Abstract: Disclosed is a method for producing flavor-active terpenes from terpene hydrocarbons. According to said method, a lyophilized mycel which is first rehydrated and is then mixed with the substrate is used preferably in a submerged culture in the framework of selective biotransformation with the aid of microorganisms. The inventive method, which can be carried out especially in an enantioselective, stereoselective, and/or regioselective manner, makes it possible to obtain terpenoid alcohols, epoxides, aldehydes, ketones, polyalcohols, carbonyls, and carbonyl alcohols with the aid of fusarium, pleutorus, penicillium, and chaetomium species, the obtained substances being isolated particularly from cellular components. Said method should be carried out above all in a stirred tank, surface reactor, or fixed bed reactor while preferably taking place in a two-phase system with reduced carbon source moieties.
Type:
Grant
Filed:
February 10, 2005
Date of Patent:
September 28, 2010
Assignee:
Maxens GmbH
Inventors:
Martin Müller, Kerstin Dirlam, Hans Henning Wenk, Ralf G. Berger, Ulrich Krings, Rüdiger Kaspera