Abstract: A tamper-resistant vessel which contains a liquid is provided with a non-adherent multi-walled construction having, in one embodiment, at least two adjacent non-adherent layers for providing a void in between to enable tamper indication by discoloration indicative of gross spoilage. In one embodiment, the container or vessel has an opaque inner wall and a closely spaced transparent outer wall, with a void in between. Puncture from the outside through the two walls provides seepage of the interiorly-carried liquid between the multiple walls to provide the look of spoilage.
Type:
Grant
Filed:
May 20, 1987
Date of Patent:
March 28, 1989
Assignee:
McNeilab Inc.
Inventors:
E. Joseph Stillwell, George E. Pickering, Richard E. Merrill
Abstract: A tamper-resistant vessel which contains a liquid is provided with a non-adherent multi-walled construction having, in one embodiment, at least two adjacent non-adherent layers for providing a void in between to enable tamper indication by discoloration indicative of gross spoliage. In one embodiment, the container or vessel has an opaque inner wall and a closely spaced transparent outer wall, with a void in between. Puncture from the outside through the two walls provides seepage of the interiorly-carried liquid between the multiple walls to provide the look of spoilage.
Type:
Grant
Filed:
May 20, 1987
Date of Patent:
July 5, 1988
Assignee:
McNeilab Inc.
Inventors:
Arthur A. Massucco, E. Joseph Stilwell, George E. Pickering, Richard E. Merrill
Abstract: N-aryl-N'-(2-thiazolidinylidene)urea compounds of Formula II ##STR1## wherein: R is CH.sub.3, C.sub.2 H.sub.5, or H;R.sub.1 is CH.sub.3, C.sub.2 H.sub.5, Cl, Br, F, CF.sub.3, OCH.sub.3 or H, provided that R.sub.1 is not H where R is H;R.sub.2 is CH.sub.3 or H, provided that R.sub.2 is not H when R is H;R.sub.3 is H or F or CH.sub.3 ;R.sub.4 is H or CH.sub.3 ;R.sub.5 is CH.sub.3, C.sub.2 H.sub.5, Cl, Br, F, CF.sub.3, OCH.sub.3, have anticonvulsant activity and are useful in the treatment of epilepsy.
Abstract: Glycidic acid derivatives substituted in the 2-position with a long chain dibromoalkyl of from 11 to 16 carbons having hypoglycemic activity.
Type:
Grant
Filed:
April 20, 1978
Date of Patent:
January 2, 1979
Assignee:
McNeilab Inc.
Inventors:
Richard J. Mohrbacher, Winston Ho, Gene F. Tutwiler