Abstract: The present application relates to combination treatments for bacterial infections. For example, the application relates to the use of one or more ?-lactam antibiotics and one or more compounds of Formula I: (I) for treatment of a metallo-B-lactamase-expressing bacterial infection or a disease, disorder or condition arising from a metallo-B-lactamase-expressing bacterial infection.
Type:
Application
Filed:
May 7, 2014
Publication date:
March 24, 2016
Applicant:
Mcmaster Uuniversity
Inventors:
Gerry Wright, Wenliang Wang, Andrew King