Abstract: The invention relates to polynucleotides and polypeptides as defined in the claims for use in the treatment of a disorder associated with abnormal telomerase activity and/or abnormal telomere length in comparison to healthy subjects in a subject. Moreover, the present invention provides a method of identifying an agent capable of decreasing telomerase activity and/or telomere length, and a method of classifying a cancer as a telomerase-negative cancer, as defined in the claims.
Type:
Application
Filed:
September 14, 2011
Publication date:
November 14, 2013
Applicant:
Max-Planok-Gesellschaft Zur Forderung Der Wissenschaften E.V.
Inventors:
Dennis Kappei, Frank Buchholz, Matthias Mann, Falk Butter