Patents Assigned to MBM & Co.
  • Immunological compositions and methods of use to transiently alter mammalian central nervous system myelin to promote neuronal regeneration
    Patent number: 6969516
    Abstract: A method is described comprising the combined administration of a novel composition comprising serum complement proteins with complement-fixing antibodies to induce transient disruption of myelin and/or demyelination. The antibodies specifically bind to one or more epitopes of myelin, and complement proteins. A method is also described for promoting regrowth, repair, and regeneration of neurons in a mammalian subject. The methods can be used following immediate or chronic injury.
    Type: Grant
    Filed: October 28, 1998
    Date of Patent: November 29, 2005
    Assignee: MBM & Co.
    Inventors: John D. Steeves, Jason K. Dyer, Hans S. Keirstead