Patents Assigned to Medicarb AB
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Patent number: 7153492Abstract: An effervescent solid composition of matter is provided, which comprises, as an active component, a substance selected from chitosan, its derivatives and salts thereof and a second component capable of releasing CO2 in an acidic environment. Also, methods for treatment of a mammal suffering from a dermal wound, or for prophylactic or wound-healing treatment of lactating animals prone to develop or suffering from mastitis, are provided. The methods comprise the steps of: a) admixing said effervescent solid composition of matter with an aqueous liquid to form a solution or suspension thereof; b) contacting said animals with said solution or suspension to provide such treatment.Type: GrantFiled: April 12, 2002Date of Patent: December 26, 2006Assignee: Medicarb ABInventors: Torbjörn Mathisen, Marcus Back, Åsa Hellman
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Patent number: 6896902Abstract: An effervescent solid composition of matter is provided, which comprises, as an active component, a substance selected from chitosan, its derivatives and salts thereof and a second component capable of releasing CO2 in an acidic environment. Also, methods for treatment of a mammal suffering from a dermal wound, or for prophylactic or wound-healing treatment of lactating animals prone to develop or suffering from mastitis, are provided. The methods comprise the steps of: a) admixing said effervescent solid composition of matter with an aqueous liquid to form a solution or suspension thereof; b) contacting said animals with said solution or suspension to provide such treatment.Type: GrantFiled: April 12, 2002Date of Patent: May 24, 2005Assignee: MEDICARB ABInventors: Torbjörn Mathisen, Marcus Back, Åsa Hellman
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Patent number: 6653457Abstract: A method of preparing conjugates by means of covalent coupling of a polysaccharide selected from heparin, heparin derivatives, at least partially deacerylated dermatan sulphate and dextran sulphate and a solid substance containing primary amino groups, said method comprising the following steps: a) reduction of the saccharide so that its terminal monosaccharide unit is converted to an alditol; b) periodate oxidation of the alditol formed in step a) to the formation of a terminal aldehyde group under cleavage of the monosaccharide unit between two vicinal groups selected from hydroxyl and amino groups; and c) reductive coupling of the alditol via the aldehyde group to the amino group of the solid substrate.Type: GrantFiled: June 27, 2002Date of Patent: November 25, 2003Assignee: Medicarb ABInventors: Olle Larm, Ibrahim Gouda
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Patent number: 6630458Abstract: Use of a composition comprising chitosan in combination with a polysaccharide selected from heparin, heparan sulphate and dextran sulphate, as an active component in a solvent, for the manufacture of a teat dipping solution for lactating animals, particularly cows. The invention also relates to a process for prophylactic or wound healing treatment of lactating animals, particularly cows, against mastitis.Type: GrantFiled: January 19, 1999Date of Patent: October 7, 2003Assignee: Medicarb ABInventors: Olle Larm, Marcus Back
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Patent number: 6486140Abstract: The use of chitosan and a polysaccharide immobilized thereto selected from heparin, heparan sulphate and dextran sulphate for the manufacture of an agent capable of preventing or substantially reducing undesirable adhesion of damaged tissue with adjacent or surrounding tissues in connection with wound healing; and a process for the use of such agent.Type: GrantFiled: October 5, 1999Date of Patent: November 26, 2002Assignee: Medicarb ABInventors: Hans-Arne Hansson, Gunilla Johansson-Rudén, Olle Larm
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Patent number: 6207653Abstract: The use of heparin or heparan sulphate in combination with chitosan for the manufacture of a medicament for the prevention or treatment of infections caused by herpes virus in mammal including man; and a process for the treatment of infectious diseases caused by herpes viruses.Type: GrantFiled: January 19, 1999Date of Patent: March 27, 2001Assignee: Medicarb ABInventors: Olle Larm, Marcus Back, Tomas Bergström
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Patent number: 5902798Abstract: The invention relates to a method for promoting the healing of dermal wounds by applying a composition containing chitosan and the polysaccharide, heparin or heparan sulfate. Heparin or heparan sulfate can be immobilized to chitosan by ionic or covalent bonds, and the degree of N-acetylation of chitosan can range from 25% to 90%. The composition can include a cellulose derivative as an additional polysaccharide to increase the viscosity of the composition. The combination of chitosan and polysaccharide, when applied to a wound site, effectively stimulates and accelerates wound healing.Type: GrantFiled: December 31, 1996Date of Patent: May 11, 1999Assignee: Medicarb ABInventors: Ibrahim Gouda, Olle Larm
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Patent number: 5885647Abstract: A process for coating of an intraocular lens to impart tissue compatibility thereto, comprising the steps: a) priming said lens using a solution of a polyamine; b) coating the lens treated in step a) above with a solution of a periodate-oxidized polysaccharide selected from heparin, heparain sulphate, and chondroitin sulphate to stabilize said polyamine by covalent and/or ionical cross-linking; c) coating the lens treated in step b) above with a solution of a polyamine; and d) coating the lens treated according to step c) above with a solution of a periodate-oxidized polysaccharide selected from heparin, heparain sulphate, and chondroitin sulphate in the presence of a cyanoborohydride to convert formed labile Schiff's bases to stable secondary amines.Type: GrantFiled: May 20, 1997Date of Patent: March 23, 1999Assignee: Medicarb ABInventors: Olle Larm, Ibrahim Gouda
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Patent number: 5711938Abstract: Oral hygiene composition containing in combination chitosan and a sulphated, negatively charged polysaccharide in a biologically active amount; a process of improving oral hygiene in a mammal including man; and use of chitosan in combination with a sulphated, negatively charged polysaccharide for the manufacture of dentally active oral hygiene compositions.Type: GrantFiled: October 31, 1996Date of Patent: January 27, 1998Assignee: Medicarb ABInventor: Olle Larm
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Patent number: 5668193Abstract: A solid substrate, the surface of which has been modified to introduce reactive groups of a hydrophilic nature thereon, the modification being provided by a primer comprising a first polysaccharide containing as reactive groups amino and hydroxyl groups; and a process for the preparation of such solid substrate.Type: GrantFiled: December 5, 1995Date of Patent: September 16, 1997Assignee: Medicarb ABInventors: Ibrahim Gouda, Olle Larm
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Patent number: 4707471Abstract: Water-soluble aminated .beta.-1,3-bound D-glucan and macrophage-stimulating composition containing as an active constituent such glucan.Type: GrantFiled: December 11, 1984Date of Patent: November 17, 1987Assignee: Medicarb ABInventors: Olle Larm, Rolf Seljelid