Patents Assigned to MEDESIS PHARMA
  • Patent number: 11793831
    Abstract: The disclosure relates to the treatment and/or prevention of radiation damage by administering a reverse micelle system.
    Type: Grant
    Filed: July 5, 2019
    Date of Patent: October 24, 2023
    Assignee: MEDESIS PHARMA
    Inventors: Elsa Compte, Patrick Maurel, Sophie Grives-Jerphagnon, Cyril Lavaud, Lorraine Benigno-Anton, Jean-Claude Maurel
  • Patent number: 11278568
    Abstract: The present invention relates to a method for in situ preparation of cyano-bridged coordination polymers as metal nanoparticles within a biocompatible reverse micellar system by mixing at least two reverse micellar systems, each one containing at least one metal salt precursor. The invention also relates to the stabilization of theses nanoparticles by using a biocompatible reverse micellar system. This system takes part of the synthesis as a nanoreactor which comprises at least an acylglycerol, a sterol, lecithin, ethanol and water for the preparation of stable cyano-bridged metal nanoparticles without any use of additional stabilizer agent.
    Type: Grant
    Filed: July 8, 2016
    Date of Patent: March 22, 2022
    Assignees: MEDESIS PHARMA, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DE MONTPELLIER
    Inventors: Jean-Claude Maurel, Elsa Compte, Cyril Lavaud, Yannick Guari, Joulia Guari, Jérôme Long
  • Patent number: 10172954
    Abstract: The present invention relates to reverse-micellar systems comprising at least an active agent, an acylglycerol, a sterol, lecithin, ethanol and water, for use in chelation and/or sequestering of a radionuclide and/or a metal in a patient. The invention also relates to the reverse-micellar systems and to pharmaceutical compositions comprising said reverse-micellar systems.
    Type: Grant
    Filed: February 17, 2015
    Date of Patent: January 8, 2019
    Assignee: MEDESIS PHARMA
    Inventors: Caroline Bauer, Elsa Compte, Olivier Gremy, Laurent Miccoli, Jaime Francisco Angulo-Mora, Jean-Claude Maurel
  • Patent number: 9592218
    Abstract: The present invention relates to reverse micelle system based on sterols, acylglycerols, phospholipids or sphingolipids and metal ions. Reverse micelle system of the invention is able to cross mucosa and cellular membranes. It thus allows vectorization of metal ions to target sites. It is advantageously useful in the pharmaceutical and dietetic fields.
    Type: Grant
    Filed: March 24, 2011
    Date of Patent: March 14, 2017
    Assignee: MEDESIS PHARMA
    Inventor: Jean-Claude Maurel
  • Patent number: 9452136
    Abstract: The present invention relates to reverse micelle system based on sterols, acylglycerols, phospholipids or sphingolipids and nucleic acids. The reverse micelle system of the invention is able to cross mucosa and cellular membranes. It thus allows vectorization of nucleic acids to target sites. It is advantageously useful in the pharmaceutical and dietetic fields.
    Type: Grant
    Filed: October 22, 2014
    Date of Patent: September 27, 2016
    Assignee: MEDESIS PHARMA
    Inventor: Jean-Claude Maurel
  • Patent number: 9173838
    Abstract: The present invention relates to a method for the preparation of reverse micelles based on sterols, acylglycerols and metal salt and to reverse micelles obtained thereby. They are advantageously useful in the pharmaceutical and dietetic fields.
    Type: Grant
    Filed: November 2, 2005
    Date of Patent: November 3, 2015
    Assignee: MEDESIS PHARMA SA
    Inventor: Jean-Claude Maurel
  • Patent number: 8877237
    Abstract: The present invention relates to reverse micelle system based on sterols, acylglycerols, phospholipids or sphingolipids and nucleic acids. The reverse micelle system of the invention is able to cross mucosa and cellular membranes. It thus allows vectorization of nucleic acids to target sites. It is advantageously useful in the pharmaceutical and dietetic fields.
    Type: Grant
    Filed: March 24, 2011
    Date of Patent: November 4, 2014
    Assignee: Medesis Pharma
    Inventor: Jean-Claude Maurel
  • Patent number: 8637314
    Abstract: The present invention relates generally to reverse-m ice liar system comprising a hydrosoluble therapeutically active agent. Reverse micelles according to the invention are particularly useful to deliver drugs. The present invention also relates to pharmaceutical composition comprising said reverse micelles and methods for preparing the same.
    Type: Grant
    Filed: November 2, 2005
    Date of Patent: January 28, 2014
    Assignee: Medesis Pharma SA
    Inventor: Jean-Claude Maurel
  • Publication number: 20130065944
    Abstract: The present invention relates to reverse micelle system based on sterols, acylglycerols, phospholipids or sphingolipids and nucleic acids. The reverse micelle system of the invention is able to cross mucosa and cellular membranes. It thus allows vectorization of nucleic acids to target sites. It is advantageously useful in the pharmaceutical and dietetic fields.
    Type: Application
    Filed: March 24, 2011
    Publication date: March 14, 2013
    Applicant: MEDESIS PHARMA
    Inventor: Jean-Claude Maurel
  • Publication number: 20130052279
    Abstract: The present invention relates to reverse micelle system based on sterols, acylglycerols, phospholipids or sphingolipids and metal ions. Reverse micelle system of the invention is able to cross mucosa and cellular membranes. It thus allows vectorization of metal ions to target sites. It is advantageously useful in the pharmaceutical and dietetic fields.
    Type: Application
    Filed: March 24, 2011
    Publication date: February 28, 2013
    Applicant: MEDESIS PHARMA
    Inventor: Jean-Claude Maurel
  • Publication number: 20090247492
    Abstract: The invention relates to compounds and their uses, particularly in the pharmaceutical and dietetic industries. The invention discloses complexes having Mn-SOD like activities, as well as methods for treating various diseases associated with oxidative stress, including cancer and inflammatory conditions, by administering said compounds. It further deals with pharmaceutical compositions or dietetic products comprising said compounds, more particularly useful to treat various diseases or disorders, in particular useful in the prevention or treatment of a disease involving an oxidative stress.
    Type: Application
    Filed: May 4, 2009
    Publication date: October 1, 2009
    Applicant: MEDESIS PHARMA S.A.,
    Inventors: Jean-Claude Maurel, Claude-Alain Cudennec
  • Publication number: 20070142306
    Abstract: The invention relates to organic complexes based on sitosterols, acylglycerols and strontium and to the use thereof in the pharmaceutical and dietetic fields. The invention also relates to methods for treating different diseases, particularly bone or blood diseases, by the administration of the aforementioned complexes. The invention further relates to pharmaceutical compositions containing said complexes, in particular for the treatment of bone diseases, such as osteoporosis, and for the treatment of blood diseases.
    Type: Application
    Filed: November 15, 2004
    Publication date: June 21, 2007
    Applicant: MEDESIS PHARMA SA
    Inventors: Jean-Claude Maurel, Claude-Alain Cudennec, Patrick Poucheret