Abstract: The present invention is related to a composition for promoting hair growth or inhibiting hair loss comprising a growth factor selected from the group consisting of VEGF, FGF?, FGF?, TGF-?, IGF, KGF, and SCF, as an active ingredient, according to the present invention, there is an effect of promoting hair growth and preventing hair loss by regulating the hair cycle of patients with hair loss, without causing side effects such as skin irritation and the like.

Abstract: The present invention relates to a method for improving the production of a difficult-to-express recombinant protein in a recombinant microorganism, and more particularly to a method for improving the production of a difficult-to-express recombinant protein by use of a recombinant microorganism into which a gene encoding a target protein and an sRNA against a gene encoding ribonuclease P are introduced. According to the present invention, expressions of a large recombinant protein, a difficult-to-express protein and a useful protein can be dramatically increased by reducing expression of the rnpA gene.