Abstract: The present disclosure provides a device having a circuit. The circuit includes at least one boost converter receiving power from an energy source, a square wave driver in series with the boost converter, an inductor in series with the square wave driver for converting a square wave to a sinusoidal wave, and a piezoelectric transducer in series with the inductor, the piezoelectric transducer connectable to a load. The device further includes a phase-locked loop coupled to the circuit to determine a resonance frequency of the piezoelectric transducer when the piezoelectric transducer is connected to the load.

Abstract: Vessel closure system that can be affixed in a spatially defined position for closing open blood vessels has a closure element, at least one pressure body arranged on the closure element and holding bands coupled to the closure element and made from a material having elastic properties. The pressure body is designed, when placed on an opened vessel of a patient, to apply increased pressure, in relation to other regions of the vessel, to a puncture site in the vessel. A skin adhesive layer is arranged on each holding band on the same side of the closure element as the pressure body. Each pressure body has a curvature projecting outwardly from the closure element such that lateral sides of the pressure body are closer to the closure element than a middle region of the pressure body between the lateral sides to provide the pressure body with an elongate pressure surface.

Abstract: A cochlear implant electrode arrangement is described that prevents post-surgical retraction of the electrode array from the cochlea. The arrangement includes an electrode lead that carries cochlear stimulation signals from an implanted signal processor, through an oval shaped posterior tympanotomy opening in the facial recess of a patient, to an electrode array implanted in a cochlea of the patient. A retraction limiter slides over the electrode lead through the posterior tympanotomy with projection arms aligned along the long diameter of the posterior tympanotomy, then is rotated to align the projection arms along the short diameter of the posterior tympanotomy, and secured to the electrode lead so that the projection arms prevent post-surgical retraction of the electrode lead back through the posterior tympanotomy.

Abstract: A portable rehab station, including left and right outriggers, each having a forward end and a rearward end, the left and right outriggers being pivotally connected at the bottom ends of the respective left and right frame members to pivot between retracted and expanded positions, the retracted position including the left and right outriggers being generally mutually parallel, and the expanded position including the left and right outriggers being spread out at an angle of between about six and ten degrees relative to each other; a front, ground-engageable caster connected to the forward end of each of the left and right outriggers and a rear, ground-engageable caster connected to the rearward end of each of the left and right outriggers; and an actuator assembly connected with the frame and operably connected with the left and right outriggers to selectively pivot the left and right outriggers between the retracted and expanded positions.

Abstract: A head fixation device in the form of a skull clamp comprises an opening device having an actuator positioned along an upright portion of the skull clamp near where a pin assembly contacts a patient's head for stabilization. The opening device can be actuated such that the relative distance between arms of the skull clamp can be opened, closed, or adjusted. The opening device is substantially positioned within one of the arms of the skull clamp. In some versions the skull clamp further comprises an attachment feature having an offset configuration.

Abstract: A composite implant device for use in a medical application, comprising a synthetically-derived mesh that mimics particular critical aspects of a biologically-derived mesh. The composite implant device can be used for the reinforcement and reconstruction of tissues within the body and can be comprised of a majority of synthetic components and minority of naturally-derived components which mimic the structure and function of a naturally-derived mesh.

Abstract: An injectable hyaluronic acid composition including a hyaluronic acid; a local anesthetic selected from the group consisting of amide and ester type local anesthetics or a combination thereof; and an ascorbic acid derivative in an amount which prevents or reduces the effect on the viscosity and/or elastic modulus G? of the composition caused by the local anesthetic upon sterilization by heat. Further, the medical and non-medical, such as cosmetic, use of such a composition, and to a method of manufacturing such a composition.

Abstract: A needle device including a housing. The housing includes a first housing element provided towards a proximal end of said needle device and a second housing element provided towards a distal end of said needle device. A cutting element having a sharp proximal end is arranged at a proximal end of said first housing element. A cannula having a blunt proximal end is fitted to the second housing element and an opening for the cannula is provided at the proximal end of the first housing element. The first housing element and the second housing element are moveable relative to each other between an extended position where the proximal end of the cannula does not extend beyond the proximal end of the cutting element and a compressed position where the cannula extends through the opening of the first housing element and past the proximal end of the cutting element.

Abstract: A system and method for the evaluation of hearing implant signal processing is described. A cochlear implant signal processor converts a speech signal input into multi-channel stimulation pulse sequences for a cochlear implant electrode array. A temporal feature processing module extracts temporal feature information from the stimulation pulse sequences. A speech recognition engine evaluates the temporal information using automatic speech recognition to produce speech recognition outputs corresponding to the speech signal input.

Abstract: A method for forming a desired bend angle in an orthodontic appliance comprising: obtaining desired bend angle; determining initial bend angle to be applied in gripped state; causing forming of a bend with initial bend angle; monitoring bending; in response to initial bend angle in the appliance in the gripped state being reached, causing the release of at least a portion of the appliance so that appliance is in the free state, measuring resultant angle of the bend in free state; selectively executing: in response to resultant angle being within a predefined tolerance of the desired bend angle, determining that desired bend angle has been reached; and in response to the resultant angle being outside the predefined tolerance level of the desired bend angle, iteratively applying an adjusted bend angle to the appliance in the gripped state until the desired bend angle is achieved as determined in the free state.

Abstract: A sheet structure formed from an extracellular matrix (ECM) composition that includes acellular ECM derived from small intestine submucosa (SIS) tissue, gentamicin and vancomycin. The sheet structure is configured to modulate inflammation of damaged biological tissue and induce cell and tissue proliferation, bioremodeling of the damaged biological tissue, and regeneration of new tissue and tissue structures with site-specific structural and functional properties, when the tissue structure is delivered to the damaged biological tissue.

Abstract: A method for collapsing a target vein in a patient. The method comprises providing an intravascular irritation element having a plurality of mechanical irritating objects, inserting the intravascular irritation element into a venous lumen of a target vein, and irritating the target vein by moving the plurality of mechanical irritating objects in contact with the inner surface thereof, thereby triggering a collapse of the target vein.

Abstract: Veterinary compositions and methods for production and use. A method of treating bees at or near a bee hive with a first and/or second veterinary composition is described including administering to bees a veterinary composition comprising at least cannabinoid, and/or at least two non-cannabinoid cannabis compounds, with or without a carrier, thereby enhancing bees performance.

Abstract: A compressed gas container and a flow control unit are retained within a rigid housing of a control device locally attached to an inflatable strap of a pneumatic tourniquet. The flow control unit, when triggered, is configured to selectively supply a dose of pressurized gas discharged from the gas container to an internal strap cavity, to achieve a predetermined cavity pressure for applying a required hemorrhage suppressing force onto a limb. In one embodiment, a strap restraining unit permits displacement of a free end of the strap without resistance until assuming a predetermined length sufficient to apply the hemorrhage suppressing force and which corresponds to a disposition of a restraining element at which it is in sufficiently close pressing relation with the strap to cause it to become restrained. The tourniquet is deployable in one embodiment by engaging an unattached end of a buckle frame with a large-area protruding part.

Abstract: The present invention relates to the method of lowering cholesterol in a patient in need thereof by administering to said patient a therapeutic effective amount of a compound selected from the group consisting of 1-alkyl, 2-acyl-glyceraldehyde-3-phosphate (G3P), 1-alkyl, 2-acyl glycerol and 1-alkyl, 2-acyl-glycerylphosphatidylethanolamine (GPE) or a pharmaceutically acceptable salt thereof.

Abstract: Honey-cannabinoid therapeutic compositions and methods.

Abstract: A method of detecting contractions in a user, the method may include providing alternating current with a determined frequency, through a first path in an abdominal tissue, between at least a first pair of electrodes positioned apart from each other over a first abdominal surface of the user. The method may further include repeatedly measuring a response of the abdominal tissue to excitation by the alternating current passing between at least a pair of electrodes, identifying at least one muscle contraction according to the changes in the response, and determining occurrence of uterine contractions based on at least one characteristic of the at least one muscle contraction. A system for detecting contractions in a user may include an alternating current generator, at least two electrodes, and a processor, operatively coupled to the at least two electrodes.

Abstract: Device adapted to perform appropriate forming of openings (3) made in the skull (2) during craniotomy with an opening (4) of enlarged diameter that may thereafter be filled with a standardized cranial plug, the device comprising a cylindrical body member (6) with a rear end extending into a shaft (8) coupled in a rotary power supply source and a frontal end provided with a cutting head (8a) with cutting teeth of triangular section and a guide head (10) comprising a first cylindrical portion (10a) having a diameter equivalent to the corresponding diameter of opening (3) that extends forwardly of the cutting head (8a) and is inserted into opening (3) stabilizing the device and allowing subsequent drilling of opening (3) with the cutting head (8a) to form the abovementioned opening (4) of enlarged diameter, the drilling operation being terminated with the contact of a circumferential ring (7) provided at the frontal end of the cylindrical body member (6) onto the skull (2).

Abstract: The invention relates to a method for preparing lead (212) for medical use. This method comprises the production of lead (212) by the decay of radium (224) in a generator comprising a solid medium to which the radium (224) is bound, followed by the extraction of the lead (212) from the generator in the form of an aqueous solution A1, characterised in that the lead (212) contained in the aqueous solution A1 is purified from the radiological and chemical impurities, also contained in said aqueous solution, by a liquid chromatography on a column. The invention also relates to an apparatus specially designed for automated implementation in a closed system of said method. It further relates to lead (212) produced by means of this method and this apparatus. Applications: manufacture of radiopharmaceuticals based on lead (212), useful in nuclear medicine for the treatment of cancers, particularly by a-radioimmunotherapy, or for medical imaging, in both humans and animals.