Abstract: A thermal regulation blanket includes a plurality of cells with a first reagent. A plurality of pouches with a second reagent are disposed within the plurality of cells. A plurality of dividers are disposed between each of the plurality of cells. A thermally conductive layer is disposed over the cells and the plurality of dividers. When the first reagent and the second reagent mix, a thermal reaction occurs which modifies a temperature of the thermally conductive layer. A method of providing thermal therapy to a patient includes positioning the patient on a thermal regulation blanket, an abdomen of the patient is engaged with at least one abdominal blanket of the thermal regulation blanket. At least one cell of the thermal regulation blanket is activated to begin providing thermal therapy to the patient. A temperature of the thermal regulation blanket is monitored with a temperature sensor. At least one additional cell is activated to adjust the temperature of the thermal regulation blanket.

Abstract: A cooling device includes a tube having an interior formed by a first and second film welded together. The tube has a peelable heat seal connecting a portion of the first film with a portion of the second film. The peelable heat seal divides the interior into a first chamber and a second chamber separated from the first chamber. The interior of the first chamber includes one or more materials which have an endothermic heat of solution in water. The interior of the second chamber contains water. The peelable heat seal has an adhesive force that is overcome by an application of an external force to one of the chambers allowing the material in the first chamber and the water in the second chamber to mix.