Abstract: The application provides methods of prognosing and classifying lung cancer patients into poor survival groups or good survival groups by way of a multigene signature, comprising at least 5 genes from Table 3. The application also includes kits and computer products for use in the methods of the application.

Abstract: A system for profiling lymphoma is provided that is based on the identification of sets of genes, which are characterized in that changes in expression of each gene within a set of genes can be correlated to one or more features of a specific lymphoma. The lymphoma profiling system provides for sets of “lymphoma profiling” genes and further provides for combinations of polynucleotide probes derived from one or more of the lymphoma profiling sets. These combinations of polynucleotide probes can be provided in solution or as an array. The combination of probes and the arrays can be used for disease prognosis, diagnosis, staging or grading, treatment management, monitoring of disease progression, predicting disease outcome or complications, and the like.