Abstract: There is provided a method for creating a personalized reference interval (PRI), comprising: receiving a digital profile of a patient including demographic parameters and associated values, and medical history data parameters and associated values; receiving a clinical test result including a measured value of at least one analyte; accessing a dataset storing digital profiles of other patients; identifying a subset of the dataset based a correlation according to a similarity requirement between demographic parameter(s) of the patient and of other patients, and between the medical history of the patient and the other patients; calculating a PRI for each respective analyte of the clinical test result of the patient according to an analysis of corresponding values of the analyte of the subset, wherein the PRI is dynamically calculated using the most updated version of the dataset.

Abstract: An interactive system and method allow for broadcast of basic content data along with data that define graphical inserts that can be played with or super-imposed on screens of the decoded broadcast. Coordinated pages or screens may be transmitted to audience secondary devices, such as smart phones, tablet computers, and so forth. Audience members may participate in an interactive experience by selecting options provided on the secondary devices. Audience responses are received, aggregated, and rules applied in accordance with the desired experience. The graphical indicia are altered during the broadcast, and optionally during or just following a period for audience feedback.

Abstract: A radiation-treatment planning apparatus accesses imaging information regarding at least a patient's treatment volume and surface information regarding dynamic surfaces within the radiation-treatment environment as pertains to the radiation treatment. The apparatus acquires the imaging information using a first imaging technology and the surface information using a second technology that is different than the first imaging technology. The apparatus uses the imaging and surface information to influence a radiation treatment plan for treating the treatment volume with radiation to accommodate dynamic physical changes within the radiation-treatment environment during the radiation treatment of the treatment volume.

Abstract: A method of evaluating gastrointestinal cancer risk. The method comprises generating a set of features comprising a plurality of current blood test results from a blood collected from a target individual, providing at least one classifier generated according to an analysis of a plurality of respective historical blood test results of each of another of a plurality of sampled individuals, and evaluating, using a processor, a gastrointestinal cancer risk of the target individual by classifying the set of features using the at least one classifier.

Abstract: The present invention demonstrates for the first time that FAT1 plays an important role in modulating PDCD4 expression, which in turn regulates AP-1 dependent transcription, controls processes crucial for migration and invasion in cancer cells, controls induction of a pro-inflammatory micro environment in cancer cells. The study illustrates a link between inflammation and cancer in cells or in a subject. This work highlights the importance of FAT1 in the induction of the cellular pathways of migration and invasion, proteolysis of the ECM and the expression of pro-inflammatory molecules leading to a favorable micro environment for tumor and cancer progression.

Abstract: A method of evaluating gastrointestinal cancer risk. The method comprises generating a set of features comprising a plurality of current blood test results from a blood collected from a target individual, providing at least one classifier generated according to an analysis of a plurality of respective historical blood test results of each of another of a plurality of sampled individuals, and evaluating, using a processor, a gastrointestinal cancer risk of the target individual by classifying the set of features using the at least one classifier.

Abstract: An ultrasound diagnosis apparatus according to an embodiment includes a decomposing unit, a diffusion filter unit, an adjusting unit, and a reconstructing unit. The decomposing unit decomposes ultrasound image data into low-frequency and high-frequency decomposed image data at each of a predetermined number of levels, by a multi-resolution analysis. The diffusion filter unit applies a diffusion filter to the low-frequency and high-frequency decomposed image data at the lowest level and applies, at each of the levels other than the lowest, a diffusion filter to data output from the level immediately underneath and to the high-frequency decomposed image data, and also generates edge information for each of the levels. The adjusting unit adjusts a signal level of the high-frequency decomposed image data for each of the levels, based on the edge information. The reconstructing unit obtains corrected data of the ultrasound image data by performing a multi-resolution synthesis.

Abstract: A biopsy device includes a coring cannula, a retract stylet, and a localization needle. The coring cannula has a longitudinal axis and a shaft centered on the axis. The stylet has a tip containing at least one blade and a central passage. The localization needle has a channel and is slidably disposed within the central passage. A drive mechanism rotates the cannula and moves the cannula in a direction parallel to the longitudinal axis of the cannula. A guide element has a first end and a second end and is slidably disposed within the channel of the localization needle. The guide element is movable from a first position to a second position within the localization needle.

Abstract: A method and a device for recognition of paravasal bleeding upon a supplying of blood to a vascular access via a line and/or upon the removal of blood from a vascular access via a line is provided. A device for extracorporeal blood treatment comprising a device for recognition of paravasal bleeding is also provided. The method and the device are based on the change of arterial pressure in the arterial branch or the venous pressure in the venous branch of the extra-corporeal circuit being registered during the extracorporeal blood treatment. One aspect of the method and the device is that pressure changes that come from a pressure level exhibiting a large difference from a reference value are more strongly considered than those that come from a pressure level that exhibits only a minor difference from the reference value.

Abstract: A disposable infusion device comprises a reservoir that holds a liquid medicament, a pump that displaces the liquid medicament from the reservoir to the patient, at least one valve that conducts the displaced medicament from the reservoir, and a fluid conduit that conducts the medicament from the reservoir, to the pump, and to the patient. The device includes a layered structure that defines the reservoir, pump, valve, and fluid conduit.

Abstract: A sensor card for determining analytes in liquid and gas samples with films connected to one another in sheetlike fashion, namely a sensor film facing the sample with openings and a covering film remote from the sample with openings for electrical tapping, at least one sensor being provided and arranged between the sensor film and the covering film. There is provided between the sensor film and the covering film at least one intermediate film, in which cutouts are provided, the sensor being arranged in one of the cutouts. The sensor card provides a homogeneous thickness, which brings about a reliable sealing of the flow channels for the liquid sample if the sensor card is connected to a plate that partially forms the flow channels within the analysis system. Furthermore, the invention relates to a method for producing such a sensor card.

Abstract: The present invention provides an X-ray CT apparatus capable of obtaining each tomographic image indicative of X-ray tube voltage dependent information of a subject with the optimum image quality by less reduced exposure. The X-ray CT apparatus includes device for setting a plurality of X-ray tube voltages and sets imaging conditions used in the photography using the respective X-ray tube voltages in such a manner that respective image noise of tomographic images photographed at the X-ray tube voltages become substantially identical to one another. The setting of the imaging conditions is the setting of X-ray tube currents. The X-ray tube currents are set based on geometrical characteristic amounts of the subject determined from each scout image in such a manner that the respective image noise of the tomographic images photographed at the plurality of X-ray tube voltages become substantially identical to one another.

Abstract: A process for secure distribution of digital audiovisual streams according to a standard, normalized or proprietary format including separating an original stream into two parts, transmitting the parts to addressee equipment, generating a modified main stream having a format of the original stream and complementary information with any format including digital information suitable to permit reconstruction of the original stream, and transmitting the modified stream from a distribution server via separate paths during distribution in an extended, secure multicasting mode to the addressee equipment from a secure central server passing via at least one router and at least one switch connecting the addressee equipment to the central server via at least one access point.

Abstract: A cardiac stimulator has an implantable cardiac lead that carries a temperature sensitive element with a surface thereof in contact with biological matter. The temperature sensitive element emits a temperature signal corresponding to the temperature of biological matter, such as blood, in contact with the surface of the temperature sensitive element. Processing circuitry receives the temperature signal and determines a variability thereof within a selected time interval. A status signal is emitted dependent on this variability.

Abstract: A process for distributing digital video sequences in accordance with a nominal stream format including a succession of frames, each frame including at least one digital block regrouping a plurality of coefficients corresponding to simple, digitally coded visual elements is disclosed.

Abstract: A method for delivering a nominal audiovisual stream including nominal coefficients to a receiving site including a secure gateway includes modifying, in the nominal audiovisual stream, at least one nominal coefficient among the nominal coefficients to generate a main digital stream; generating complementary information so that the nominal audiovisual stream is implemented from the complementary information and main digital stream at the receiving site; performing cryptographic operations on the secure gateway with the complementary information; and causing the gateway to transmit the complementary information to an audiovisual processing peripheral to enable the nominal audiovisual stream to be implemented at the audiovisual processing peripheral.

Abstract: A method for distributing video sequences according to a nominal flow format that describes a multiplicity of audiovisual scenes, each scene including a multiplicity of hierarchized audiovisual objects and a descriptor of the hierarchy and of spatial and temporal relationships among the objects, each video object including at least one complete I-VOP digital plane, including generating a first modified flow having the format of a nominal flow and a second flow of any format including digital information required for reconstruction of modified planes by analyzing the flow of video sequences, separately transmitting the two flows generated from a server to destination equipment, and calculating on the destination equipment a synthesis of a flow of the nominal format as a function of the first and second flows.

Abstract: A process for secure distribution of digital audiovisual streams according to a standard, normalized or proprietary format including separating an original stream into two parts, transmitting the parts to addressee equipment, generating a modified main stream having a format of the original stream and complementary information with any format including digital information suitable to permit reconstruction of the original stream, and transmitting the modified stream from a distribution server via separate paths during distribution in an extended, secure multicasting mode to the addressee equipment from a secure central server passing via at least one router and at least one switch connecting the addressee equipment to the central server via at least one access point.

Abstract: A method for distributing video sequences according to a nominal flow format including a succession of frames, each including at least one I block corresponding to a complete digital I image, each I image being broken down into blocks and macroblocks dependent on each other by correlation coefficients, including: analyzing a flow of sequences; generating a first modified flow having a format of a nominal flow and having I images modified by substitution of selected correlation coefficients by coefficients of the same type, but being random, and a second flow of any format including the substituted correlation coefficients and digital information which can enable reconstruction of the modified images; transmitting the first and second modified flows from a server to destination equipment; and calculating on the destination equipment a synthesis of a flow of the nominal format as a function of the first and second flows.

Abstract: A process for the secure distribution of compressed digital texts formed by blocks of binary data stemming from digital transformations applied to an original text, and including two stages: a preparatory stage including modifying at least one binary data in one of the blocks according to at least one substitution operation including extraction of the binary data in a block and its replacement by a decoy, and a transmission stage of a modified compressed digital text in conformity with the format of the original text, constituted of blocks modified during the course of the preparatory stage, and by a separate path of the modified compressed digital text, of digital complementary information permitting reconstitution of the original compressed digital text on the equipment of the addressee from the modified compressed digital text and from the complementary information.