a plurality of functions are integrated in a carrier having good biocompatibility and safety, a nucleic acid/drug-loading copolymer portion having a pH-stimulating response function is formed by poly(N,N-dimethylaminoethyl methacrylate) (PDMAEMA) grafted with poly(3-azido-2-hydroxypropylmethacrylate) (PGMA-N3), and a fluorescence-based imaging component Rhodamine B (RhB) and galactose are used as targeting ligands. The drug delivery system provided by the present disclosure is safe, is capable of taking a synergistic effect of gene/drug therapy, and is expected to play a great role in clinical application.
    Type: Grant
    Filed: December 10, 2018
    Date of Patent: December 24, 2019
    Assignees: Jiangnan University, Max Planck Institute of Colloids and Interfaces
    Inventors: Jian Yin, Jing Hu, Peter Seeberger, Zhou Ye
  • Publication number: 20190032161
    Abstract: The invention provides a reliably manufacturable flat steel product based on a Fe3Al alloy and a method that allows the production of such flat steel products. For this purpose, the flat steel product is made of a steel which comprises (in % by weight) Al: 12-20%, Ti: 0.2-2%, B: 0.1-0.6%, in each case at least one element from the group “Cr, C, Mn, Si, Nb, Ta, W, Zr, V, Mo, Ni, Cu, Ca, rare earth metals, and Co” unavoidable impurities. The method according to the invention specifies that a molten steel with the stated composition is cast as a precursor in the form of a slab, thin slab or a cast strip, the precursor is then hot rolled into a hot strip.
    Type: Application
    Filed: January 20, 2016
    Publication date: January 31, 2019
    Applicants: ThyssenKrupp Steel Europe AG, thyssenkrupp AG, Max-Planck-Institut für Eisenforschung GmbH
    Inventors: Harald HOFMANN, Hans FERKEL, Michael GÖVERT, Matthias SCHIRMER, Martin PALM, Dirk PONGE, Andreas LEITNER
  • Patent number: 9915614
    Abstract: Methods, systems, and devices are disclosed for molecular capture, manipulation, and analysis. In one aspect, a device to aggregate and characterize particles in a fluid includes an electrically insulative substrate including a channel to carry an electrically conducting fluid containing particles, electrodes located in the channel forming a nanoscale opening and including an insulating layer over their surface at the opening, a first circuit to apply a non-uniform ac electric field and a dc bias signal across the electrodes, in which the applied non-uniform ac electric field produces a positive dielectrophoretic force to aggregate the particles in a trapping region including the opening and adjacent region, a second circuit to detect changes in a dc current caused by at least some of the particles in the trapping region, and an optical device that directs a coherent light beam on the opening to determine Raman spectra of the particles in the trapping region.
    Type: Grant
    Filed: April 26, 2013
    Date of Patent: March 13, 2018
    Assignees: ACADEMIA SINICA, MAX-PLANCK-INSTITUT FUR EISENFORSCHUNG GMBH
    Inventors: Chia-Fu Chou, Lesser-Rojas Leonardo, Ming-Lee Chu, Andreas Erbe
  • Publication number: 20180064712
    Abstract: The present invention encompasses methods of reducing inflammatory immune cell activation and inflammation via inhibiting mitochondrial fission.
    Type: Application
    Filed: June 8, 2017
    Publication date: March 8, 2018
    Applicant: Max Planck Institute
    Inventors: Erika L. Pearce, Michael D. Buck, David O'Sullivan, Francesc Baixauli
  • Publication number: 20140320849
    Abstract: Methods, systems, and devices are disclosed for molecular capture, manipulation, and analysis. In one aspect, a device to aggregate and characterize particles in a fluid includes an electrically insulative substrate including a channel to carry an electrically conducting fluid containing particles, electrodes located in the channel forming a nanoscale opening and including an insulating layer over their surface at the opening, a first circuit to apply a non-uniform ac electric field and a dc bias signal across the electrodes, in which the applied non-uniform ac electric field produces a positive dielectrophoretic force to aggregate the particles in a trapping region including the opening and adjacent region, a second circuit to detect changes in a dc current caused by at least some of the particles in the trapping region, and an optical device that directs a coherent light beam on the opening to determine Raman spectra of the particles in the trapping region.
    Type: Application
    Filed: April 26, 2013
    Publication date: October 30, 2014
    Applicants: MAX-PLANCK-INSTITUT FÜR EISENFORSCHUNG GMBH, ACADEMIA SINICA
    Inventors: Chia-Fu Chou, Lesser-Rojas Leonardo, Ming-Li Chu, Andreas Erbe
  • Publication number: 20130338744
    Abstract: Graphene, can be used to make an implantable neuronal prosthetic which can be indefinitely implanted in vivo. Graphene electrodes are placed on a 3C—SiC shank and electrical insulation is provided by conformal insulating SiC. These materials are not only chemically resilient, physically durable, and have excellent electrical properties, but have demonstrated a very high degree of biocompatibility. Graphene also has a large specific capacitance in electrolytic solutions as well as a large surface area which reduces the chances for irreversible Faradaic reactions. Graphene can easily be constructed on SiC by the evaporation of Si from the surface of that material allowing for mechanically robust epitaxial graphene layers that can be fashioned into electrodes using standard lithography and etching methods.
    Type: Application
    Filed: May 30, 2013
    Publication date: December 19, 2013
    Applicants: Max-Planck-Institute for Solid State Research, University of South Florida
    Inventors: Christopher Leroy Frewin, Stephen E. Saddow, Camilla Coletti
  • Publication number: 20120000580
    Abstract: A corrosion-resistant austenitic steel is claimed which, in each case relative to 100 mass percent, contains 20 to 32% manganese, 10 to 15% chromium, a total of 0.5 to 1.3% carbon and nitrogen, wherein the ratio of carbon to nitrogen is 0.5 to 1.5, the remainder being iron and melt-related impurities. The claimed steel can be produced and processed at normal pressure and has TWIP properties. It is in particular suited for producing structural components in constructs, such as in the automotive industry.
    Type: Application
    Filed: March 3, 2010
    Publication date: January 5, 2012
    Applicant: MAX-PLANCK-INSTITUT FUER EISENFORSCHUNG GMBH
    Inventors: Sebastian Weber, Lais Mujica Roncery
  • Patent number: 7806165
    Abstract: In a method for making hot strips, a workable lightweight construction steel is used which in particular can easily be deep-drawn cold and includes the main elements Si, Al and Mn, with high tensile strength and good TRIP and/or TWIP characteristics. The mass % are as follows for C 0.04 to <1.0, Al 0.05 to <4.0, SI 0.05 to ?6.0; Mn 9.0 to ?30.0, the remainder being iron with the common incidental steel elements. The melt is cast in a horizontal strip casting unit, close to the final dimensions at calm flow and without bending to form a pre-strip in the range between 6 and 15 mm, and subsequently is fed for further processing.
    Type: Grant
    Filed: December 22, 2004
    Date of Patent: October 5, 2010
    Assignees: Salzgitter Flachstahl GmbH, Max-Planck-Institut Für Eisenforschung GmbH
    Inventors: Joachim Kroos, Karl-Heinz Spitzer, Georg Frommeyer, Volker Flaxa, Udo Brüx, Klaus Brockmeier
  • Publication number: 20100064384
    Abstract: The invention relates to a method of modifying the ATP-ADP ratio in a cell, tissue, organ, microorganism or plant by altering the hemoprotein activity in the cell, and to the use of the method.
    Type: Application
    Filed: March 20, 2007
    Publication date: March 11, 2010
    Applicant: Max Planck Institut fur molekulare
    Inventor: Thorsten Zank
  • Publication number: 20100037350
    Abstract: This invention relates generally to plant cells and/or plants with increased yield as compared to a corresponding non-transformed wild type plant cell by increasing or generating one or more activities of polypeptides associated with the intermediate phosphoribosylpyrophosphate (PRPP) in plants. In particular, this invention relates to plant cells and/or plants with increased yield as compared to a corresponding non-transformed wild type plant cell by increasing or generating one or more activities of phosphoribosyl pyrophosphate synthases (PRPP synthetase, PRS) The invention also deals with methods of producing and screening for and breeding such plant cells and/or plants.
    Type: Application
    Filed: October 12, 2007
    Publication date: February 11, 2010
    Applicants: BASF Plant Science GmbH, Max-Planck-Institut fuer Molekulare Pflanzenphysiologie
    Inventors: Thorsten Zank, Oliver Oswald, Jörg Bauer, Rita Maria Zrenner, Silke Koslowsky
  • Publication number: 20090251765
    Abstract: The present invention relates to a composition for photon energy up-conversion, a system comprising said composition and to uses of said composition and said system.
    Type: Application
    Filed: April 8, 2008
    Publication date: October 8, 2009
    Applicants: Max-Planck-Institut fur Polymerforschung, Sony Deutschland GmbH
    Inventors: Tzenka MITEVA, Gabriele Nelles, Akio Yasuda, Stanislav Balouchev, John Lupton, Panagiotis Keivanidis
  • Patent number: 7411396
    Abstract: An MRI apparatus is presented that includes a computer programmed to sample a single volume element (voxel) for MR spectroscopy and automatically determine respective metabolite concentrations for multiple compartment contained in the single voxel. The invention is effective in assigning metabolite concentrations to specific tissue types on a per-voxel basis for a VOI. Moreover, the invention is effective in providing metabolite concentrations for a voxel independent of that voxel's vicinity relative to the coils of the phased array. The present invention provides an effective tool in assigning metabolite concentrations from mixed pathological and normal tissues.
    Type: Grant
    Filed: May 8, 2006
    Date of Patent: August 12, 2008
    Assignees: General Electric Company, Max-Planck-Institut fur Psychiatrie
    Inventors: Timo Schirmer, Michael Czisch
  • Publication number: 20050137132
    Abstract: The present invention is directed to kappaM (?M) conopeptide RIIIK and its use for blocking the flow of potassium ions through voltage-gated potassium channels. The ?M conopeptides include unglycosylated and O-glycosylated peptides.
    Type: Application
    Filed: July 16, 2004
    Publication date: June 23, 2005
    Applicants: University of Utah Research Foundation, Max Planck Institut for Experimental Medicine
    Inventors: Baldomero Olivera, Maren Watkins, Heinrich Terlau, Michael Ferber
  • Patent number: 6842704
    Abstract: A tumor necrosis factor-? converting enzyme (TACE) is produced, purified, and crystallized. The three-dimensional coordinates of the crystal are obtained by X-ray diffraction. The coordinates can be recorded on a computer readable medium, or are part of a video memory, where they can be used as part of a system for studying for studying TACE. The coordinates are also used in designing, screening, and developing compounds that associate with TACE.
    Type: Grant
    Filed: February 4, 1999
    Date of Patent: January 11, 2005
    Assignees: Immunex Corporation, Max-Planck-Institute for Biochemistry, Wyeth
    Inventors: Roy A. Black, Raymond James Paxton, Wolfram Bode, Klaus Maskos, Carlos Fernandez-Catalan, James Ming Chen, Jeremy Ian Levin
  • Patent number: 6663989
    Abstract: A structure containing a ferroelectric material comprises a substrate such as silicon, a buffer layer formed on the substrate, and a non-c-axis-oriented, electrically-conductive template layer formed on the buffer layer. The template layer comprises a perovskite oxide compound. An epitaxially a-axis-oriented ferroelectric layer is formed on the template layer, and has a vector of spontaneous polarization oriented perpendicular or at least substantially perpendicular to the film normal.
    Type: Grant
    Filed: March 28, 2002
    Date of Patent: December 16, 2003
    Assignee: Max-Planck-Institut fur Mikrostrukturphysik
    Inventors: Ho Nyung Lee, Stephan Senz, Alina Visinoiu, Alain Pignolet, Dietrich Hesse, Ulrich Gösele
  • Patent number: 6531235
    Abstract: A structure containing a ferroelectric material comprises a substrate comprising silicon, a buffer layer formed on the substrate, and a non-c-axis-oriented, electrically-conductive template layer formed on the buffer layer. The template layer comprises a perovskite oxide compound. A non-c-axis-oriented, anisotropic perovskite ferroelectric layer is formed on the template layer.
    Type: Grant
    Filed: June 6, 2001
    Date of Patent: March 11, 2003
    Assignee: Max-Planck-Institute für Mikrostrukturphysik
    Inventors: Ho Nyung Lee, Stephan Senz, Alina Visinoiu, Alain Pignolet, Dietrich Hesse, Ulrich Gösele
  • Patent number: 6218468
    Abstract: In a process for the preparation of an aqueous polymer dispersion by the free radical aqueous emulsion polymerization method, the polymerization is carried out in the presence of frozen micelles of amphiphilic substances.
    Type: Grant
    Filed: July 22, 1998
    Date of Patent: April 17, 2001
    Assignees: BASF Aktiengesellschaft, Max-Planck-Institut
    Inventors: Klemens Mathauer, Walter Mächtle, Wolfgang Schrof, Horst Schuch, Timo Rager, Wolfgang Meyer, Gerhard Wegner