Abstract: A composition based on natural substances, intended for oral administration, useful in the maintenance of the correct skin hydration and in the prevention and/or the treatment of the effects of skin ageing, in particular wrinkles, is described. The composition comprises in combination: ceramides from rice, fish cartilage hydrolysate, and one or more amino acids selected from L-proline, L-lysine, L-valine and L-cysteine.