Patents Assigned to MDNA Life Sciences Inc.
  • Mitochondrial mutations and rearrangements as a diagnostic tool for the detection of sun exposure, prostate cancer and other cancers
    Patent number: 10907213
    Abstract: Mitochondrial DNA deletions useful for the detection of cancers and sun exposure are provided. In particular, methods and kits for detecting mitochondrial DNA deletions for the early detection, diagnosis and progression of prostate cancer, sun exposure and non-melonoma skin cancer are provided.
    Type: Grant
    Filed: August 29, 2017
    Date of Patent: February 2, 2021
    Assignee: MDNA Life Sciences Inc.
    Inventors: Ryan L. Parr, Robert Thayer, Gabriel Dakubo, Jennifer Creed, Kerry Robinson, Andrea Maggrah, Brian Reguly, Andrew Harbottle, Mark Birch-Machin
  • 3.4 kb mitochondrial DNA deletion for use in the detection of cancer
    Patent number: 10308987
    Abstract: A method for detecting cancer in an individual comprising detecting a deletion in the nucleic acid sequence between residues 10743 and 14125 in mitochondrial DNA, obtaining a biological sample from the individual, extracting the mitochondrial DNA (mtDNA) from the sample, quantifying the amount of mtDNA in the sample having a deletion in the nucleic acid sequence between residues 10743 and 14125 of the mtDNA genome, and comparing the amount of mtDNA in the sample having the deletion to at least one known reference sample.
    Type: Grant
    Filed: March 27, 2017
    Date of Patent: June 4, 2019
    Assignee: MDNA Life Sciences Inc.
    Inventors: Ryan L. Parr, Robert Thayer, Gabriel D. Dakubo, Jennifer Creed, Kerry Robinson, Andrea Maggrah, Brian Reguly
  • Aberrant mitochondrial DNA, associated fusion transcripts and hybridization probes therefor
    Patent number: 10266899
    Abstract: The present invention provides novel mitochondrial fusion transcripts and the parent mutated mtDNA molecules that are useful for predicting, diagnosing and/or monitoring cancer. Hybridization probes complementary thereto for use in the methods of the invention are also provided.
    Type: Grant
    Filed: February 20, 2015
    Date of Patent: April 23, 2019
    Assignee: MDNA Life Sciences Inc.
    Inventors: Ryan Parr, Brian Reguly, Gabriel Dakubo, Jennifer Creed, Kerry Robinson
  • Mitochondrial mutations and rearrangements as a diagnostic tool for the detection of sun exposure, prostate cancer and other cancers
    Patent number: 9745632
    Abstract: Mitochondrial DNA deletions useful for the detection of cancers and sun exposure are provided. In particular, methods and kits for detecting mitochondrial DNA deletions for the early detection, diagnosis and progression of prostate cancer, sun exposure and non-melonoma skin cancer are provided.
    Type: Grant
    Filed: August 27, 2014
    Date of Patent: August 29, 2017
    Assignee: MDNA Life Sciences Inc.
    Inventors: Ryan L. Parr, Robert Thayer, Gabriel Dakubo, Jennifer Creed, Kerry Robinson, Andrea Maggrah, Brian Reguly, Andrew Harbottle, Mark Birch-Machin