Abstract: A device and method are provided for needle penetrating and filling a chamber with a predetermined substance, and laser resealing a resulting needle hole in the device. A needle penetrable and laser resealable portion of the device is pierceable with a needle to form a needle aperture therethrough to fill the chamber through the needle, and is laser resealable to hermetically seal the needle aperture by applying laser radiation at a predetermined wavelength and power thereto. The needle penetrable and laser resealable portion defines a predetermined wall thickness in an axial direction thereof, and includes a thermoplastic that substantially prevents the formation of particles released into the chamber from the needle penetrable and laser resealable portion during penetration by and withdrawal of the needle.
Abstract: Apparatus for molding and filling a container having a container body defining an opening in communication with an interior chamber for receiving a substance therein, and a container closure including stopper receivable within the opening for sealing the opening and substance received in the container. A mold includes within the aseptic chamber plural mold cavities shaped to form the container closure and container body, and substantially sterile surfaces extending about and contiguous to the peripheries of the mold cavities. An assembly device including end-of-arm tooling having an engaging portion engageable with each of the container body and container closure is movable relative to the mold to engage and de-mold the substantially sterile container closure and container bodies from the mold cavities. Flexible barriers are coupled to the mold and the tool to substantially prevent the passage of contaminants from the molding machine and tool therethrough.
Type:
Grant
Filed:
March 13, 2006
Date of Patent:
February 17, 2009
Assignee:
Medical Instill Technologies, Inc.
Inventors:
Daniel Py, Benoit Adamo, John Guthy, Nathaniel Houle, Jeffrey Willey
Abstract: A device defining a chamber for receiving a substance and a thermoplastic portion in fluid communication with the chamber is provided along with a method of filling and sealing the substance within the chamber. The thermoplastic portion defines a penetrable region that is penetrable by a filling member and is heat resealable to hermetically seal an aperture therein by applying laser radiation at a predetermined wavelength and power. The thermoplastic portion comprises a thermoplastic body defining a predetermined wall thickness and includes a styrene block copolymer, an olefin and a predetermined amount of pigment allowing the body to absorb laser radiation at the predetermined wavelength, substantially prevent the passage of radiation through the predetermined wall thickness, and hermetically seal the aperture in the penetrable region in a predetermined time period.
Abstract: Device and method for needle penetrating and filling a chamber with a predetermined substance, and laser resealing a resulting needle hole in the device. A needle penetrable and laser resealable portion is pierceable with a needle to form a needle aperture therethrough to fill the chamber, and is laser resealable to hermetically seal the needle aperture by applying laser radiation. The needle penetrable and laser resealable portion defines a predetermined wall thickness in an axial direction thereof, and includes a thermoplastic that substantially prevents the formation of particles released into the chamber during penetration by and withdrawal of the needle.
Abstract: A contact lens container includes a body defining a cavity that is sized to hold a contact lens. A stopper is in fluid communication with the cavity and the stopper includes a resealable portion that is received into a channel. The resealable portion has a predetermined wall thickness in an axial direction thereof, the resealable portion defines a needle penetration region that is pierceable with a needle to form a needle aperture therethrough, and is heat resealable to hermetically seal the needle aperture.
Type:
Grant
Filed:
March 24, 2006
Date of Patent:
August 12, 2008
Assignee:
Medical Instill Technologies, Inc.
Inventors:
Daniel Py, Benoit Adamo, John Guthy, Giovanni Rodriguez