Patents Assigned to Mederis Diabetes, LLC
  • Publication number: 20250136656
    Abstract: Described herein are methods of syntheses and therapeutic uses of covalently modified peptides and/or proteins. The covalently modified peptides and/or proteins allow for improved pharmaceutical properties of peptide and protein-based therapeutics.
    Type: Application
    Filed: November 11, 2024
    Publication date: May 1, 2025
    Applicant: Mederis Diabetes LLC
    Inventor: John J. NESTOR
  • Publication number: 20240424062
    Abstract: Described herein are methods of syntheses and therapeutic uses of covalently modified peptides and/or proteins. The covalently modified peptides and/or proteins allow for improved pharmaceutical properties of peptide and protein-based therapeutics.
    Type: Application
    Filed: February 26, 2024
    Publication date: December 26, 2024
    Applicant: Mederis Diabetes LLC
    Inventor: John J. Nestor
  • Patent number: 11911447
    Abstract: Described herein are methods of syntheses and therapeutic uses of covalently modified peptides and/or proteins. The covalently modified peptides and/or proteins allow for improved pharmaceutical properties of peptide and protein-based therapeutics.
    Type: Grant
    Filed: June 16, 2021
    Date of Patent: February 27, 2024
    Assignee: Mederis Diabetes LLC
    Inventor: John J. Nestor
  • Publication number: 20230218564
    Abstract: The disclosure provides peptide products comprising a peptide covalently attached to a surfactant moiety which have improved properties, including increased duration of action and bioavailability. The peptide products are useful for treating insulin resistance, diabetes, obesity, metabolic syndrome and cardiovascular diseases, and conditions associated therewith, such as NASH and PCOS.
    Type: Application
    Filed: December 20, 2022
    Publication date: July 13, 2023
    Applicant: Mederis Diabetes LLC
    Inventor: John J Nestor
  • Publication number: 20220362345
    Abstract: Described herein are methods of syntheses and therapeutic uses of covalently modified peptides and/or proteins. The covalently modified peptides and/or proteins allow for improved pharmaceutical properties of peptide and protein-based therapeutics.
    Type: Application
    Filed: June 16, 2021
    Publication date: November 17, 2022
    Applicant: Mederis Diabetes LLC
    Inventor: John J. Nestor
  • Patent number: 11065304
    Abstract: Described herein are methods of syntheses and therapeutic uses of covalently modified peptides and/or proteins. The covalently modified peptides and/or proteins allow for improved pharmaceutical properties of peptide and protein-based therapeutics.
    Type: Grant
    Filed: November 20, 2013
    Date of Patent: July 20, 2021
    Assignee: Mederis Diabetes, LLC
    Inventor: John J. Nestor
  • Publication number: 20210077629
    Abstract: Described herein are methods of syntheses and therapeutic uses of covalently modified peptides and/or proteins. The covalently modified peptides and/or proteins allow for improved pharmaceutical properties of peptide and protein-based therapeutics.
    Type: Application
    Filed: September 23, 2019
    Publication date: March 18, 2021
    Applicant: Mederis Diabetes LLC
    Inventor: John J. NESTOR
  • Publication number: 20200352900
    Abstract: The disclosure provides peptide products comprising a peptide covalently attached to a surfactant moiety which have improved properties, including increased duration of action and bioavailability. The peptide products are useful for treating insulin resistance, diabetes, obesity, metabolic syndrome and cardiovascular diseases, and conditions associated therewith, such as NASH and PCOS.
    Type: Application
    Filed: January 3, 2019
    Publication date: November 12, 2020
    Applicant: Mederis Diabetes LLC
    Inventor: John J Nestor
  • Publication number: 20200289653
    Abstract: Described herein are methods of syntheses and therapeutic uses of covalently modified peptides and/or proteins. The covalently modified peptides and/or proteins allow for improved pharmaceutical properties of peptide and protein-based therapeutics.
    Type: Application
    Filed: March 21, 2020
    Publication date: September 17, 2020
    Applicant: Mederis Diabetes LLC
    Inventor: John J. Nestor
  • Publication number: 20200277351
    Abstract: Described herein are methods of syntheses and therapeutic uses of covalently modified peptides and/or proteins. The covalently modified peptides and/or proteins allow for improved pharmaceutical properties of peptide and protein-based therapeutics.
    Type: Application
    Filed: January 21, 2020
    Publication date: September 3, 2020
    Applicant: Mederis Diabetes LLC
    Inventor: John J. NESTOR
  • Patent number: 10577405
    Abstract: Described herein are methods of syntheses and therapeutic uses of covalently modified peptides and/or proteins. The covalently modified peptides and/or proteins allow for improved pharmaceutical properties of peptide and protein-based therapeutics.
    Type: Grant
    Filed: November 21, 2017
    Date of Patent: March 3, 2020
    Assignee: Mederis Diabetes LLC
    Inventor: John J. Nestor
  • Patent number: 10471127
    Abstract: Described herein are methods of syntheses and therapeutic uses of covalently modified peptides and/or proteins. The covalently modified peptides and/or proteins allow for improved pharmaceutical properties of peptide and protein-based therapeutics.
    Type: Grant
    Filed: May 17, 2012
    Date of Patent: November 12, 2019
    Assignee: Mederis Diabetes, LLC
    Inventor: John J. Nestor
  • Patent number: 10420844
    Abstract: Described herein are methods of syntheses and therapeutic uses of covalently modified peptides and/or proteins. The covalently modified peptides and/or proteins allow for improved pharmaceutical properties of peptide and protein-based therapeutics.
    Type: Grant
    Filed: March 6, 2018
    Date of Patent: September 24, 2019
    Assignee: Mederis Diabetes LLC
    Inventor: John J. Nestor
  • Publication number: 20140349928
    Abstract: Described herein are methods of syntheses and therapeutic uses of covalently modified peptides and/or proteins. The covalently modified peptides and/or proteins allow for improved pharmaceutical properties of peptide and protein-based therapeutics.
    Type: Application
    Filed: May 17, 2012
    Publication date: November 27, 2014
    Applicant: Mederis Diabetes, LLC
    Inventor: John J. Nestor