Patents Assigned to MEDESIS PHARMA
  • Treatment and prevention of injury due to radiation exposure
    Patent number: 11793831
    Abstract: The disclosure relates to the treatment and/or prevention of radiation damage by administering a reverse micelle system.
    Type: Grant
    Filed: July 5, 2019
    Date of Patent: October 24, 2023
    Assignee: MEDESIS PHARMA
    Inventors: Elsa Compte, Patrick Maurel, Sophie Grives-Jerphagnon, Cyril Lavaud, Lorraine Benigno-Anton, Jean-Claude Maurel
  • In situ preparation of cyano-bridged metal nanoparticles within a biocompatible reverse micellar system
    Patent number: 11278568
    Abstract: The present invention relates to a method for in situ preparation of cyano-bridged coordination polymers as metal nanoparticles within a biocompatible reverse micellar system by mixing at least two reverse micellar systems, each one containing at least one metal salt precursor. The invention also relates to the stabilization of theses nanoparticles by using a biocompatible reverse micellar system. This system takes part of the synthesis as a nanoreactor which comprises at least an acylglycerol, a sterol, lecithin, ethanol and water for the preparation of stable cyano-bridged metal nanoparticles without any use of additional stabilizer agent.
    Type: Grant
    Filed: July 8, 2016
    Date of Patent: March 22, 2022
    Assignees: MEDESIS PHARMA, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DE MONTPELLIER
    Inventors: Jean-Claude Maurel, Elsa Compte, Cyril Lavaud, Yannick Guari, Joulia Guari, Jérôme Long
  • Use of a reverse-micellar system for delivering chelators of radionuclides and metals
    Patent number: 10172954
    Abstract: The present invention relates to reverse-micellar systems comprising at least an active agent, an acylglycerol, a sterol, lecithin, ethanol and water, for use in chelation and/or sequestering of a radionuclide and/or a metal in a patient. The invention also relates to the reverse-micellar systems and to pharmaceutical compositions comprising said reverse-micellar systems.
    Type: Grant
    Filed: February 17, 2015
    Date of Patent: January 8, 2019
    Assignee: MEDESIS PHARMA
    Inventors: Caroline Bauer, Elsa Compte, Olivier Gremy, Laurent Miccoli, Jaime Francisco Angulo-Mora, Jean-Claude Maurel
  • Reverse micelle system comprising metal ions and use thereof
    Patent number: 9592218
    Abstract: The present invention relates to reverse micelle system based on sterols, acylglycerols, phospholipids or sphingolipids and metal ions. Reverse micelle system of the invention is able to cross mucosa and cellular membranes. It thus allows vectorization of metal ions to target sites. It is advantageously useful in the pharmaceutical and dietetic fields.
    Type: Grant
    Filed: March 24, 2011
    Date of Patent: March 14, 2017
    Assignee: MEDESIS PHARMA
    Inventor: Jean-Claude Maurel
  • Reverse micelle system comprising nucleic acids and use thereof
    Patent number: 9452136
    Abstract: The present invention relates to reverse micelle system based on sterols, acylglycerols, phospholipids or sphingolipids and nucleic acids. The reverse micelle system of the invention is able to cross mucosa and cellular membranes. It thus allows vectorization of nucleic acids to target sites. It is advantageously useful in the pharmaceutical and dietetic fields.
    Type: Grant
    Filed: October 22, 2014
    Date of Patent: September 27, 2016
    Assignee: MEDESIS PHARMA
    Inventor: Jean-Claude Maurel
  • Reverse micelle system comprising nucleic acids and use thereof
    Patent number: 8877237
    Abstract: The present invention relates to reverse micelle system based on sterols, acylglycerols, phospholipids or sphingolipids and nucleic acids. The reverse micelle system of the invention is able to cross mucosa and cellular membranes. It thus allows vectorization of nucleic acids to target sites. It is advantageously useful in the pharmaceutical and dietetic fields.
    Type: Grant
    Filed: March 24, 2011
    Date of Patent: November 4, 2014
    Assignee: Medesis Pharma
    Inventor: Jean-Claude Maurel
  • REVERSE MICELLE SYSTEM COMPRISING NUCLEIC ACIDS AND USE THEREOF
    Publication number: 20130065944
    Abstract: The present invention relates to reverse micelle system based on sterols, acylglycerols, phospholipids or sphingolipids and nucleic acids. The reverse micelle system of the invention is able to cross mucosa and cellular membranes. It thus allows vectorization of nucleic acids to target sites. It is advantageously useful in the pharmaceutical and dietetic fields.
    Type: Application
    Filed: March 24, 2011
    Publication date: March 14, 2013
    Applicant: MEDESIS PHARMA
    Inventor: Jean-Claude Maurel
  • REVERSE MICELLE SYSTEM COMPRISING METAL IONS AND USE THEREOF
    Publication number: 20130052279
    Abstract: The present invention relates to reverse micelle system based on sterols, acylglycerols, phospholipids or sphingolipids and metal ions. Reverse micelle system of the invention is able to cross mucosa and cellular membranes. It thus allows vectorization of metal ions to target sites. It is advantageously useful in the pharmaceutical and dietetic fields.
    Type: Application
    Filed: March 24, 2011
    Publication date: February 28, 2013
    Applicant: MEDESIS PHARMA
    Inventor: Jean-Claude Maurel