Abstract: A tire curing press for curing vulcanized tires includes an upper cavity part and a base that at least partially forms the lower cavity part. A movable platen is supported by the base that supports a tire mold section received within the upper cavity part. In various examples, an outer riser column is secured to the base and extends vertically upwards from the base to support the upper cavity part, a multi-height lock ring is disposed upon the base and is configured to interface with an annular flange of the upper cavity part via a bayonet connection, first and second cylinders are configured to apply a substantially equal squeeze pressure to the movable platen to thereby establish a final tire curing pressure within the press cavity, and/or a lock plate is carried by the upper cavity part and includes a locking surface for selective engagement with an abutment shoulder.

Abstract: A segmented mold operator includes a main frame fixed to an upper cavity part of a tire press cavity and a control plunger with an axially movable cylinder rod that is configured to apply a squeeze pressure to the tire press cavity. A rotatable lock ring is rotatably coupled about an end of the cylinder rod and axially movable therewith. The lock ring includes a plurality of teeth radially arranged thereon to interface with a mold ring adapter via a bayonet connection. A lock ring frame is independent from the rotatable lock ring and is separated therefrom along the cylinder rod. A locking plunger is configured to selectively engage the rotatable lock ring to thereby prevent rotation of the rotatable lock ring. An electronic lock sensor is configured to electronically sense an axial position of the lock rod.

Abstract: Solid pharmaceutical dosage form for the release of at least one Active Pharmaceutical Ingredient (API) in the oral cavity comprising a core coated by at least one film coating. The core comprises at least one API. One or more organoleptically disturbing sensations induced by one or several of the APIs and/or of inactive components of the solid pharmaceutical dosage form is/are reduced by constituents of said film coating. Said constituents comprise at least one film-forming polymer and at least one flavoring agent or at least one sweetener.

Abstract: A liquid composition comprising racecadotril and cyclodextrin.

Abstract: The invention relates to a tablet capable of being chewed or disintegrated in the oral cavity, which comprises an enteric coated aspirin active ingredient, and preferably a lightly compressed matrix comprising directly compressible carbohydrate(s) and at least one sweetener.

Abstract: The present invention features the present invention features a machine for the production of a solid dosage form including: (a) a die platen having one or more forming cavities each having an inner wall, a first opening at the surface of one side of the die platen, and a second opening at the surface on the opposite side of the die platen; (b) one or more first forming tools each adapted to move into one of the forming cavities through the first opening of the forming cavity; (c) one or more second forming tools each adapted to move adjacent to one of the second openings or into one of the forming cavities through the second opening of the forming cavity; (d) at least one first RF electrode operably associated with the one or more first forming tools, the one or more second forming tools, or the inner wall of the one or more forming cavities; and (e) at least one second RF electrode operably associated with the one or more first forming tools.

Abstract: The present invention features a tablet including one or more pharmaceutically active agent(s), one or more thickeners, and one or more binder(s), wherein the tablet includes at least 200 mg of the pharmaceutically active agent(s) and the tablet has been fused with the binder(s) such that the tablet (i) has a water permeation time of less than 60 seconds and (ii) has an in vitro disintegration time of greater than 60 seconds.

Abstract: A liquid composition comprising racecadotril and cyclodextrin.

Abstract: The invention relates generally to mouth rinses for the prevention and elimination of bad breath as well as for the reduction of oral microorganisms responsible for the development of dental plaque and tooth decay. In particular, the present invention relates to a non-alcohol or reduced alcohol mouth rinses effective at preventing the above-mentioned problems.

Abstract: The present invention relates to oral compositions, comprising select polyethylene oxide-polypropylene oxide block copolymer surfactants. Methods for using the compositions are also disclosed.

Abstract: A composition comprising: a benefit agent; at least one polymer including a polycaprolactone polymer; at least one lower alcohol; and at least one co-solvent; and a method for enhancing topical delivery of a benefit agent is disclosed.

Abstract: A tooth sensitivity treatment composition is disclosed. The composition includes a compound of Formula I M1-A-M2-B-M3??(I) wherein: M1 and M3 are, independently, a monovalent or divalent metal; M2 is a polyvalent metal or metal oxide; and A and B are, independently, selected from the group consisting of C2-C6 diacids, triacids, and tetraacids. Methods for treating tooth sensitivity are also disclosed.

Abstract: A fluid management device for use in a mammalian body has at least one fluid transport element capable of interfacing with a mammalian body element to provide a substantially uninterrupted fluid conduit. The fluid conduit provides a fluid path between at least one fluid transport element and the storage element. A distal portion of the at least one fluid transport element is capable of extending away from the fluid storage element, and the at least one fluid transport element has a Wing Stiffness of less than about 10 gf.

Abstract: The invention provides a composition containing hyaluronic acid (HA) or a pharmaceutically-acceptable salt thereof preserved with a cationic preservative and related methods. In one embodiment, the pharmaceutically-acceptable salt is sodium hyaluronate.

Abstract: A fluid management device for use in a mammalian body has at least one fluid transport element capable of interfacing with a mammalian body element to provide a substantially uninterrupted fluid conduit. The fluid conduit provides a fluid path between at least one fluid transport element and the storage element. A distal portion of the at least one fluid transport element is capable of extending away from the fluid storage element, and the at least one fluid transport element has a Wing Stiffness of less than about 10 gf.

Abstract: A fluid management device for use in a mammalian body has at least one fluid transport element capable of interfacing with a mammalian body element to provide a substantially uninterrupted fluid conduit. The fluid conduit provides a fluid path between at least one fluid transport element and the storage element. A distal portion of the at least one fluid transport element is capable of extending away from the fluid storage element, and the at least one fluid transport element has a Wing Stiffness of less than about 10 gf.

Abstract: A device for directing a liquid onto a plurality of surfaces of the oral cavity, the device including a handle, a neck, and a head, where the head includes a cleaning component including a chamber for maintaining the liquid proximate the surfaces, where the chamber is defined by front and rear sealing membranes, inner side walls and a base inner wall, and where the inner side walls each include a plurality of openings, the device further including a first manifold and a second manifold, and a first port and a second port for conveying liquid.

Abstract: A device for directing a liquid onto a plurality of surfaces of the oral cavity, the device including a handle, a neck, and a head, where the head includes a cleaning component including a chamber for maintaining the liquid proximate the surfaces, where the chamber is defined by front and rear sealing membranes, inner side walls and a base inner wall, and where the inner side walls each include a plurality of openings, the device further including a first manifold and a second manifold, and a first port and a second port for conveying liquid.