Patents Assigned to McGill Univ.
  • Patent number: 7056532
    Abstract: A composition for facilitating delivery of biological agents, comprising a supramolecular complex including as constituents a block copolymer, having at least one nonionic, water soluble segment and at least one polyionic segment, and at least one charged surfactant having hydrophobic groups, the charge of the surfactant being opposite to that of the polyionic segment of the block copolymer. The constituents of the complex are bound by interaction between the opposite charges thereof and between surfactant hydrophobic groups. The complex may include an anionic surfactant having a biological activity, in which case the net charge of such anionic surfactant is no more than about 10.
    Type: Grant
    Filed: June 11, 1998
    Date of Patent: June 6, 2006
    Assignees: Univ. Nebraska Bd. of Regents, Moscow State Univ., McGill Univ.
    Inventors: Alexander V. Kabanov, Adi Eisenberg, Victor A. Kabanov
  • Patent number: 5100645
    Abstract: In accordance with the present invention, there is now provided a method for the diagnosis of amyloidosis, which comprises subjecting a protein sample such as serum, cerebrospinal fluid or brain tissues containing amyloid deposits obtained from a patient suspected of suffering from an amyloidosis related disease to measurement of the amount of ubiquitin in said sample, and comparing the resulting amount with the amount of ubiquitin in a normal healthy patient. In a second aspect of the present invention, there is provided a method for the diagnosis of Alzheimer's disease, which comprises subjecting a protein sample obtained from the brain extract or cerebrospinal fluid of a patient suspected of suffering from Alzheimer's disease to measurement of the amount of ubiquitin, and comparing the resulting amount with the amount of ubiquitin in a normal healthy patient.
    Type: Grant
    Filed: October 19, 1990
    Date of Patent: March 31, 1992
    Assignee: Royal Institution for the Advancement of Learning (McGill Univ.)
    Inventors: Zafer Ali-Khan, Kamel Alizadeh-Khiavi
  • Patent number: 5028253
    Abstract: There is disclosed a process for controlling undesirable vegetation, espelly velvetleaf by applying Colletotrichum coccodes spores onto the undesirable vegetation or onto the situs of the undesirable vegetation. The composition including the fungus spores in an agricultural carrier as well as the growing of the fungus on solid or liquid media are also disclosed. The spores germinate, infect the undesirable vegetation and result in a pathogenic disease which kills or reduces the growth of this undesirable plant.
    Type: Grant
    Filed: July 20, 1988
    Date of Patent: July 2, 1991
    Assignees: The Royal Institution for the Advancement of Learning (McGill Univ.), The Univ. of Vermont and State Agriculturual College
    Inventors: Alan K. Watson, Alan R. Gotlieb
  • Patent number: 4804460
    Abstract: In the froth flotation of ore in a column, the froth/pulp interface level and the efficiency of the froth washing operation are controlled by determining a profile of temperatures measured in the froth layer and slurry below the interface. Temperatures are measured with temperature sensing elements immersed in the froth layer and extending to below the interface level. The measured profile is compared with a target profile and deviations are corrected by changing the tailings flowrate or the washwater flowrate to return a measured profile to the target profile. An inflection point in the profile occurs at the interface level. The inflection point in a measured profile is compared with a level set point, and a deviation from set point value is corrected by increasing or decreasing the flow of tailings whereby the interface level returns to its set point.
    Type: Grant
    Filed: March 1, 1988
    Date of Patent: February 14, 1989
    Assignee: Royal Inst. for Advancement of Learn., A.K.A. (McGill Univ.)
    Inventors: Michael H. Moys, James A. Finch
  • Patent number: 4593073
    Abstract: The invention is concerned with a novel polymer addition product comprising hydrophilic polymer backbone having a molecular weight of at least about 5,000 and to which are attached amino acid containing pendants, the pendants containing at least one arginine or lysine amino acid. The polymeric compounds of the invention are highly efficient adsorbents for bilirubin and other bile pigments, as well as for bile acids such as cholic acid.
    Type: Grant
    Filed: April 23, 1985
    Date of Patent: June 3, 1986
    Assignee: The Royal Institution for the Advancement of Learing (McGill Univ.)
    Inventors: Leon E. St-Pierre, G. Ronald Brown, Dominique S. Henning, Marlene Bouvier