Abstract: Suturing devices, systems, and methods used to suture biological structures. The suturing devices can be configured to place sutures into body tissue from one side of the tissue without requiring a component on an opposite side of the tissue and without requiring insertion of components into the body tissue beyond the needles and the suture.

Abstract: Suturing devices and systems used to apply sutures and/or to close openings at, within, or into a biological structure. The suturing device can comprise an elongate member having a proximal end, a distal end, one or more distal arms, one or more proximal extensions, and one or more needles. A sheath may be used with the device to maintain or substantially maintain haemostasis while the device is used and while a procedure is performed in the biological structure.

Abstract: Suturing devices, systems, and methods used to suture biological structures. The suturing devices can be configured to place sutures into body tissue from one side of the tissue without requiring a component on an opposite side of the tissue and without requiring insertion of components into the body tissue beyond the needles and the suture.

Abstract: A suturing apparatus configured to suture an opening extending through an outer wall of the heart, such as a transapical opening, can comprise an elongate body having a proximal end, a distal end, a tapered or rounded tip, one or more arms, and one or more needles. A handle at the proximal end of the elongate body can be configured to be manipulated from outside of the heart. The elongate body can have a substantially constant outer diameter between the handle and the distal end. The arms can hold portions of suture a distance away from the outer diameter of the elongate body. The arms can be extendable from said body from a retracted position to an extended position. The arms in the extended position can point distally and form an acute angle with a longitudinal axis of the elongate body. The plurality of needles can be movable to pass through heart tissue into engagement with the suture portions held by the arms and back through the heart tissue to draw the suture portions through the heart tissue.