Patents Assigned to Medical Research and Infrastructure Fund of Tel-Aviv Sourasky Medical Center
  • Isoflavone derivatives and uses thereof
    Patent number: 8338624
    Abstract: Isoflavone derivatives are provided comprising a carboxyalkylene moiety linked via its alkylene chain to the aromatic ring and via its carboxy group to an aminoalkyleneamino residue, which, in turn, is covalently linked to a functional group B. The isoflavone derivatives are preferably derived from biochanin A, genistein, and daidzein, and the functional group B is preferably an amino protecting group. These isoflavone derivatives are useful for treating or preventing diseases or disorders associated with estrogen receptor functioning.
    Type: Grant
    Filed: February 20, 2008
    Date of Patent: December 25, 2012
    Assignees: Yeda Research and Development Co., Ltd., Medical Research and Infrastructure Fund of Tel-Aviv Sourasky Medical Center
    Inventors: Fortune Kohen, Dalia Somjen, Naftali Stern, Veronica Frydman, Tikva Kulik, Batya Gayer