Patents Assigned to MAYNE PHARMA LLC
  • Patent number: 12589100
    Abstract: The present invention provides a composition and method for treating various skin diseases. The composition is formulated as a foamable composition and includes the corticosteroid halobetasol.
    Type: Grant
    Filed: August 19, 2019
    Date of Patent: March 31, 2026
    Assignee: MAYNE PHARMA LLC
    Inventors: Robert T. Gauthier, James D. Hammer, Wayne S. Alden, IV
  • Publication number: 20260076913
    Abstract: The present application is directed to stabilized core-shell microcapsules comprising a core of benzoyl peroxide (BPO) or all trans retinoic acid (ATRA) and a metal-oxide shell; and to pharmaceutical compositions and methods of use thereof.
    Type: Application
    Filed: November 24, 2025
    Publication date: March 19, 2026
    Applicant: Mayne Pharma LLC
    Inventors: Ofer TOLEDANO, Karine NEIMANN, Danil FINKEL-MOISEEV, Maya ERLICH, Dorit MARCO
  • Patent number: 12491163
    Abstract: The present application is directed to stabilized core-shell microcapsules comprising a core of benzoyl peroxide (BPO) or all trans retinoic acid (ATRA) and a metal-oxide shell; and to pharmaceutical compositions and methods of use thereof.
    Type: Grant
    Filed: May 23, 2021
    Date of Patent: December 9, 2025
    Assignee: Mayne Pharma LLC
    Inventors: Ofer Toledano, Karine Neimann, Danil Finkel-Moiseev, Maya Erlich, Dorit Marco
  • Publication number: 20250339394
    Abstract: The present application is directed to compositions comprising microcapsules comprising encapsulated tretinoin, wherein the microcapsule size is less than 50 ?m; and to methods of use thereof.
    Type: Application
    Filed: July 14, 2025
    Publication date: November 6, 2025
    Applicant: Mayne Pharma LLC
    Inventors: Ofer TOLEDANO, Karine Neimann, Maya Erlich, Dorit Marco
  • Patent number: 12357602
    Abstract: The present application is directed to compositions comprising microcapsules comprising encapsulated tretinoin, wherein the microcapsule size is less than 50 ?m; and to methods of use thereof.
    Type: Grant
    Filed: July 12, 2018
    Date of Patent: July 15, 2025
    Assignee: Mayne Pharma LLC
    Inventors: Ofer Toledano, Karine Neimann, Maya Erlich, Dorit Marco
  • Patent number: 12350255
    Abstract: The present invention provides stabilized cream formulations of oxymetazoline and uses thereof. The present invention also provides a method of treating facial erythema associated with rosacea in a patient in need of such treatment, comprising topically administering once or twice daily to the site of erythema on the face of the patient a pharmaceutical composition comprising 0.5%, 1.0% or 1.5% oxymetazoline or a pharmaceutically acceptable salt thereof as the sole active ingredient.
    Type: Grant
    Filed: December 1, 2022
    Date of Patent: July 8, 2025
    Assignee: Mayne Pharma LLC
    Inventors: Pramod Sarpotdar, Kevin Warner, Steven Zhang, Gurpreet Ahluwalia, Amy Kuang
  • Patent number: 12350382
    Abstract: The invention relates to a process for coating a solid, water-insoluble particulate matter, with a metal oxide comprising: (a) contacting the solid, water-insoluble particulate matter with an ionic additive and an aqueous medium to obtain a dispersion of said particulate matter having positive charges on its surface; (b) subjecting the particulate matter to a coating procedure comprising precipitating a metal oxide salt onto the surface of the particulate matter to form a metal oxide layer thereon to thereby obtain particulate matter coated by a metal oxide coating layer; (c) repeating step (b) at least 4 more times; and (d) aging said coating layer. The invention further relates to particles comprising a particulate matter coated by a metal oxide layer, to a use of the particles for topical administration, and to a method for preventing, reducing, or eliminating pests at a locus, using the particles.
    Type: Grant
    Filed: February 3, 2008
    Date of Patent: July 8, 2025
    Assignee: Mayne Pharma LLC
    Inventors: Ofer Toledano, Haim Bar-Simantov, Nissim Bilman, Leora Shapiro, Raed Abu-Reziq, Srikanth Sriadibhatla, William T. Sommer, Hanan Sertchook
  • Patent number: 11020407
    Abstract: The present invention provides a method for treating various skin diseases by topically administering to a subject a composition formulated as a foamable composition which includes a corticosteroid, such as halobetasol. The composition may include a corticosteroid, ethyl alcohol, emulsifying wax, cetostearyl alcohol, polyoxyl 20 cetostearyl ether, water, benzoic acid and propellant.
    Type: Grant
    Filed: November 30, 2016
    Date of Patent: June 1, 2021
    Assignee: MAYNE PHARMA LLC
    Inventors: Robert T. Gauthier, James D. Hammer
  • Patent number: 10857159
    Abstract: The present invention provides a composition and method for treating various skin diseases. The composition is formulated as a foamable composition and includes the corticosteroid halobetasol.
    Type: Grant
    Filed: November 30, 2016
    Date of Patent: December 8, 2020
    Assignee: MAYNE PHARMA LLC
    Inventors: Robert T. Gauthier, James D. Hammer
  • Patent number: 10688071
    Abstract: The present invention relates to a novel oil in water emulsion aerosol foam composition containing an active agent for the treatment of various chronic and acute skin conditions, particularly acne and psoriasis; and processes for preparing the emulsion aerosol foam compositions. In particular, the present invention relates to oil in water emulsion aerosol foam compositions containing a retinoid in the oil phase.
    Type: Grant
    Filed: July 19, 2012
    Date of Patent: June 23, 2020
    Assignee: MAYNE PHARMA LLC
    Inventor: Leon Loupenok
  • Patent number: 10568859
    Abstract: The present invention relates to a novel oil in water emulsion aerosol foam composition containing an active agent for the treatment of various chronic and acute skin conditions, particularly acne and psoriasis; and processes for preparing the emulsion aerosol foam compositions. In particular, the present invention relates to oil in water emulsion aerosol foam compositions containing a retinoid in the oil phase.
    Type: Grant
    Filed: February 24, 2010
    Date of Patent: February 25, 2020
    Assignee: MAYNE PHARMA LLC
    Inventor: Leon Loupenok