Patents Assigned to Medical Collage of Wisconsin, Inc.
  • Bifunctional and trifunctional nitrone spin trapping compounds and uses thereof
    Patent number: 8143420
    Abstract: Methods and compositions for detecting free radicals, the compositions being spin trapping compounds comprising a nitrone having a detecting moiety and optionally having a targeting moiety for targeting the nitrone to an organ, a cell, an organelle or a molecule of interest for directly detecting free radicals, especially free radicals in biological samples.
    Type: Grant
    Filed: December 24, 2008
    Date of Patent: March 27, 2012
    Assignees: Medical Collage of Wisconsin, Inc., Université de Provence
    Inventors: Micael Joel Hardy, Marcos Lopez, Balaraman Kalyanaraman, Neil Hogg, Olivier Ouari, Paul Tordo