Patents Assigned to Medical Defense Technology, LLC
  • Patent number: 6749831
    Abstract: Compare core LPS (lacking O-polysaccharide side chains) from Gram-negative bacteria are incorporated into a vaccine typically in liposomes. The complete core of E. coli K 12 is particularly useful. Upon administration to a mammal the vaccine stimulates synthesis of antibodies which are cross-protective against smooth and rough forms of LPS from at least two different Gram-negative bacterial strains having different core structures.
    Type: Grant
    Filed: April 25, 2000
    Date of Patent: June 15, 2004
    Assignee: Medical Defense Technology, LLC
    Inventors: Elliott Bennett-Guerrero, George Robin Barclay, Ian Raymond Poxton, Thomas James McIntosh, David Scott Snyder