Abstract: A method for three-dimensional parallel magnetic resonance imaging (MRI) using an MRI system is provided. The method includes determining in-plane acceleration factors that optimize a selected criterion, such as an image quality criterion defined by maximal noise amplification in a reconstructed image. The estimated in-plane acceleration factors are used to establish a k-space sampling pattern, which is used to acquire k-space data. An image is reconstructed from the acquired k-space data using a parallel image reconstruction technique.

Abstract: Methods for performing rapid and accurate thermocycling on a sample are disclosed. Use of non-contact heating and cooling sources allows precise temperature control with sharp transitions from one temperature to another to be achieved. A wide range of temperatures can be accomplished according to these methods. In addition, thermocycling can be performed without substantial temperature gradients occurring in the sample. Apparatus for achieving these methods are also disclosed. A method for pumping a sample through microchannels on a microchip using a non-contact heat source is also disclosed.