Abstract: The present invention provides methods of treating an angiogenesis-related disease of a subject using a therapeutically effective amount of a modified endostatin protein. In particular, the methods encompass treating an angiogenesis-related disease of a subject using a combination of the modified endostatin, and a known cancer therapy agent such as a chemotherapy agent, or a radiotherapy agent.
Type:
Grant
Filed:
April 29, 2005
Date of Patent:
December 30, 2008
Assignee:
Medgenn (Hong Kong) Ltd
Inventors:
Yongzhang Luo, Zhuobing Zhang, Qingxin Lei, Yan Sun, Jinwan Wang