Patents Assigned to Medical Biological Sciences, Inc.
  • Patent number: 4547390
    Abstract: This invention relates to implantable porous prostheses for use as bone or hard tissue replacements anywhere in the body. The porous implants comprise loose, individual polymeric particles of a specified size, coated with a hydrophilic material and barium sulfate particles. The prostheses are biologically compatible in the body and promote bone and tissue ingrowth and attachment. This invention also relates to a method for producing the novel prosthetic devices disclosed herein.
    Type: Grant
    Filed: September 30, 1982
    Date of Patent: October 15, 1985
    Assignee: Medical Biological Sciences, Inc.
    Inventors: Arthur Ashman, Paul F. Bruins
  • Patent number: 4547327
    Abstract: A porous implantable oral prosthesis which can be used to replicate and replace any hard tissue portion of the mouth such as bone and teeth is described. The prosthesis comprises sintered polymeric particles coated with a hydrophilic material. The polymeric particles vary in size so as to provide an area of relatively coarse porosity where the prosthesis is intended to interface with bone tissue and relatively fine porosity where it is intended to interface with soft tissue. A process for producing such prosthesis by filling a mold with appropriate molding compounds comprised of polymeric particles and a hydrophilic monomer, sintering the particles and polymerizing the monomer by dielectric heating, removing the sintered material from the cooled mold, and placing the prosthesis in a hot liquid to remove residues is described. An entire tooth, including a nonporous crown may be produced.
    Type: Grant
    Filed: August 8, 1984
    Date of Patent: October 15, 1985
    Assignee: Medical Biological Sciences, Inc.
    Inventors: Paul F. Bruins, Arthur Ashman
  • Patent number: 4536158
    Abstract: A porous implantable oral prosthesis which can be used to replicate and replace any hard tissue portion of the mouth such as bone and teeth is described. The prosthesis comprises sintered polymeric particles coated with a hydrophilic material. The polymeric particles vary in size so as to provide an area of relatively coarse porosity where the prosthesis is intended to interface with bone tissue and relatively fine porosity where it is intended to interface with soft tissue. A process for producing such prosthesis by filling a mold with appropriate molding compounds comprised of polymeric particles and a hydrophilic monomer, sintering the particles and polymerizing the monomer by dielectric heating, removing the sintered material from the cooled mold, and placing the prosthesis in a hot liquid to remove residues is described. An entire tooth, including a nonporous crown may be produced.
    Type: Grant
    Filed: September 30, 1982
    Date of Patent: August 20, 1985
    Assignee: Medical Biological Sciences, Inc.
    Inventors: Paul F. Bruins, Arthur Ashman
  • Patent number: 4535485
    Abstract: This invention relates to implantable porous prostheses for use as bone or hard tissue replacements anywhere in the body. The porous implants comprise loose, individual polymeric particles of a specified size, coated with a hydrophilic material and barium sulfate particles. The prostheses are biologically compatible in the body and promote bone and tissue ingrowth and attachment. This invention also relates to a method for producing the novel prosthetic devices disclosed herein.
    Type: Grant
    Filed: March 12, 1982
    Date of Patent: August 20, 1985
    Assignee: Medical Biological Sciences, Inc.
    Inventors: Arthur Ashman, Paul F. Bruins