Patents Assigned to Med. College of Georgia Research Institute, Inc.
  • INDOLEAMINE 2,3-DIOXYGENASE, PD-1/PD-L PATHWAYS, AND CTLA4 PATHWAYS IN THE ACTIVATION OF REGULATORY T CELLS
    Publication number: 20100055111
    Abstract: The present invention includes methods of enhancing immune responses by administering an inhibitor of indoleamine-2,3-dioxygenase (IDO) along with one or more inhibitors of the PD-1/PD-L pathway and/or one or more inhibitors of the CTLA4 pathway.
    Type: Application
    Filed: February 14, 2008
    Publication date: March 4, 2010
    Applicants: Med. College of Georgia Research Institute, Inc., Regents of the University of Minnesota
    Inventors: Madhav D. Sharma, Bruce R. Blazar, Andrew L. Mellor, David H. Munn
  • Composition and Method for IN VIVO and IN VITRO Attenuation of Gene Expression Using Double Stranded RNA
    Publication number: 20090215880
    Abstract: Introduction of double stranded RNA into cells, cell culture, organs and tissues, and whole organisms, particularly vertebrates, specifically attenuates gene expression.
    Type: Application
    Filed: April 13, 2009
    Publication date: August 27, 2009
    Applicant: Med. College of Georgia Research Institute, Inc.
    Inventors: Yin-Xiong Li, Michael J. Farrell, Margaret J. Kirby
  • INDOLEAMINE 2,3-DIOXYGENASE PATHWAYS IN THE GENERATION OF REGULATORY T CELLS
    Publication number: 20090155311
    Abstract: The present invention provides methods for the control of the generation of regulatory T cells (Tregs) and uses thereof.
    Type: Application
    Filed: January 5, 2007
    Publication date: June 18, 2009
    Applicant: Med. College of Georgia Research Institute, Inc.
    Inventors: Wei Chen, Bruce R. Blazar, David Munn, Andrew Mellor
  • Composition and method for in vivo and in vitro attenuation of gene expression using double stranded RNA
    Publication number: 20090156520
    Abstract: Introduction of double stranded RNA into cells, cell culture, organs and tissues, and whole organisms, particularly vertebrates, specifically attenuates gene expression.
    Type: Application
    Filed: December 12, 2006
    Publication date: June 18, 2009
    Applicant: Med. College of Georgia Research Institute, Inc.
    Inventors: Yin-Xiong Li, Michael J. Farrell, Margaret L. Kirby