Abstract: A container may include a storage volume configured to store a payload. A thermal insulation layer may surround the storage volume. A thermoregulation layer may surround the thermal insulation layer. There may be activation of a chemical reaction in the thermoregulation layer. The thermal insulation layer may have R-value per inch configured to expose the payload to a desired temperature to ensure viability of the payload and dampen a temperature spike of the chemical reaction. A system of containers may include a system storage volume with N containers in the system storage volume, wherein N is a whole number of 2 or more. A method of making an insulated container may include preparing an outer skin barrier layer, stacking a thermoregulation layer on the outer skin barrier layer, stacking a thermal insulation layer on the thermoregulation layer, and stacking an inner skin barrier layer on the thermal insulation layer.

Abstract: A container may include a storage volume configured to store a payload. A thermal insulation layer may surround the storage volume. A thermoregulation layer may surround the thermal insulation layer. There may be activation of a chemical reaction in the thermoregulation layer. The thermal insulation layer may have R-value per inch configured to expose the payload to a desired temperature to ensure viability of the payload and dampen a temperature spike of the chemical reaction. A system of containers may include a system storage volume with N containers in the system storage volume, wherein N is a whole number of 2 or more. A method of making an insulated container may include preparing an outer skin barrier layer, stacking a thermoregulation layer on the outer skin barrier layer, stacking a thermal insulation layer on the thermoregulation layer, and stacking an inner skin barrier layer on the thermal insulation layer.

Abstract: Status of a payload and a shipping container is tracked and monitored by a tracking module which receives at least one signal from one or more sensors; determines a rate of change over time for the signal(s) and sensor(s); compares, in real-time, memory-stored rate-of-change thresholds corresponding to a payload type to the determined rate(s) of change; and, responsive to the comparison indicating a current or impending violation of a payload handling condition, powers up a wireless communications interface, communicates a digital report to a remote computing system, and powers down the wireless communications interface upon completion of the communicating of the report, while continuing to monitor the sensor(s).

Abstract: Status of a payload and a shipping container is tracked and monitored by a tracking module which receives at least one signal from one or more sensors; determines a rate of change over time for the signal(s) and sensor(s); compares, in real-time, memory-stored rate-of-change thresholds corresponding to a payload type to the determined rate(s) of change; and, responsive to the comparison indicating a current or impending violation of a payload handling condition, powers up a wireless communications interface, communicates a digital report to a remote computing system, and powers down the wireless communications interface upon completion of the communicating of the report, while continuing to monitor the sensor(s).

Abstract: A storage and shipping container system for a set of specific related components, such as multiple blood products, which conveys the components in pre-determined ratios, having a thermally-insulated main container with a plurality of internal chambers, and at least one attached auxiliary container which is thermally-insulated. Optionally, the system is provided with wheels and a collapsible handle for easy movement of one system, and configured for stacking of multiple similar systems for bulk transportation.

Abstract: A shipping and storage system which has an access panel with an optional open/close status sensor, and a payload carrier with an affixed sensor connected to a tracking module that monitors the environment of the payload carrier, such as temperature, against a pre-determined threshold for compliance with pre-determined handling and storage requirements for a specific payload type, such as a specific blood product. When a violation is detected by the tracking module, a user alert or user interface is activated. Advanced features optionally include a plurality of pre-determined threshold sets for a plurality of specific payload types, a tamper detection function based on the access panel status and optional weight changes in the payload carrier, and wireless connectivity to allow mobile device and cloud-based enhanced management functions.