Abstract: A liquid pharmaceutical composition is contemplated that comprises a pharmaceutically effective amount of a drug dissolved or dispersed in an aqueous medium. The aqueous medium consists essentially of water, about 3% to about 10% w/v polyvinylpyrrolidone, about 60% to about 75% w/v of C3-C6 polyol that includes more than 55% w/v of a non-reducing disaccharide, trisaccharide or tetrasaccharide such as sucrose, optionally about 0.01% to about 0.5% w/v of a glycyrrhetic acid, glycyrrhizinate derivative or salt thereof, and one or more flavorants, and preferably includes one or more preservatives. The liquid composition is room temperature stable, and may have a pleasant taste.
Type:
Application
Filed:
February 25, 2005
Publication date:
January 19, 2006
Applicant:
MEDICIS PEDIATRICS, INC.
Inventors:
Emmett Clemente, Bhiku Patel, Kuljit Bhatia, Frank Sorgi, Emil Kakkis