Abstract: The disclosure relates to a compound of formula (I): wherein X, A, Y and X1 are as defined in the description. The disclosure also relates to a conjugate between a protein comprising at least two disulfide bridges and a compound of formula (I).
Type:
Grant
Filed:
July 19, 2021
Date of Patent:
September 8, 2026
Assignee:
MC SAF
Inventors:
Ludovic Juen, Camille Gely, Estelle Huet
Abstract: Disclosed are novel antibody-drug conjugates and use thereof in therapy, in particular in anticancer or anti-inflammatory therapy, as well as synthetic products useful as linkers, composed of a linker head and a linker body, and also a method for preparing the linkers and the antibody-drug conjugates.
Type:
Grant
Filed:
April 11, 2019
Date of Patent:
March 22, 2022
Assignee:
MC SAF
Inventors:
Nicolas Joubert, Marie Claude Viaud-Massuard, Renaud Respaud
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